Výsledky vyhledávání - "A. S. Izotova"

Akademický článek

TECHNICAL EFFICIENCY OF REGIONS AS A TOOL FOR INCREASING THE COMPETITIVENESS OF TERRITORIES THROUGH THE STRATEGY OF TECHNOLOGICAL ARBITRAGE (CATCHING-UP STRATEGY)

Autor: Natalya O. Chistyakova, Alexander A. Mikhalchuk, Valerya V. Tatarnikova, Ekaterina A. Akerman, Anastasiya S. Izotova

Publikováno v: Векторы благополучия: экономика и социум, Vol 45, Iss 2, Pp 179-193 (2022)

The article is devoted to the problem of increasing the competitiveness of regions through the application of the technology arbitrage strategy at the macro-regional level. The paper explores the possibilities of applying the imitation strategy for f

Externí odkaz: https://doaj.org/article/dce53540a6df494aaa0fef8e69612f97

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Analytical use of multi-protein fluorescence resonance energy transfer to demonstrate membrane-facilitated interactions within cytokine receptor complexes

Autor: Christopher D. Krause, Sidney Pestka, Lara S. Izotova

Publikováno v: Cytokine

Experiments measuring Fluorescence Resonance Energy Transfer (FRET) between cytokine receptor chains and their associated proteins led to hypotheses describing their organization in intact cells. These interactions occur within a larger protein compl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcccc33756f32bacf4b6df8d147bcf58
https://doi.org/10.1016/j.cyto.2013.05.008

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Improving the spectral analysis of fluorescence resonance energy transfer in live cells: Application to interferon receptors and Janus kinases

Autor: Gina DiGioia, Sidney Pestka, Christopher D. Krause, Lara S. Izotova

Publikováno v: Cytokine. 64:272-285

The observed Fluorescence Resonance Energy Transfer (FRET) between fluorescently labeled proteins varies in cells. To understand how this variation affects our interpretation of how proteins interact in cells, we developed a protocol that mathematica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3a77e51279b7323a9cdaaf83178127
https://doi.org/10.1016/j.cyto.2013.05.026

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The IL-10R2 Binding Hot Spot on IL-22 is Located on the N-terminal Helix and is Dependent on N-linked Glycosylation

Autor: Naomi J. Logsdon, Sidney Pestka, Jennifer C. Allman, Brandi C. Jones, Lara S. Izotova, Mark R. Walter, Barbara Schwartz

Publikováno v: Journal of Molecular Biology. 342:503-514

IL-22 is a class 2 alpha-helical cytokine involved in the generation of inflammatory responses. These activities require IL-22 to engage the cell surface receptors IL-22R1 and the low-affinity signaling molecule IL-10R2. IL-10R2 also interacts with f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dace2a5fc37d0b439b25804aa0c34e7f
https://doi.org/10.1016/j.jmb.2004.07.069

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Site-Specific 32P-Labeling of Cytokines, Monoclonal Antibodies, and Other Protein Substrates for Quantitative Assays and Therapeutic Application

Autor: William A. Clark, Doranelly Philipova, Lei Lin, Wei Wu, Lara S. Izotova, Sidney Pestka

Publikováno v: BioTechniques. 33:S76-S87

Radiolabeled proteins are used in a variety of laboratory applications as well as in radioimmunotherapy. This review focuses on methods that utilize genetic engineering to introduce exogenous phosphorylation sites into proteins. Protein kinase substr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eaf92d6131caa092275049761b9f1b4e
https://doi.org/10.2144/oct0209

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Identification, Cloning, and Characterization of a Novel Soluble Receptor That Binds IL-22 and Neutralizes Its Activity

Autor: Raymond P. Donnelly, Olga V. Mirochnitchenko, Lara S. Izotova, Sidney Pestka, Harold Dickensheets, Elena Esterova, Sergei V. Kotenko

Publikováno v: The Journal of Immunology. 166:7096-7103

With the use of a partial sequence of the human genome, we identified a gene encoding a novel soluble receptor belonging to the class II cytokine receptor family. This gene is positioned on chromosome 6 in the vicinity of the IFNGR1 gene in a head-to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f2a9233f040c245ffcfa235f41a406
https://doi.org/10.4049/jimmunol.166.12.7096

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Identification of the Functional Interleukin-22 (IL-22) Receptor Complex

Autor: Harold Dickensheets, Sergei V. Kotenko, Sidney Pestka, Lara S. Izotova, Elena Esterova, Raymond P. Donnelly, Olga V. Mirochnitchenko

Publikováno v: Journal of Biological Chemistry. 276:2725-2732

Interleukin-10 (IL-10)-related T cell-derived inducible factor (IL-TIF; provisionally designated IL-22) is a cytokine with limited homology to IL-10. We report here the identification of a functional IL-TIF receptor complex that consists of two recep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6f57e0d1bee7b85e9f6946d5a8a3042
https://doi.org/10.1074/jbc.m007837200

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Cloning, expression and initial characterisation of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)

Autor: Nancy Vazquez, J Eskdale, Olga Mirochnitchenko, Jon Peat, Harold Dickensheets, Sidney Pestka, Serguei V. Kotenko, Lara S. Izotova, Raymond P. Donnelly, G Gallagher

Publikováno v: Genes & Immunity. 1:442-450

Interleukin-10 (IL-10) is a pleiotropic cytokine with important immunoregulatory functions whose actions influence activities of many of the cell-types in the immune system. We report here identification and cloning of a gene and corresponding cDNAs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbdc7a8c6e07ed3d37a4eb46acaf03f
https://doi.org/10.1038/sj.gene.6363714

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