Zobrazeno 1 - 10
of 41
pro vyhledávání: '"A. Sáez-Borderías"'
Autor:
P. Balsas, A. Esteve-Arenys, J. Roldán, L. Jiménez, V. Rodríguez, J. G. Valero, A. Chamorro-Jorganes, R. Puig de la Bellacasa, J. Teixidó, A. Matas-Céspedes, A. Moros, A. Martínez, E. Campo, A. Sáez-Borderías, J. I. Borrell, P. Pérez-Galán, D. Colomer, G. Roué
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-14 (2017)
Abstract Background Pharmacological inhibition of B cell receptor (BCR) signaling has recently emerged as an effective approach in a wide range of B lymphoid neoplasms. However, despite promising clinical activity of the first Bruton’s kinase (Btk)
Externí odkaz:
https://doaj.org/article/a3ba40f04c714fb78d9678c847e924a9
Autor:
Magri, Giuliana, Muntasell, Aura, Romo, Neus, Sáez-Borderías, Andrea, Pende, Daniela, Geraghty, Daniel E., Hengel, Hartmut, Angulo, Ana, Moretta, Alessandro, López-Botet, Miguel
Publikováno v:
In Blood 20 January 2011 117(3):848-856
Autor:
Anido, Judit, Sáez-Borderías, Andrea, Gonzàlez-Juncà, Alba, Rodón, Laura, Folch, Gerard, Carmona, Maria A., Prieto-Sánchez, Rosa M., Barba, Ignasi, Martínez-Sáez, Elena, Prudkin, Ludmila, Cuartas, Isabel, Raventós, Carolina, Martínez-Ricarte, Francisco, Poca, M. Antonia, García-Dorado, David, Lahn, Michael M., Yingling, Jonathan M., Rodón, Jordi, Sahuquillo, Juan, Baselga, José, Seoane, Joan
Publikováno v:
In Cancer Cell 2010 18(6):655-668
Autor:
P. Balsas, A. Esteve-Arenys, J. Roldán, L. Jiménez, V. Rodríguez, J. Valero, A. Chamorro-Jorganes, R. De La Bellacasa, J. Teixidó, A. Matas-Céspedes, A. Moros, A. Martínez, E. Campo, A. Sáez-Borderías, J. Borrell, P. Pérez-Galán, D. Colomer, G. Roué
Figure S1. IQS019 tyrosine kinase inhibitory profiling. Tyrosine kinase (TK) and tyrosine kinase-like (TKL) kinome tree was elaborated on the basis of residual in vitro kinase activity upon exposure to 100 nM or 1 μM IQS019, by means of Kinome Rende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2945cf6c687f46cc0bce4ed1cbc33563
Autor:
Jordi Rodon, Francisco Martínez-Ricarte, Juan Sahuquillo, Rosa M. Prieto-Sánchez, Laura Rodon, Elena Martínez-Sáez, Gerard Folch, Jonathan M. Yingling, Alba Gonzalez-Junca, Isabel Cuartas, Andrea Sáez-Borderías, M. Antonia Poca, C. Raventós, Michael Lahn, David Garcia-Dorado, Judit Anido, Ignasi Barba, Maria Ángeles Carmona, Ludmila Prudkin, José Baselga, Joan Seoane
Publikováno v:
Cancer Cell. 18:655-668
SummaryGlioma-initiating cells (GICs), also called glioma stem cells, are responsible for tumor initiation, relapse, and therapeutic resistance. Here, we show that TGF-β inhibitors, currently under clinical development, target the GIC compartment in
Autor:
Jose E Martínez-Rodríguez, Andrea Sáez-Borderías, Elvira Munteis, Jaume Roquer, Neus Romo, Miguel López-Botet
Publikováno v:
Clinical Immunology. 137:41-50
NK cell receptors (NKR) are expressed in subsets of NK and CD8+ T cells, lymphocytes involved in multiple sclerosis (MS) pathogenesis. Clinical implications of NKR expression in MS are unknown. Here, we show that the proportions of CD8+ T cells displ
Autor:
Monica Guma, Giuliana Magri, Neus Romo, Andrea Sáez-Borderías, Miguel López-Botet, Ana Angulo
Publikováno v:
ResearcherID
Scopus-Elsevier
Scopus-Elsevier
The inhibitory CD94/NKG2A and activating CD94/NKG2C killer lectin-like receptors specific for HLA-E have been reported to be selectively expressed by discrete NK and T cell subsets. In the present study, minor proportions of NK and T cells coexpressi
Autor:
Andrea Sáez-Borderías, Daniela Pende, Monica Guma, Beatriz Bellosillo, Ana Angulo, Miguel López-Botet
Publikováno v:
European Journal of Immunology. 36:3198-3206
The human NKG2D killer lectin-like receptor (KLR) is coupled by the DAP10 adapter to phosphoinositide 3-kinase (PI3 K) and specifically interacts with different stress-inducible molecules (i.e. MICA, MICB, ULBP) displayed by some tumour and virus-inf
Akademický článek
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Autor:
Francisco Ruiz-Cabello, Neus Romo, Anton W. Langerak, Dennis Tielemans, Miguel López-Botet, Andrea Sáez-Borderías, Julia Cantón
Publikováno v:
Human Immunology, 72(3), 226-228. Elsevier Inc.
A high frequency of CD4(+) T-cell large granular lymphocyte (T-LGL) lymphocytosis occurs in human leukocyte antigen (HLA) -DRB1*0701 individuals displaying monoclonal expansions of V beta 13.1+ CD4(+) T-cell clones, which specifically respond to huma