Zobrazeno 1 - 10
of 271
pro vyhledávání: '"A. S. Krolewski"'
Autor:
Christopher A. Simeone, Joseph L. Wilkerson, Annelise M. Poss, James A. Banks, Joseph V. Varre, Jose Lazaro Guevara, Edgar Javier Hernandez, Bushra Gorsi, Donald L. Atkinson, Tursun Turapov, Scott G. Frodsham, Julio C. Fierro Morales, Kristina O’Neil, Barry Moore, Mark Yandell, Scott A. Summers, Andrzej S. Krolewski, William L. Holland, Marcus G. Pezzolesi
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-8 (2022)
Abstract Adiponectin, encoded by ADIPOQ, is an insulin-sensitizing, anti-inflammatory, and renoprotective adipokine that activates receptors with intrinsic ceramidase activity. We identified a family harboring a 10-nucleotide deletion mutation in ADI
Externí odkaz:
https://doaj.org/article/250d25ef59fc4c589b2a1e3ae70ec7b4
Autor:
Zaipul I. Md Dom, Caterina Pipino, Bozena Krolewski, Kristina O’Neil, Eiichiro Satake, Andrzej S. Krolewski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract We recently identified a kidney risk inflammatory signature (KRIS), comprising 6 TNF receptors (including TNFR1 and TNFR2) and 11 inflammatory proteins. Elevated levels of these proteins in circulation were strongly associated with risk of t
Externí odkaz:
https://doaj.org/article/68f29930016d4f749fe3b988b98a2ea3
Autor:
Hiroki Kobayashi, Helen C. Looker, Eiichiro Satake, Francesca D’Addio, Jonathan M. Wilson, Pierre Jean Saulnier, Zaipul I. Md Dom, Kristina O’Neil, Katsuhito Ihara, Bozena Krolewski, Hannah S. Badger, Adriana Petrazzuolo, Domenico Corradi, Andrzej Galecki, Parker C. Wilson, Behzad Najafian, Michael Mauer, Monika A. Niewczas, Alessandro Doria, Benjamin D. Humphreys, Kevin L. Duffin, Paolo Fiorina, Robert G. Nelson, Andrzej S. Krolewski
Publikováno v:
Sci Transl Med
Circulating proteins associated with transforming growth factor-β (TGF-β) signaling are implicated in the development of diabetic kidney disease (DKD). No study has comprehensively examined which of these proteins are involved in the pathogenesis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ce2222672f29b59c3bc4fbd3fc7550
https://pubmed.ncbi.nlm.nih.gov/35947673
https://pubmed.ncbi.nlm.nih.gov/35947673
Autor:
Caterina Pipino, Andrzej S. Krolewski, C. Ronald Kahn, Meda E. Pavkov, Helen C. Looker, Bozena Krolewski, Behzad Najafian, Rohit N. Kulkarni, Michael Mauer, Zaipul I. Md Dom, Marcus G. Pezzolesi, Pierre-Jean Saulnier, Viji Nair, Matthias Kretzler, Monika A. Niewczas, Eiichiro Satake, Robert G. Nelson, Manoj K. Gupta, Hiroki Kobayashi, Alessandro Doria, Kristina O’Neil, Kevin L. Duffin, Jonathan M. Wilson, Markus Bitzer, Katsuhito Ihara
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Mechanisms underlying the pro gression of diabetic kidney disease to ESKD are not fully understood. METHODS: We performed global microRNA (miRNA) analysis on plasma from two cohorts consisting of 375 individuals with type 1 and type 2 dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26743561cbc88e3c5896747d85c25e2c
https://doi.org/10.1681/asn.2021010105
https://doi.org/10.1681/asn.2021010105
Autor:
Christopher A. Simeone, Joseph L. Wilkerson, Annelise M. Poss, James A. Banks, Joseph V. Varre, Jose Lazaro Guevara, Edgar Javier Hernandez, Bushra Gorsi, Donald L. Atkinson, Tursun Turapov, Scott G. Frodsham, Julio C. Fierro Morales, Kristina O’Neil, Barry Moore, Mark Yandell, Scott A. Summers, Andrzej S. Krolewski, William L. Holland, Marcus G. Pezzolesi
Publikováno v:
NPJ genomic medicine. 7(1)
Adiponectin, encoded by ADIPOQ, is an insulin-sensitizing, anti-inflammatory, and renoprotective adipokine that activates receptors with intrinsic ceramidase activity. We identified a family harboring a 10-nucleotide deletion mutation in ADIPOQ that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7575e283299106a2e60122c72e7f780f
https://pubmed.ncbi.nlm.nih.gov/35869090
https://pubmed.ncbi.nlm.nih.gov/35869090
Autor:
