Zobrazeno 1 - 10
of 342
pro vyhledávání: '"A. S. Arseniev"'
Autor:
F. D. Kornilov, A. V. Shabalkina, Cong Lin, P. E. Volynsky, E. F. Kot, A. L. Kayushin, V. A. Lushpa, M. V. Goncharuk, A. S. Arseniev, S. A. Goncharuk, Xiaohui Wang, K. S. Mineev
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Toll-like receptors (TLRs) play a key role in the innate immune system. Here, Kornilov et al. resolve the 3D structures of the membrane-associated parts of four TLRs to reveal properties of the juxta-membrane domain.
Externí odkaz:
https://doaj.org/article/baf24e9ec2e8437598a63374214adbcb
Autor:
Erik F. Kot, Sergey A. Goncharuk, María Luisa Franco, Daniel M. McKenzie, Alexander S. Arseniev, Andrea Benito-Martínez, Mario Costa, Antonino Cattaneo, Kalina Hristova, Marçal Vilar, Konstantin S. Mineev
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Neurotrophin receptors of the Trk family are involved in the regulation of brain development and neuroplasticity, and therefore can serve as targets for anti-cancer and stroke-recovery drugs, antidepressants, and many others. The structures
Externí odkaz:
https://doaj.org/article/215da1a995934cbf80876f433337845f
Autor:
Yulia A. Bogdanova, Ilya D. Solovyev, Nadezhda S. Baleeva, Ivan N. Myasnyanko, Anastasia A. Gorshkova, Dmitriy A. Gorbachev, Aidar R. Gilvanov, Sergey A. Goncharuk, Marina V. Goncharuk, Konstantin S. Mineev, Alexander S. Arseniev, Alexey M. Bogdanov, Alexander P. Savitsky, Mikhail S. Baranov
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract In this paper, we propose a fluorescence-lifetime imaging microscopy (FLIM) multiplexing system based on the fluorogen-activating protein FAST. This genetically encoded fluorescent labeling platform employs FAST mutants that activate the sam
Externí odkaz:
https://doaj.org/article/764e7772d88c4d09a2b7a1e5753e170f
Autor:
Vladislav A Lushpa, Marina V Goncharuk, Irina A Talyzina, Alexander S Arseniev, Eduard V Bocharov, Konstantin S Mineev, Sergey A Goncharuk
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0304997 (2024)
Toll-like receptors (TLRs) are key players in the innate immune system. Despite the great efforts in TLR structural biology, today we know the spatial structures of only four human TLR intracellular TIR domains. All of them belong to one of five subf
Externí odkaz:
https://doaj.org/article/9761a2e62c224787ad9499a872968cd1
Autor:
Marina V. Goncharuk, Nadezhda S. Baleeva, Dmitry E. Nolde, Alexey S. Gavrikov, Alexey V. Mishin, Alexander S. Mishin, Andrey Y. Sosorev, Alexander S. Arseniev, Sergey A. Goncharuk, Valentin I. Borshchevskiy, Roman G. Efremov, Konstantin S. Mineev, Mikhail S. Baranov
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Structural analyses guide the rational design of mutant fluorogen-activating proteins with enhanced fluorescence.
Externí odkaz:
https://doaj.org/article/9f5e4001803e45c99f3b5822fd1097f3
Autor:
Vladislav A. Lushpa, Marina V. Goncharuk, Cong Lin, Arthur O. Zalevsky, Irina A. Talyzina, Aleksandra P. Luginina, Daniil D. Vakhrameev, Mikhail B. Shevtsov, Sergey A. Goncharuk, Alexander S. Arseniev, Valentin I. Borshchevskiy, Xiaohui Wang, Konstantin S. Mineev
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Lushpa et al report the structure and dynamics of the TLR1 toll-interleukin like (TIR) cytoplasmic domain in both crystal and solution. They demonstrate that the TLR1 TIR domain is capable of specific binding of Zn with nanomolar affinity, which appe
Externí odkaz:
https://doaj.org/article/ba1903b9028f4b788d2c7b76bc761832
Autor:
Erik F. Kot, María L. Franco, Ekaterina V. Vasilieva, Alexandra V. Shabalkina, Alexander S. Arseniev, Sergey A. Goncharuk, Konstantin S. Mineev, Marçal Vilar
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104348- (2022)
Summary: Receptor tyrosine kinases (RTKs) are key players in development and several diseases. Understanding the molecular mechanism of RTK activation by its ligand could lead to the design of new RTK inhibitors. How the extracellular domain is coupl
Externí odkaz:
https://doaj.org/article/9b52a2d299164968b90fdd885a5b98ad
Autor:
Sergey A. Goncharuk, Lilya E. Artemieva, Kirill D. Nadezhdin, Alexander S. Arseniev, Konstantin S. Mineev
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Abstract The neurotrophin receptor p75NTR plays crucial roles in neuron development and regulates important neuronal processes like degeneration, apoptosis and cell survival. At the same time the detailed mechanism of signal transduction is unclear.
Externí odkaz:
https://doaj.org/article/93e81a0ed52f4a949f2c31ba9f7ec4c9
Autor:
Vladimir V. Britikov, Eduard V. Bocharov, Elena V. Britikova, Natalia I. Dergousova, Olga G. Kulikova, Anastasia Y. Solovieva, Nikolai S. Shipkov, Larisa A. Varfolomeeva, Tamara V. Tikhonova, Vladimir I. Timofeev, Eleonora V. Shtykova, Dmitry A. Altukhov, Sergey A. Usanov, Alexander S. Arseniev, Tatiana V. Rakitina, Vladimir O. Popov
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9969 (2022)
The search of a putative physiological electron acceptor for thiocyanate dehydrogenase (TcDH) newly discovered in the thiocyanate-oxidizing bacteria Thioalkalivibrio paradoxus revealed an unusually large, single-heme cytochrome c (CytC552), which was
Externí odkaz:
https://doaj.org/article/92fc435c03cf4dc5b2e1937cdccc14d3
Autor:
Vladislav V. Motov, Erik F. Kot, Alexandra V. Shabalkina, Sergey A. Goncharuk, Alexander S. Arseniev, Marina V. Goncharuk, Konstantin S. Mineev
Publikováno v:
Journal of Biomolecular NMR. 77:15-24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad984f051d006e3fde4a4733a78c8629
https://doi.org/10.1007/s10858-022-00408-x
https://doi.org/10.1007/s10858-022-00408-x