Cholesin receptor signalling is active in cardiovascular system-associated adipose tissue and correlates with SGLT2i treatment in patients with diabetes

Autor: Aleksandra Ryk, Anna Marcinkiewicz, Jędrzej Chrzanowski, Arkadiusz Mariusz Michalak, Izabela Dróżdz, Jacek Burzyński, Michał Krejca, Wojciech Fendler

Publikováno v: Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-9 (2024)

Abstract Background Recently deorphanized G protein-coupled receptor 146 (GPR146) was shown to respond to signal from a newly identified hormone—cholesin—and to play a role in hepatic lipid metabolism. However, the importance of its biological ac

Externí odkaz: https://doaj.org/article/52c70294f68749b6866fb6b8cab1aa43

Cholesin receptor signalling is active in cardiovascular system-associated adipose tissue and correlates with SGLT2i treatment in patients with diabetes.

Autor: Ryk, Aleksandra¹ (AUTHOR), Marcinkiewicz, Anna² (AUTHOR), Chrzanowski, Jędrzej¹ (AUTHOR), Michalak, Arkadiusz Mariusz^1,3 (AUTHOR), Dróżdz, Izabela⁴ (AUTHOR), Burzyński, Jacek¹ (AUTHOR), Krejca, Michał² (AUTHOR), Fendler, Wojciech¹ (AUTHOR) wojciech.fendler@umed.lodz.pl

Publikováno v: Cardiovascular Diabetology. 6/20/2024, Vol. 23 Issue 1, p1-9. 9p.

Murine alveolar macrophages rapidly accumulate intranasally administered SARS-CoV-2 Spike protein leading to neutrophil recruitment and damage

Autor: Chung Park, Il-Young Hwang, Serena Li-Sue Yan, Sinmanus Vimonpatranon, Danlan Wei, Don Van Ryk, Alexandre Girard, Claudia Cicala, James Arthos, John H Kehrl

Publikováno v: eLife, Vol 12 (2024)

The trimeric SARS-CoV-2 Spike protein mediates viral attachment facilitating cell entry. Most COVID-19 vaccines direct mammalian cells to express the Spike protein or deliver it directly via inoculation to engender a protective immune response. The t

Externí odkaz: https://doaj.org/article/253ce2a9a2df464f99f6267ec26b993b

The V2 domain of HIV gp120 mimics an interaction between CD4 and integrin ⍺4β7.

Autor: Van Ryk, Donald¹ (AUTHOR), Vimonpatranon, Sinmanus^1,2 (AUTHOR), Hiatt, Joe¹ (AUTHOR), Ganesan, Sundar³ (AUTHOR), Chen, Nathalie¹ (AUTHOR), McMurry, Jordan¹ (AUTHOR), Garba, Saadiq¹ (AUTHOR), Min, Susie¹ (AUTHOR), Goes, Livia R.^1,4 (AUTHOR), Girard, Alexandre¹ (AUTHOR), Yolitz, Jason¹ (AUTHOR), Licavoli, Isabella¹ (AUTHOR), Wei, Danlan¹ (AUTHOR), Huang, Dawei⁵ (AUTHOR), Soares, Marcelo A.^4,6 (AUTHOR), Martinelli, Elena⁷ (AUTHOR), Cicala, Claudia¹ (AUTHOR), Arthos, James¹ (AUTHOR) jarthos@niaid.nih.gov

Publikováno v: PLoS Pathogens. 12/8/2023, Vol. 19 Issue 12, p1-26. 26p.

Genotypic structure of micropopulations of domestic pigs at the locus of the ryanodine RYR1 receptor

Autor: T. M. Ryk

Publikováno v: Біологія тварин, Vol 24, Iss 1, Pp 40-43 (2022)

An important problem in transplant medicine is the lack of organs and tissues for human transplantation. One of the promising areas of its solution today is the use of organs and tissues of animals — xenotransplantation. Pigs for medical and biolog

Externí odkaz: https://doaj.org/article/6d7bfdea054f45eea2f076d33521b8d1