Rachel G. Miller, Erkka Valo, Jani K. Haukka, Tina Costacou, Barbara E.K. Klein, Beata Gyorgy, Joseph V. Bonventre, Katalin Susztak, Hillary A. Keenan, James H. Warram, Marlon Pragnell, Ivan G. Shabalin, Andrew D. Paterson, Stephen S. Rich, Takaharu Ichimura, Jingjing Cao, Suna Onengut-Gumuscu, Ronald Klein, Kristina O’Neil, Eiichiro Satake, Marcus G. Pezzolesi, Josyf C. Mychaleckyj, Niina Sandholm, Christian Dina, Andrzej T. Galecki, George L. King, Trevor J. Orchard, Samy Hadjadj, Per-Henrik Groop, Adam M. Smiles, Carol Forsblom, Andrzej S. Krolewski, David-Alexandre Trégouët, Tarunveer S. Ahluwalia, Peter Rossing, Ron Korstanje
Publikováno v:
Journal of the American Society of Nephrology
Journal of the American Society of Nephrology, American Society of Nephrology, 2021, 32 (10), pp.2634-2651. ⟨10.1681/ASN.2020101457⟩
Journal of the American Society of Nephrology, American Society of Nephrology, 2021, 32 (10), pp.2634-2651. ⟨10.1681/ASN.2020101457⟩
Background Rare variants in gene coding regions likely have a greater impact on disease-related phenotypes than common variants through disruption of their encoded protein. We searched for rare variants associated with onset of end stage kidney disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d8ebafcd82a8106854f67bac0a578d
http://hdl.handle.net/20.500.12278/123983
http://hdl.handle.net/20.500.12278/123983
Autor:
Hiroki Kobayashi, Helen C. Looker, Eiichiro Satake, Pierre Jean Saulnier, Zaipul I. Md Dom, Kristina O’Neil, Katsuhito Ihara, Bozena Krolewski, Andrzej T. Galecki, Monika A. Niewczas, Jonathan M. Wilson, Alessandro Doria, Kevin L. Duffin, Robert G. Nelson, Andrzej S. Krolewski
Publikováno v:
Kidney international. 102(2)
This study applies a large proteomics panel to search for new circulating biomarkers associated with progression to kidney failure in individuals with diabetic kidney disease. Four independent cohorts encompassing 754 individuals with type 1 and type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82ea919a5fb21d1bd30dfcbcbb575a3
https://pubmed.ncbi.nlm.nih.gov/35870813
https://pubmed.ncbi.nlm.nih.gov/35870813
Autor:
Simon T. Dillon, Jill A. Willency, Andrzej S. Krolewski, Eiichiro Satake, Kevin L. Duffin, Jonathan M. Wilson, Katsuhito Ihara, Hiroki Kobayashi, Marlon Pragnell, Towia A. Libermann, Kristina O’Neil, Zaipul I. Md Dom, Bozena Krolewski, Jan Skupien
Publikováno v:
Sci Transl Med
Diabetic kidney disease (DKD) and its major clinical manifestation, progressive renal decline that leads to end-stage renal disease (ESRD), are a major health burden for individuals with diabetes. The disease process that underlies progressive renal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6934c58b9b0ea1833405989d83273e
https://doi.org/10.1126/scitranslmed.abd2699
https://doi.org/10.1126/scitranslmed.abd2699
Autor:
Kristina O’Neil, Eiichiro Satake, Andrzej S. Krolewski, Caterina Pipino, Bozena Krolewski, Zaipul I. Md Dom
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
We recently identified a kidney risk inflammatory signature (KRIS), comprising 6 TNF receptors (including TNFR1 and TNFR2) and 11 inflammatory proteins. Elevated levels of these proteins in circulation were strongly associated with risk of the develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ddafb5b24a6728fa50113da6cd21c81
https://doi.org/10.1038/s41598-021-90496-w
https://doi.org/10.1038/s41598-021-90496-w
Autor:
Hiroki Kobayashi, Andrzej S. Krolewski, Monika A. Niewczas, Katsuhito Ihara, Kristina O’Neil, Narges M. Rashidi, Bozena Krolewski, Jan Skupien, Zaipul I. Md Dom, Eiichiro Satake
This study comprehensively evaluated the association between known circulating tumor necrosis factor (TNF) superfamily ligands and receptors and the development of early progressive kidney decline (PKD) leading to end-stage kidney disease (ESKD) in T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654b9adadadee7df851eaba096ba758b
https://ruj.uj.edu.pl/xmlui/handle/item/267368
https://ruj.uj.edu.pl/xmlui/handle/item/267368