Zobrazeno 1 - 10
of 225
pro vyhledávání: '"A. S Kiselyov"'
Autor:
Roberta Poceviciute, Kenneth Mitchell, Angeliki Maria Nikolakopoulou, Suehyun K. Cho, Xiaobo Ma, Phillip Chen, Samantha Figueroa, Ethan J. Sarmiento, Aryan Singh, Oren Hartstein, William G. Loudon, Florent Cros, Alexander S. Kiselyov
Publikováno v:
Neuroimage: Reports, Vol 4, Iss 4, Pp 100218- (2024)
Viral vectors are an active area of research and development to treat diseases of the central nervous system (CNS). However, systemic delivery of large-molecular weight biologics is complicated by limited crossing of the blood-brain barrier, immunolo
Externí odkaz:
https://doaj.org/article/ce8f8bf6da8f40ba8226a4b8d6eae844
Autor:
Madlen Hotze, Miriam Gehrmann, Manuela Hessmann, Longbin Liu, Christoph Scheich, Kathrin Petersen, Nicole Hoeschen, Peter Johnson, Sabine Schaertl, Stefanie Jahn, Matthew R. Mills, Ignacio Munoz-Sanjuan, Alex S. Kiselyov, John Wityak, Anass Chiki, Vinod Khetarpal, Karsten Kottig, Gerhard Schmiedel, Galina Bursow, Stefanie Ladewig, Christopher J. Brown, Karola Berg-Rosseburg, Michael Prime, Sven Letschert, Andreas Ebneth, Jonathan Bard, Celia Dominguez, Frank Herrmann, Hilal A. Lashuel
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Scientific Reports
Scientific Reports
Huntington’s disease (HD) is caused by a CAG trinucleotide repeat expansion in the first exon of the huntingtin (HTT) gene coding for the huntingtin (HTT) protein. The misfolding and consequential aggregation of CAG-expanded mutant HTT (mHTT) under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a157f6eee06d07d3c18e1c6daf1e927b
https://doaj.org/article/9ab72a1e5e324d34b23c0110b93bbd78
https://doaj.org/article/9ab72a1e5e324d34b23c0110b93bbd78
This work introduces a model of immunotherapy treatment, namely the Bacillus Calmette-Guerin (BCG) vaccine, of type 1 diabetes (T1D). The model takes into consideration a clinically relevant interaction network between multiple immune cells and compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc31ab87c6c74493caf4860cc7fc721a
https://doi.org/10.1101/2021.09.02.458659
https://doi.org/10.1101/2021.09.02.458659
Autor:
Leonid D. Konyushkin, Delphine Gorses, Alexander V. Samet, Victor V. Semenov, Marina N. Semenova, Arkady A. Dudinov, Evgenii N Khodot, Mikhail M. Krayushkin, Eugenia A. Silyanova, Alexei S. Karpov, Boris V. Lichitsky, Thomas Radimerski, Alex S. Kiselyov, Andrey N. Komogortsev
Publikováno v:
ACS Combinatorial Science. 21:805-816
1,3-Substituted pyrazolo[3,4-b]pyridinones 11-18 were synthesized by a three-component condensation of Meldrum's acid with aryl aldehydes and 1,3-substituted 5-aminopyrazoles. Their biological activity was evaluated using the in vivo phenotypic sea u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa5709419948b56c9ec086d82231691b
https://doi.org/10.1021/acscombsci.9b00135
https://doi.org/10.1021/acscombsci.9b00135
Publikováno v:
IOP Conference Series: Earth and Environmental Science. 954:012077
The development and use of a set of highly automated agricultural machinery is necessary to ensure the effective involvement of agricultural land and the development of the land amelioration complex. The work analyzes the prospects for the developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4e7634845378b9bf1305a52138132ea
https://doi.org/10.1088/1755-1315/954/1/012077
https://doi.org/10.1088/1755-1315/954/1/012077
Autor:
Dmitry V. Demchuk, Alexander E. Varakutin, Anna S. Maksimenko, Alex S. Kiselyov, N. B. Chernysheva, Marina N. Semenova, V. P. Kislyi, Leonid D. Konyushkin, Eugenia A. Silyanova, Mikhail M. Raihstat, Victor V. Semenov, Dmitry V. Tsyganov, Alexander V. Samet
Publikováno v:
ACS Combinatorial Science. 20:700-721
A series of both novel and reported combretastatin analogues, including diarylpyrazoles, -isoxazoles, -1,2,3-triazoles, and -pyrroles, were synthesized via improved protocols to evaluate their antimitotic antitubulin activity using in vivo sea urchin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9201a126c9cf575c8c1bfb403f8a709
https://doi.org/10.1021/acscombsci.8b00113
https://doi.org/10.1021/acscombsci.8b00113
Publikováno v:
N.N. Priorov Journal of Traumatology and Orthopedics. 24:78-81
The review presents the factors that influence the outcomes of rehabilitation treatment after decompressive- stabilizing operations on the lumbar spine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b05fa5649aebb88e1cb6b889cf3d4372
https://doi.org/10.17816/vto201724478-81
https://doi.org/10.17816/vto201724478-81
Autor:
Jóhannes Reynisson, Marina N. Semenova, Leonid D. Konyushkin, Victor V. Semenov, Alex S. Kiselyov, Chatchakorn Eurtivong, Olga P. Atamanenko
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:658-664
A series of 3-amino-thieno[2,3-b]pyridines was prepared and tested in a phenotypic sea urchin embryo assay to identify potent and specific molecules that affect tubulin dynamics. The most active compounds featured a tricyclic core ring system with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06600b5b385f522dcb64e81bc1231f93
https://doi.org/10.1016/j.bmc.2016.11.041
https://doi.org/10.1016/j.bmc.2016.11.041
Publikováno v:
Вестник травматологии и ортопедии имени Н.Н. Приорова, Vol 0, Iss 4, Pp 78-81 (2017)
The review presents the factors that influence the outcomes of rehabilitation treatment after decompressivestabilizing operations on the lumbar spine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55fdef92e97f2961fae8174e1b19095
https://www.cito-vestnik.ru/jour/article/view/274
https://www.cito-vestnik.ru/jour/article/view/274
Autor:
Boris V, Lichitsky, Andrey N, Komogortsev, Arkady A, Dudinov, Mikhail M, Krayushkin, Evgenii N, Khodot, Alexander V, Samet, Eugenia A, Silyanova, Leonid D, Konyushkin, Alexei S, Karpov, Delphine, Gorses, Thomas, Radimerski, Marina N, Semenova, Alex S, Kiselyov, Victor V, Semenov
Publikováno v:
ACS combinatorial science. 21(12)
1,3-Substituted pyrazolo[3,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f31200d714d9547f6e1612bdcaa16a9e
https://pubmed.ncbi.nlm.nih.gov/31689077
https://pubmed.ncbi.nlm.nih.gov/31689077