Zobrazeno 1 - 10
of 879
pro vyhledávání: '"A. S. Antonarakis"'
Autor:
Yun Cheng Sawa, Liwei Jia, Harris Krause, Margaret Meagher, Frederick Millard, Andrew Elliott, John T. Lafin, Christina Jamieson, Emmanuel S. Antonarakis, Anishka D’Souza, Krinio Giannikou, James F. Amatruda, Siamak Daneshmand, Rana R. McKay, Matthew Oberley, Chadi Nabhan, Aditya Bagrodia
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-6 (2024)
Abstract We sought to evaluate the genomic and transcriptomic landscapes in primary and metastatic germ cell tumors (GCTs; N = 138) to uncover factors that drive cisplatin resistance. Prevalence was calculated for platinum-resistant alterations (PRAs
Externí odkaz:
https://doaj.org/article/9c7c3fc28887449ba840d885f022b2bd
Autor:
Megan L. Ludwig, David Moline, Alec Horrmann, Ella Boytim, Gabrianne Larson, Ali T. Arafa, Masooma Sayeda, John R. Lozada, Hannah E. Bergom, Abderrahman Day, Sandhyarani Dasaraju, Scott M. Dehm, Paari Murugan, Justin Hwang, Justin M. Drake, Emmanuel S. Antonarakis
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract Metastases to the brain are rare in prostate cancer. Here, we describe a patient with two treatment-emergent metastatic lesions, one to the brain with neuroendocrine prostate cancer (NEPC) histology and one to the dural membrane of adenocarc
Externí odkaz:
https://doaj.org/article/9b28e7a9b567436c9bbec5f6ebc076a2
Publikováno v:
Progress in Orthodontics, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background The anatomic characteristics of the masticatory muscles differ across craniofacial skeletal patterns. Objective To identify differences in the anatomic characteristics of masticatory muscles across different sagittal and vertical
Externí odkaz:
https://doaj.org/article/c10101e02b8f478ea612a299940f1d6d
Publikováno v:
Journal of Hydrology: Regional Studies, Vol 53, Iss , Pp 101748- (2024)
Study area: Tana River Basin in Kenya. Study Focus: Flood-related impacts and losses have been rising. Therefore, understanding flood characteristics, drivers, and predictability is critical for informed decisions in the ongoing flood early warning (
Externí odkaz:
https://doaj.org/article/16978a1450984c58898c87aa9da9e835
Autor:
Mark C. Markowski, Mary-Ellen Taplin, Rahul Aggarwal, Laura A. Sena, Hao Wang, Hanfei Qi, Aliya Lalji, Victoria Sinibaldi, Michael A. Carducci, Channing J. Paller, Catherine H. Marshall, Mario A. Eisenberger, David E. Sanin, Srinivasan Yegnasubramanian, Carolina Gomes-Alexandre, Busra Ozbek, Tracy Jones, Angelo M. De Marzo, Samuel R. Denmeade, Emmanuel S. Antonarakis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Cyclic high-dose testosterone administration, known as bipolar androgen therapy (BAT), is a treatment strategy for patients with metastatic castration-resistant prostate cancer (mCRPC). Here, we report the results of a multicenter, single ar
Externí odkaz:
https://doaj.org/article/48b46172ca5a4aa0833d3da4c8f53c4c
Autor:
Hannah E. Bergom, Laura A. Sena, Abderrahman Day, Benjamin Miller, Carly D. Miller, John R. Lozada, Nicholas Zorko, Jinhua Wang, Eugene Shenderov, Francisco Pereira Lobo, Fernanda Caramella-Pereira, Luigi Marchionni, Charles G. Drake, Tamara Lotan, Angelo M. De Marzo, Justin Hwang, Emmanuel S. Antonarakis
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-9 (2024)
Abstract Patients with prostate cancer (PC) generally do not respond favorably to immune checkpoint inhibitors, which may be due to a low abundance of tumor-infiltrating lymphocytes even when mutational load is high. Here, we identified a patient who
Externí odkaz:
https://doaj.org/article/a63fc47e643a46939677c01b1b4e10df
Publikováno v:
Dentistry Journal, Vol 12, Iss 10, p 300 (2024)
This study aimed to investigate the influence of various patient-specific and bracket location-specific factors on bracket survival rates during comprehensive fixed appliance orthodontic treatment. A total of 197 patients (116 females, 81 males; mean
Externí odkaz:
https://doaj.org/article/3800bcc3971f4c9ab1073000c7a748cb
Autor:
Margaret Meagher, Harris Krause, Andrew Elliott, Alex Farrell, Emmanuel S. Antonarakis, Bruno Bastos, Elisabeth I. Heath, Christina Jamieson, Tyler F. Stewart, Aditya Bagrodia, Chadi Nabhan, Matt Oberley, Rana R. McKay, Amirali Salmasi
Publikováno v:
Cancer Medicine, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Background Non‐canonical WNT family (WNT5A pathway) signaling via WNT5A through ROR1 and its partner, ROR2, or Frizzled2 (FZD2) is linked to processes driving tumorigenesis and therapy resistance. We utilized a large dataset of urothelial
Externí odkaz:
https://doaj.org/article/a30f09f80e6e49edbc6a718dbeadeb97
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionRecently, an entity known as salivary duct carcinoma with rhabdoid features (SDC-RF) has been associated with somatic CDH1 mutations. Here we present the first known case report of conventional SDC occurring in the setting of a germline C
Externí odkaz:
https://doaj.org/article/c37eb444056e44dca1cd22c013b4f32c
Publikováno v:
Current Oncology, Vol 30, Iss 4, Pp 4246-4256 (2023)
The therapeutic landscape of several genitourinary malignancies has been revolutionized by the development of immune checkpoint inhibitors (ICIs); however, the utility of immunotherapies in prostate cancer has been limited, partly due to the immunolo
Externí odkaz:
https://doaj.org/article/52d8e5ded7684469971dc8a5c6e36a6f