Zobrazeno 1 - 10
of 35
pro vyhledávání: '"A. Ruzindana-Umunyana"'
Publikováno v:
In Virology 25 April 2000 270(1):173-179
Publikováno v:
In Virology 1 March 2000 268(1):141-146
Publikováno v:
Virology. 270:173-179
Adenoviruses encode a cysteine protease, adenain, required for uncoating and virion maturation. Adenain activity is regulated by an 11-amino-acid peptide cofactor thiol-bonded distal to the active site. Structural and experimental data suggest that t
Publikováno v:
Virology. 268:141-146
The serpins SCCA1 and SCCA2 are highly expressed in the epithelium of the conducting airways, a common site of infection by group C adenoviruses, such as human adenovirus type 2 (Ad2). Based on the common location we examined a possible interaction b
Publikováno v:
Antiviral Research. 40:45-51
Adenoviruses encode a cysteine protease (AVP) which carries out highly specific cleavages on at least seven viral proteins and two cellular proteins. Virus infectivity is dependent on this function. The three-dimensional positions of the amino acids
Publikováno v:
Antiviral research. 58(2)
Green tea catechins have been reported to inhibit proteases involved in cancer metastasis and infection by influenza virus and HIV. To date there are no effective anti-adenoviral therapies. Consequently, we studied the effect of green tea catechins,
Publikováno v:
Virus research. 89(1)
The adenovirus protease, adenain is functionally required for virion uncoating and virion maturation and release from the infected cell. In addition to hydrolysis of precursor proteins at specific consensus sites, adenain has also been observed to cl
L'identification d'inhibiteurs sélectifs de l'adenain constituait le but majeur de notre recherche. Quelques inhibiteurs classiques de cystéine protéases tels que l'iodoacétamide, la dithiodipyridine et le parachloromercuribenzoate se sont avér
Externí odkaz:
http://savoirs.usherbrooke.ca/handle/11143/4155
Publikováno v:
(Accès réservé UdeS)Droit de reproduction illimitée uniquement pour la création de matériel didactique..
Thèses (Ph.D.)--Université de Sherbrooke (Canada), 2002.
Titre de l'écran-titre (visionné le 20 juin 2006). Publié aussi en version papier.
Titre de l'écran-titre (visionné le 20 juin 2006). Publié aussi en version papier.
Publikováno v:
Antiviral research. 51(3)
Over 100 serotypes of adenoviruses have been implicated in a variety of human and domesticated animal pathologies and some serotypes are widely used as gene transfer vectors. Aside from the limited use of vaccines for specific serotypes, little effor