Effectiveness and safety of empegfilgrastim (Extimia®) in patients with solid tumors receiving cytotoxic therapy: final results of the DEFENDOR study

Autor: Anton V. Snegovoy, Inessa B. Kononenko, Irina M. Radiukova, Svetlana A. Orlova, Alexander V. Sultanbaev, Daria M. Dubovichenko, Aleksandr S. Dergunov, Aleksandra F. Saidullaeva, Nadezhda N. Repina, Iuliia A. Gronskaia, Elena I. Rossokha, Tatiana V. Starostina, Oksana V. Akimova, Iuliia A. Vasil'eva, Zarina A. Godzhieva, Ol'ga Iu. Garanina, Khava I. Gorchkhanova, Iuliia S. Machekhina, Aleksandra S. Gracheva, Anastasiia E. Danilova, Tat'iana N. Dmitrakova, Vadim N. Dmitriev, Marina V. Dmitrochenko, Olga V. Dylinova, Viktoriia O. El'kova, Alla V. Zhelezniak, Irina V. Zubova, Aleksandr N. Ivanov, Liliia P. Kaleikina, Iuliia V. Komoza, Dmitrii N. Korolev, Liudmila N. Lebedeva, Andrei A. Lebedinets, Naira N. Mamedguseinova, Valeriia S. Miagkova, Elena I. Matiushina, Kristina V. Narovenkova, Valentina M. Nikolaeva, Denis V. Novikov, Galina E. Polonskaia, Olesia V. Rebrina, Mariia A. Safronova, Anna S. Semenova, Inessa A. Semenova, Roman A. Skotnikov, Ekaterina P. Solov'eva, Anna N. Tat'ianenko, Antonina A. Teterich, Vladimir N. Timin, Irina A. Tolmacheva, Iana A. Tiugina, Aleksandra V. Khodkevich, Fatima V. Tsarakhova, Iana S. Chapko, Margarita M. Shegurova, Nadezhda R. Shakurova, Anna I. Shalina, Elena A. Shumilkina, Daria V. Iakuba, Tansylu M. Ibragimova, Polina S. Feoktistova, Irina V. Sorokina, Anna M. Berezina, Polina V. Kiseleva, Olga N. Mironenko, Oxana N. Prosianikova

Publikováno v: Современная онкология, Vol 26, Iss 2, Pp 159-171 (2024)

Aim. To evaluate the effectiveness and safety of Extimia® (empegfilgrastim, JSC "BIOCAD") in reducing the frequency, duration of neutropenia, the incidence of febrile neutropenia (FN) and infections caused by FN in patients with solid tumors receivi

Externí odkaz: https://doaj.org/article/cbf44cb884d749adae40ccde298bbf78

Final data on the efficacy of the FORA study (FOrteca Real practice Assessment): a multicenter prospective observational study on the real-world efficacy of prolgolimab in patients with metastatic melanoma in Russia

Autor: Kristina V. Orlova, Mikhail Iu. Fedyanin, Konstantin E. Simanenkov, Aleksandr S. Dergunov, Petr R. Goldshmidt, Aleksandra F. Saydullaeva, Darya V. Bogacheva, Marina A. Yavorskaya, Artur Z. Azanov, Alexander A. Fedenko, Larisa V. Bolotina, Tatyana I. Deshkina, Kseniya G. Babina, Ekaterina A. Kuzevanova, Liudmila G. Zhukova, Polina S. Feoktistova, Natalya I. Polshina, Ekaterina V. Peganova, Valentina E. Shikina, Maksim M. Sobolev, Oleg V. Mironov, Vera A. Vaschenko, Mariya M. Ershova, Agniya O. Mezhueva, Svetlana A. Orlova, Denis A. Tantsyrev, Darya K. Taskina, Antonina A. Teterich, Elena V. Karabina, Yuliya V. Kostalanova, Marina V. Bogacheva, Natalia V. Zhukova, Rashida V. Orlova, Maksim V. Zinkevich, Aleksandr I. Kazmin, Mikhail V. Volkonskiy, Liya M. Voronkova, Anastasiya S. Karpova, Mikhail L. Maleyko, Mariya N. Gorshenina, Elena I. Kryuchkova, Fedor V. Moiseenko, Yuliya I. Murzina, Shamil I. Musin, Andrey N. Ogloblin, Mariya S. Perminova, Regina A. Dumbrava, Sergey A. Emelyanov, Svetlana A. Protsenko, Alexander V. Sultanbaev, Anna V. Tarasova, Elena B. Shakhnovich, Marina V. Demchenkova, Yuliya A. Lozovskaya, Khedi S. Musaeva, Elena M. Pavlova, Roman A. Skotnikov, Vera V. Chernova, Angelina S. Chichkanova, Adina M. Akhmatova, Marina A. Zafirova, Andrey A. Mischenko, Elena N. Ovsienko, Viktoriya A. Petrukhnenko, Oksana A. Syusyukaylova, Yana A. Tyugina, Elena A. Shumilkina, Daniil L. Stroyakovskiy, Aleksandr N. Yurchenkov, Pavel L. Baldin, Anastasiya S. Belova, Olga V. Diduk, Elena A. Konovalova, Lyudmila N. Lebedeva, Yaroslav A. Li, Viktoriya V. Mashtapa, Yana A. Mironenkova, Kristina V. Narovenkova, Olga A. Pavlikova, Elvira L. Parsadanova, Irina S. Pimonova, Anna A. Ruzhnikova, Irina D. Sivunova, Ekaterina P. Soloveva, Maksim I. Sosnin, Kh. Toita Temirsultanova, Makhabbat Zh. Tyulegenova, Aleksandra V. Khodkevich, Nadezhda R. Shakurova, Sureya N. Efendieva, Karine L. Avagimyan, Ekaterina Р. Anokhina, Mariya I. Antoshkina, Stanislav M. Borzyanitsa, Samir K. Dzhentemirov, Marina V. Dmitrochenko, Alla V. Zheleznyak, Yuliya V. Komoza, Aleksandr S. Kopanev, Tatyana I. Kornienko, Margarita A. Krasilnikova, Darya A. Lukhmanova, Natalya S. Mazur, Polina M. Markina, Zhargal S. Mitapov, Svetlana N. Osodoeva, Irina A. Prokopenko, Irina M. Radyukova, Madina S. Ramazanova, Alfiya R. Safarova, Mariya A. Safronova, Khalimat M. Khabrieva, Natalya S. Tsygankova, Kseniya V. Chermakova, Tatyana A. Chirkova, Igor V. Samoylenko, Valeria V. Nazarova, Angelina E. Akhmetyanova, Lev V. Demidov

Publikováno v: Современная онкология, Vol 26, Iss 1, Pp 20-34 (2024)

Background. Prior to the introduction of new agents — immune checkpoint inhibitors — for inoperable and/or metastatic melanoma (IMM), chemotherapy outcomes were generally poor. The median (Me) overall survival (OS) in IMM was no more than 6-9 mon

Externí odkaz: https://doaj.org/article/fff40d04a39d498ba7ec6262154c7020

Eribulin-trastuzumab combination in HER2-positive metastatic breast cancer: updated results from a Russian observational study

Autor: E. I. Kovalenko, E. V. Artamonova, L. V. Bolotina, L. A. Zhiliaeva, D. M. Ponomarenko, E. V. Karabina, G. Z. Mukhametshina, A. I. Khasanova, E. Yu. Ratner, A. R. Safarova, A. G. Manikhas, N. O. Popova, I. V. Evstigneeva, L. Yu. Vladimirova, L. V. Kramskaya, T. V. Karandeeva, I. R. Suslova, O. V. Romanchuk, V. E. Shikina, A. Yu. Povyshev, M. A. Osipov, E. M. Cherniakova, A. S. Dergunov, M. V. Volkonskiy, I. S. Chernov, I. E. Shumskaya, M. M. Fael, V. I. Garifullina, I. E. Gudkova

Publikováno v: Медицинский совет, Vol 0, Iss 20, Pp 36-46 (2021)

Introduction. The standard of 1st line treatment of HER2+ metastatic breast cancer (mBC) is double blockade with trastuzumab and pertuzumab + taxane, 2nd line – Trastuzumab-emtazine. There are no standards for further treatment, as well as the opti

Externí odkaz: https://doaj.org/article/ddfb182fcf6247f0b4a7bd188e53d850

Analysis of the efficacy and safety of eribulin therapy in patients with HR+/HER2- metastatic breast cancer pretreated with CDK4/6 inhibitors in real Russian practice

Autor: Inna P. Ganshina, Elena G. Ovchinnikova, Oksana M. Shalaeva, Svetlana V. Kuzmicheva, Alina N. Fedorova, Asiat I. Tekeeva, Alexander V. Sultanbaev, Elena V. Markizova, L G Zhukova, Ksenia S. Maistrenko, Svetlana A. Orlova, Irina V. Evstigneeva, Daniil L'vovich Stroyakovskiy, James J. Kolokolov, Olesya A. Kuchevskaya, Oksana N. Shirokova, Oksana I. Arapova, Elena V. Zueva, Anna V. Vasilevskaya, Tatyana A. Nersesova, Arshak A. Akopyan, Irina V. Kolyadina, Larisa Bolotina, Mariam Z. Yakubova, Sergey P. Medvedev, Alexandr S. Dergunov, Irina A. Shangina, Elvira A. Bobrova, Chulpan K. Valiakhmetova, Anna E. Storozhakova, Aleksei V. Emshanov, Natalia V. Fadeeva, Mikhail V. Volkonskiy, Yulia I. Merzlikina, Galina V. Antonova, Ivan A. Luev, Alisa R. Shumskikh, Natalia Yu. Samaneva, Elena Karabina, Natalia R. Abidova, Viktoria S. Egurenkova, Vasily V. Marfutov, Irina E. Gudkova, Lyubov Vladimirova, Olesya A. Stativko

Publikováno v: Современная онкология, Vol 23, Iss 1, Pp 68-76 (2021)

Relevance. Data on the efficacy of endocrine and chemotherapy regimens in patients with hormone-resistant metastatic breast cancer (mBC) after progression with CDK4/6 inhibitors are limited; the search for an effective therapy regimen in this clinica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb5294fb4dbd7b9369d65fe23e952c1
https://modernonco.orscience.ru/1815-1434/article/viewFile/70308/51242

FPGA-based convolutional layer implementation

Autor: A. K. Berzin, E. S. Dergunov

Publikováno v: Journal of Physics: Conference Series. 1680:012006

In this paper, several approaches to the implementation of a convolutional layer of a neural network on FPGAs for use in embedded systems are considered, as well as a number of optimizations necessary to speed up the operation of such a layer. At the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75fb4ef3053f7a0351757aad5d43f8f5
https://doi.org/10.1088/1742-6596/1680/1/012006