Zobrazeno 1 - 10
of 212
pro vyhledávání: '"A. S. Caravaca"'
Autor:
Osman Ahmed, April S. Caravaca, Maria Crespo, Wanmin Dai, Ting Liu, Qi Guo, Magdalena Leiva, Guadalupe Sabio, Vladimir S. Shavva, Stephen G. Malin, Peder S. Olofsson
Publikováno v:
Bioelectronic Medicine, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Background The liver is an important immunological organ and liver inflammation is part of the pathophysiology of non-alcoholic steatohepatitis, a condition that may promote cirrhosis, liver cancer, liver failure, and cardiovascular disease.
Externí odkaz:
https://doaj.org/article/9da48cf905954ac6b4d0687c31190809
Publikováno v:
Bioelectronic Medicine, Vol 6, Iss 1, Pp 1-8 (2020)
Abstract Atherosclerosis is a multifactorial chronic inflammatory disease that underlies myocardial infarction and stroke. Efficacious treatment for hyperlipidemia and hypertension has significantly reduced morbidity and mortality in cardiovascular d
Externí odkaz:
https://doaj.org/article/2574091e357740c8a9679f06512e5fe3
Autor:
Ashok Kumar Kumawat, Mulugeta M. Zegeye, Geena Varghese Paramel, Roland Baumgartner, Anton Gisterå, Obed Amegavie, Sanna Hellberg, Hong Jin, April S. Caravaca, Leif Å. Söderström, Lindvi Gudmundsdotter, Fredrik Y. Frejd, Liza U. Ljungberg, Peder S. Olofsson, Daniel F. J. Ketelhuth, Allan Sirsjö
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
The balance between pro- and anti-inflammatory cytokines released by immune and non-immune cells plays a decisive role in the progression of atherosclerosis. Interleukin (IL)-17A has been shown to accelerate atherosclerosis. In this study, we investi
Externí odkaz:
https://doaj.org/article/a008b8877cff40138fe7b07965ae20bc
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
Crohn’s disease is a chronic, idiopathic condition characterized by intestinal inflammation and debilitating gastrointestinal symptomatology. Previous studies of inflammatory bowel disease (IBD), primarily in colitis, have shown reduced inflammatio
Externí odkaz:
https://doaj.org/article/cdd2d7d6cec44344b45cba39dbbfe01b
Autor:
Alessandro L. Gallina, Urszula Rykaczewska, Robert C. Wirka, April S. Caravaca, Vladimir S. Shavva, Mohamad Youness, Glykeria Karadimou, Mariette Lengquist, Anton Razuvaev, Gabrielle Paulsson-Berne, Thomas Quertermous, Anton Gisterå, Stephen G. Malin, Laura Tarnawski, Ljubica Matic, Peder S. Olofsson
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Objectives and Aims: Vascular smooth muscle cells (VSMCs) are key constituents of both normal arteries and atherosclerotic plaques. They have an ability to adapt to changes in the local environment by undergoing phenotypic modulation. An improved und
Externí odkaz:
https://doaj.org/article/00172a729ab44f2ab228b984782249c7
Autor:
Padinhare Cholakkal Harikesh, Chi-Yuan Yang, Han-Yan Wu, Silan Zhang, Mary J. Donahue, April S. Caravaca, Jun-Da Huang, Peder S. Olofsson, Magnus Berggren, Deyu Tu, Simone Fabiano
Publikováno v:
Nature Materials. 22:242-248
Biointegrated neuromorphic hardware holds promise for new protocols to record/regulate signalling in biological systems. Making such artificial neural circuits successful requires minimal device/circuit complexity and ion-based operating mechanisms a
Autor:
April S. Caravaca, Alessandro L. Gallina, Laura Tarnawski, Kevin J. Tracey, Valentin A. Pavlov, Yaakov A. Levine, Peder S. Olofsson
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Neural reflexes regulate inflammation and electrical activation of the vagus nerve reduces inflammation in models of inflammatory disease. These discoveries have generated an increasing interest in targeted neurostimulation as treatment for chronic i
Externí odkaz:
https://doaj.org/article/86e0529f59b34732b2ba5ff9d509db20
Autor:
Laura Tarnawski, Vladimir S. Shavva, Eric J. Kort, Zhengbing Zhuge, Ingrid Nilsson, Alessandro L. Gallina, David Martínez-Enguita, Benjamin Heller Sahlgren, Matthew Weiland, April S. Caravaca, Staffan Schmidt, Ping Chen, Katarina Abbas, Fu-Hua Wang, Osman Ahmed, Michael Eberhardson, Anna Färnert, Eddie Weitzberg, Mika Gustafsson, Jan Kehr, Stephen G. Malin, Henrik Hult, Mattias Carlström, Stefan Jovinge, Peder S. Olofsson
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Endothelial dysfunction and impaired vasodilation are linked with adverse cardiovascular events. T lymphocytes expressing choline acetyltransferase (ChAT), the enzyme catalyzing biosynthesis of the vasorelaxant acetylcholine (ACh), regulate vasodilat
Autor:
Laura Tarnawski, Colin Reardon, April S. Caravaca, Mauricio Rosas-Ballina, Michael W. Tusche, Anna R. Drake, LaQueta K. Hudson, William M. Hanes, Jian Hua Li, William R. Parrish, Kaie Ojamaa, Yousef Al-Abed, Michael Faltys, Valentin A. Pavlov, Ulf Andersson, Sangeeta S. Chavan, Yaakov A. Levine, Tak W. Mak, Kevin J. Tracey, Peder S. Olofsson
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Macrophage cytokine production is regulated by neural signals, for example in the inflammatory reflex. Signals in the vagus and splenic nerves are relayed by choline acetyltransferase+ T cells that release acetylcholine, the cognate ligand for alpha7
Externí odkaz:
https://doaj.org/article/52bcfec8bc364d5ab8731c82b886af1a
Autor:
Alessondra T. Speidel, Phillip R. A. Chivers, Christopher S. Wood, Derrick A. Roberts, Inês P. Correia, April S. Caravaca, Yu Kiu Victor Chan, Catherine S. Hansel, Johannes Heimgärtner, Eliane Müller, Jill Ziesmer, Georgios A. Sotiriou, Peder S. Olofsson, Molly M. Stevens
Polyurethane-based hydrogels are relatively inexpensive and mechanically robust biomaterials with ideal properties for various applications, including drug delivery, prosthetics, implant coatings, soft robotics, and tissue engineering. In this report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc707be1b5409425b157bf8baaaef49
http://hdl.handle.net/10044/1/99987
http://hdl.handle.net/10044/1/99987