Dual Versus Single Oxygenated Hypothermic Machine Perfusion of Porcine Livers: Impact on Hepatobiliary and Endothelial Cell Injury

Autor: Yvonne de Vries, MD, PhD, Isabel M. A. Brüggenwirth, BSc, Shanice A. Karangwa, MD, Fien A. von Meijenfeldt, BSc, Otto B. van Leeuwen, PhD, Laura C. Burlage, MD, PhD, Iris E. M. de Jong, MD, Annette S. H. Gouw, MD, PhD, Vincent E. de Meijer, MD, PhD, Ton Lisman, PhD, Robert J. Porte, MD, PhD

Publikováno v: Transplantation Direct, Vol 7, Iss 9, p e741 (2021)

Background. Hypothermic oxygenated machine perfusion (HOPE) reduces ischemia-reperfusion injury of donor livers and is increasingly used in clinical transplantation. However, it remains unclear whether perfusion via the portal vein alone (HOPE) or vi

Externí odkaz: https://doaj.org/article/7f0f666f4ffd4df4b0ba053029a14e60

B Cells as Prognostic Biomarker After Surgery for Colorectal Liver Metastases

Autor: Joost Hof, Lydia Visser, Diederik J. Höppener, Pieter M. H. Nierop, Miente M. Terpstra, Annette S. H. Gouw, Dirk J. Grünhagen, Cornelis Verhoef, Rolf H. Sijmons, Koert P. de Jong, Klaas Kok

Publikováno v: Frontiers in Oncology, Vol 10 (2020)

Background: The aim of this study was to identify more accurate variables to improve prognostication of individual patients with colorectal liver metastases (CRLM). Clinicopathological characteristics only partly explain the large range in survival r

Externí odkaz: https://doaj.org/article/f940bda3b01745c59d98154ff7af8a56

Hepatocellular adenoma: what we know, what we do not know, and why it matters

Autor: Christine Sempoux, Charles Balabaud, Paulette Bioulac-Sage, Annette S. H. Gouw

Publikováno v: Histopathology. 80:878-897

In the last two decades there has been significant progress in research on and diagnosis of hepatocellular adenoma (HCA), resulting in the establishment of a molecular and immunohistological HCA classification. This review aims to fine-tune the curre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079e7a9e544344ec8ea581897bcf2dbc
https://doi.org/10.1111/his.14605

Malignant Transformation of an HNF1a-Inactivated Hepatocellular Adenoma to Hepatocellular Carcinoma

Autor: Floris B. Poelmann, Annette S. H. Gouw, Robbert J. de Haas, Joost M. Klaase, Evelien W. Duiker, Hans Blokzijl, Joris T Hepkema

Publikováno v: Case reports in gastroenterology, 14(3), 577-585
Case Reports in Gastroenterology, Vol 14, Iss 3, Pp 577-585 (2020)
Case Reports in Gastroenterology

Hepatocellular adenomas (HCA) are rare benign tumors of the liver, occurring predominantly in females using oral contraceptives. Our case describes a 66-year-old woman presenting with a palpable mass in her upper abdomen. Contrast-enhanced computed t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b5ddefc6158f704d242e39b44665b1
https://doi.org/10.1159/000510215

Innervation of the proximal human biliary tree

Autor: Paulette Bioulac-Sage, Annette S. H. Gouw, Alexander Kofman, Charles Balabaud, Jason Reidy, John Qualter, Jon Osbeck, Dina Tiniakos, Neil D. Theise, Antonela C. Zanchi, Henry J. Feldman

Publikováno v: Virchows Archiv, 477(3), 385-392. SPRINGER

The autonomic nervous system plays a role in a variety of liver regenerative and metabolic functions, including modulating bile secretion and cholangiocyte and hepatobiliary progenitors of the canals of Hering. However, the nature and location of ner

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6fbeab6c8207f37455423f9ed00f11e
https://research.rug.nl/en/publications/7882101c-43c0-43d4-8137-3f2825fd0bc2