Zobrazeno 1 - 10
of 982
pro vyhledávání: '"A. