Výsledky vyhledávání - "A. S. Belloni"

Akademický článek

Endothelin‐1 Drives Epithelial‐Mesenchymal Transition in Hypertensive Nephroangiosclerosis

Autor: Teresa M. Seccia, Brasilina Caroccia, Francesca Gioco, Maria Piazza, Valentina Buccella, Diego Guidolin, Eugenia Guerzoni, Barbara Montini, Lucia Petrelli, Elisa Pagnin, Verdiana Ravarotto, Anna S. Belloni, Lorenzo A. Calò, Gian Paolo Rossi

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 7 (2016)

BackgroundTubulointerstitial fibrosis, the final outcome of most kidney diseases, involves activation of epithelial mesenchymal transition (EMT). Endothelin‐1 (ET‐1) activates EMT in cancer cells, but it is not known whether it drives EMT in the

Externí odkaz: https://doaj.org/article/ff41e15239f54c0faafbd589989fa82f

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Akademický článek

ALMS1-deficient fibroblasts over-express extra-cellular matrix components, display cell cycle delay and are resistant to apoptosis.

Autor: Elisabetta Zulato, Francesca Favaretto, Caterina Veronese, Stefano Campanaro, Jan D Marshall, Sara Romano, Anna Cabrelle, Gayle B Collin, Barbara Zavan, Anna S Belloni, Enrica Rampazzo, Jürgen K Naggert, Giovanni Abatangelo, Nicola Sicolo, Pietro Maffei, Gabriella Milan, Roberto Vettor

Publikováno v: PLoS ONE, Vol 6, Iss 4, p e19081 (2011)

Alström Syndrome (ALMS) is a rare genetic disorder (483 living cases), characterized by many clinical manifestations, including blindness, obesity, type 2 diabetes and cardiomyopathy. ALMS is caused by mutations in the ALMS1 gene, encoding for a lar

Externí odkaz: https://doaj.org/article/2274e355fc9f41a88d2f5d86a1327916

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Expression and functional role of the prorenin receptor in the human adrenocortical zona glomerulosa and in primary aldosteronism

Autor: Livia Lenzini, Lucia Petrelli, Juerg Nussberger, Teresa Maria Seccia, William E. Rainey, Giulio Ceolotto, Anna S. Belloni, C Recarti, Abril Gonzales-Campos, Brasilina Caroccia, Gian Paolo Rossi

Publikováno v: Journal of Hypertension, 33(5), 1014-1022. LIPPINCOTT WILLIAMS & WILKINS

Objectives: Prorenin can be detected in plasma of hypertensive patients. If detected in patients with primary aldosteronism could implicate prorenin in the development of primary aldosteronism. To address this issue, we measured the plasma prorenin l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ee6ca2e3e9699f32dc4b27abc1d32b
https://doi.org/10.1097/HJH.0000000000000504

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Lower Expression of the TWIK-Related Acid-Sensitive K+ Channel 2 (TASK-2) Gene Is a Hallmark of Aldosterone-Producing Adenoma Causing Human Primary Aldosteronism

Autor: Abril Gonzalez Campos, Maniselvan Kuppusamy, Livia Lenzini, Gian Paolo Rossi, Michael Bader, Silvia Ferraro, Ambrogio Fassina, William E. Rainey, Anna S. Belloni, Teresa Maria Seccia, Brasilina Caroccia, Ghizlane Skander

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 99:E674-E682

Context: The molecular mechanisms of primary aldosteronism, a common cause of human hypertension, are unknown, but alterations of K+ channels can play a key role. Objective: The objective of the study was to investigate the following: 1) the expressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13481380b2221cb11660f5e99937d4fc
https://doi.org/10.1210/jc.2013-2900

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Endothelin‐1 Drives Epithelial‐Mesenchymal Transition in Hypertensive Nephroangiosclerosis

Autor: Valentina Buccella, Elisa Pagnin, Verdiana Ravarotto, Diego Guidolin, Francesca Gioco, Barbara Montini, Brasilina Caroccia, Lucia Petrelli, Teresa Maria Seccia, Eugenia Guerzoni, Gian Paolo Rossi, Lorenzo A. Calò, Anna S. Belloni, Maria Piazza

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Background Tubulointerstitial fibrosis, the final outcome of most kidney diseases, involves activation of epithelial mesenchymal transition (EMT). Endothelin‐1 (ET‐1) activates EMT in cancer cells, but it is not known whether it drives EMT in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd212086b58d4ecfe5ba59cdaff33f4
https://doi.org/10.1161/jaha.116.003888

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Transcriptional regulation of hypoxia-inducible factor 1α by HIPK2 suggests a novel mechanism to restrain tumor growth

Autor: Diego Guidolin, Gianluca Bossi, Rosa Puca, Gabriella D'Orazi, Maurizio Onisto, Lavinia Nardinocchi, Carine Michiels, Anna S. Belloni, Ada Sacchi

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1793:368-377

HIPK2 has been implicated in restraining tumor progression by more than one mechanism, involving both its catalytic and transcriptional co-repressor functions. Starting from the finding that HIPK2 knockdown by RNA-interference (HIPK2i) induced signif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542a14c2656e84f02700de6b5391468a
https://doi.org/10.1016/j.bbamcr.2008.10.013

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Heterogeneity of Aldosterone-Producing Adenomas Revealed by a Whole Transcriptome Analysis

Autor: Teresa Maria Seccia, Luisa Giuliani, Enrico Aldighieri, Gastone G. Nussdorfer, Gian Paolo Rossi, Achille C. Pessina, Livia Lenzini, Paolo Bernante, Anna S. Belloni

Publikováno v: Hypertension. 50:1106-1113

Aldosterone-producing adenomas (APAs) are a common cause of arterial hypertension, but the underlying molecular mechanisms are unknown, although a transcriptional modulation of aldosterone synthase (CYP11B2) has been suggested. Aldosterone synthesis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecc8719458ebc7e18d3cf6a88b9c274
https://doi.org/10.1161/hypertensionaha.107.100438

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