Zobrazeno 1 - 10
of 346
pro vyhledávání: '"A. S. AbdElkhalek"'
Autor:
Ahmed Said, Amira S. AbdElkhalek, Mariam Sherief, Lydia Amir, Maysem Samy, Mariam S. Nabil, Gehan Safwat, Ayman A. Diab, Karima Nasraldin
Publikováno v:
Beni-Suef University Journal of Basic and Applied Sciences, Vol 13, Iss 1, Pp 1-9 (2024)
Abstract Background The active metabolite of vitamin A (retinol) is retinoic acid (RA). RA is essential for developing several organs as a signaling molecule that is tightly regulated during embryogenesis. We explored the teratogenic effects of RA on
Externí odkaz:
https://doaj.org/article/02349a7ff3e948e589f72819b2d0cba1
Autor:
Zeinab S. Abdelkhalek, Shadia M. Hussein, Iman G. Mahmoud, Areef Ramadan, Mona A. Kamel, Marian Y. Girgis, Mohamed A. Elmonem
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Maple Syrup Urine Disease (MSUD, OMIM# 248600) is an autosomal recessive inborn error of metabolism characterized by elevated branched chain amino acids (BCAA) leucine/isoleucine and valine in blood of affected children. The phenotypic and g
Externí odkaz:
https://doaj.org/article/8e0482058803486e94a6985389a539b4
Autor:
A. S. AbdElkhalek, N. Ghanem, M. G. Soliman, N. A. Abu El Naga, A. M. Kamel, H. A. Shedeed, K. A. El Bahrawy
Publikováno v:
Journal of the Indonesian Tropical Animal Agriculture, Vol 49, Iss 2, Pp 108-116 (2024)
Preservation of the livestock genetic makeup could be performed by application of in vitro fertilization (IVF) using spermatozoa collected from cauda epididymis. Therefore, this study as sessed the development of goat embryos following IVF of spermat
Externí odkaz:
https://doaj.org/article/0fc58b9347924b0188bac8b9e17ca8cf
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-14 (2024)
Abstract As pharmaceutical analysis progresses towards environmental sustainability, there is a growing need to enhance the safety and health conditions for analysts. Consequently, the incorporation of chemometrics into environmentally friendly analy
Externí odkaz:
https://doaj.org/article/e1ddc6cfb96d4837a22962d64b3301aa
Autor:
A. S. AbdElkhalek, M. G. Soliman, N. A. A. El Naga, K. A. El Bahrawy, A. M. Kamel, H. A. Shedeed, N. Ghanem
Publikováno v:
Journal of the Indonesian Tropical Animal Agriculture, Vol 49, Iss 1, Pp 78-90 (2024)
Goat production in Mediterranean countries is economically and socially significant. The study investigated the impact of hCG supplementation on the in vitro maturation, fertilization, and mitochondrial activity of goat oocytes. In total, 2356 good c
Externí odkaz:
https://doaj.org/article/f883984f6521492599939c4d8e8f8dc3
Autor:
Samy M. Ibrahim, Ahmed S. Abdelkhalek, Shaban A. A. Abdel-Raheem, Nada E. Freah, Nada H. El Hady, Nada K. Aidia, Nada A. Tawfeq, Nora I. Gomaa, Nora M. Fouad, Hager A. Salem, Hager M. Ibrahim, Mahmoud M. Sebai
Publikováno v:
Current Chemistry Letters, Vol 13, Iss 1, Pp 241-254 (2024)
2-Indolinone nucleus is considered one of a promising heterocyclic core in medicinal chemistry that showed numerous range of activity among which antimicrobial, antioxidant, antiviral, antitubercular and anticancer activities. Cancer targeting is sti
Externí odkaz:
https://doaj.org/article/d5cdb2b5c78f48c898b6981e6593246f
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Alkaptonuria (AKU) is a rare autosomal recessive metabolic disorder caused by pathogenic variants in the homogentisate 1,2-dioxygenase (HGD) gene. This leads to a deficient HGD enzyme with the consequent accumulation of homogentisic acid (HG
Externí odkaz:
https://doaj.org/article/ab9cb2c2a02a46ea89e293af1b1cbdfd
Autor:
Aisha M. Abdelkawy, Shifaa O. Alshammari, Hebat-Allah A. Hussein, Inas M. M. Abou El-Enain, Eman S. Abdelkhalek, Asmaa M. Radwan, Sahar K. M. Kenawy, Doaa A. M. Maaty, Nermine N. Abed, Shadia Sabry, Abeer Mohsen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The utilization of nanotechnology and biotechnology for enhancing the synthesis of plant bioactive chemicals is becoming increasingly common. The hairy root culture technique can be used to increase secondary metabolites such as tropane alka
Externí odkaz:
https://doaj.org/article/668d27465a5040c0a621a3568d30abe4
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
We designed and synthesised novel quinazolinone tethered phenyl urea derivatives (6a–p) that triple target the double mutant EGFRL858R/T790M, COX-2, and 15-LOX. Compounds (6e, 6d, 6j, 6m, and 6n) not only had low micromolar IC50 inhibitory activiti
Externí odkaz:
https://doaj.org/article/21decb402dab41299c88e29a35cb53ae
Autor:
Mahmoud A. Elfaky, Abrar K. Thabit, Khalid Eljaaly, Ayat Zawawi, Ahmed S. Abdelkhalek, Ahmad J. Almalki, Tarek S. Ibrahim, Wael A. H. Hegazy
Publikováno v:
Antibiotics, Vol 11, Iss 11, p 1585 (2022)
Salmonella enterica is a Gram-negative orofecal transmitted pathogen that causes a wide diversity of local and systemic illnesses. Salmonella enterica utilizes several interplayed systems to regulate its invasion and pathogenesis: namely, quorum sens
Externí odkaz:
https://doaj.org/article/08fe28ad718542b894e8007166c2cf5b