Zobrazeno 1 - 10
of 291
pro vyhledávání: '"A. S. Hume"'
Autor:
Irina Petrache, Elisabet Pujadas, Aditya Ganju, Karina A. Serban, Alexander Borowiec, Beatrice Babbs, Irina A. Bronova, Nicholas Egersdorf, Patrick S. Hume, Khushboo Goel, William J. Janssen, Evgeny V. Berdyshev, Carlos Cordon-Cardo, Richard Kolesnick
Publikováno v:
JCI Insight, Vol 8, Iss 10 (2023)
The pathogenesis of the marked pulmonary microvasculature injury, a distinguishing feature of COVID-19 acute respiratory distress syndrome (COVID-ARDS), remains unclear. Implicated in the pathophysiology of diverse diseases characterized by endotheli
Externí odkaz:
https://doaj.org/article/941d1f0f2b0b4a3796435b73218fab88
Autor:
Irina Petrache, Arnav Gupta, Patrick S. Hume, Tanner Rivera, Kelly S. Schweitzer, Hong Wei Chu
Publikováno v:
Comprehensive Physiology. :4617-4630
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::177235a2ca5b5eb0e77e193a1dc80e88
https://doi.org/10.1002/cphy.c220022
https://doi.org/10.1002/cphy.c220022
Autor:
Patrick S. Hume, Jazalle McClendon, Katrina W. Kopf, Julie W. Harral, Joanna M. Poczobutt, Alexandra L. McCubbrey, Bradford J. Smith, Peter M. Henson, Susan M. Majka, Irina Petrache, William J. Janssen
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 323:L391-L399
The pathogenesis of chronic obstructive pulmonary disease (COPD), a prevalent disease primarily caused by cigarette smoke exposure, is incompletely elucidated. Studies in humans and mice have suggested that hypoxia-inducible factor-1α (HIF-1α) may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b4e0cbf8b8ed9730a30f9a5660570a
https://doi.org/10.1152/ajplung.00491.2021
https://doi.org/10.1152/ajplung.00491.2021
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 323:L281-L296
Supportive mechanical ventilation is a necessary lifesaving treatment for acute respiratory distress syndrome (ARDS). This intervention often leads to injury exacerbation by ventilator-induced lung injury (VILI). Patterns of injury in ARDS and VILI a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a6bac247ffa98a60f7aa0ec4e063d5
https://doi.org/10.1152/ajplung.00207.2021
https://doi.org/10.1152/ajplung.00207.2021
Autor:
Rachel Blomberg, Kayla Sompel, Caroline Hauer, Brisa Peña, Jennifer Driscoll, Patrick S. Hume, Daniel T. Merrick, Meredith A. Tennis, Chelsea M. Magin
Publikováno v:
bioRxiv
Lung cancer is the leading global cause of cancer-related deaths. Although smoking cessation is the best preventive action, nearly 50% of all lung cancer diagnoses occur in people who have already quit smoking. Research into treatment options for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e856cdfd22445853c02694ff455847
https://europepmc.org/articles/PMC10055140/
https://europepmc.org/articles/PMC10055140/
Autor:
William H. Palmer, Laura Ann Leaton, Ana Campos Codo, Patrick S. Hume, Bergren Crute, Matthew Stone, Adrie van Bokhoven, Richard P. Tobin, Martin D. McCarter, William J. Janssen, James Roest, Shiying Zhu, Jan Petersen, Julian P. Vivian, Jamie Rossjohn, John Trowsdale, Andrew Getahun, John Cambier, Liyen Loh, Paul J. Norman
Most human killer cell immunoglobulin-like receptors (KIR) are expressed by Natural Killer (NK) cells and recognize HLA class I molecules as ligands. Uniquely, KIR3DL3 is a conserved but polymorphic inhibitory KIR recognizing a B7 family ligand, HHLA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca09eab4ce8449a4e1b260f2e4e4c9ee
https://doi.org/10.1101/2022.08.17.503789
https://doi.org/10.1101/2022.08.17.503789
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2506
Pulmonary macrophages are heterogeneous. Distinct populations of resident tissue macrophages exist in the lung airspace and tissue compartments during homeostasis. During inflammation, these are joined by monocyte-derived recruited macrophages. Flow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0e06671a17ef664f2dc6eda3b21703c
https://pubmed.ncbi.nlm.nih.gov/35771477
https://pubmed.ncbi.nlm.nih.gov/35771477
Autor:
K. Fujiwara, R. Kristeleit, S. Ghamande, M-C. Lim, C. Parkinson, M. Morgan, M.K. Wilson, A. Oaknin, J. Buscema, P. Bessette, D. Lorusso, F. Ueland, T. Safra, J.N. Barlin, F. Marmé, T.J. Herzog, I.A. McNeish, S. Goble, S. Hume, B.J. Monk
Publikováno v:
Annals of Oncology. 33:S1505-S1506
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbffcef08ff348e4f4bb4b4bef6bd6b6
https://doi.org/10.1016/j.annonc.2022.10.214
https://doi.org/10.1016/j.annonc.2022.10.214
Autor:
R. Kristeleit, S. Ghamande, M-C. Lim, C. Parkinson, M. Morgan, M. Wilson, A. Oaknin, J. Buscema, P. Bessette, D. Lorusso, F. Ueland, T. Safra, J. Barlin, F. Marmé, T.J. Herzog, I. McNeish, S. Goble, S. Hume, K. Fujiwara, B.J. Monk
Publikováno v:
Annals of Oncology. 33:S786-S787
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::770e532ae147619d7f7aa2e6d05487f6
https://doi.org/10.1016/j.annonc.2022.07.655
https://doi.org/10.1016/j.annonc.2022.07.655
Autor:
Sophie L. Gibbings, Bradford J. Smith, Peter M. Henson, William J. Janssen, Douglas Curran-Everett, Patrick S. Hume, Claudia Jakubzick, Rubin M. Tuder
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 201:1209-1217
Rationale: Interstitial macrophages (IMs) and airspace macrophages (AMs) play critical roles in lung homeostasis and host defense, and are central to the pathogenesis of a number of lung diseases. ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cf6b703297f674b9edcfbc6a6b8b814
https://doi.org/10.1164/rccm.201911-2105oc
https://doi.org/10.1164/rccm.201911-2105oc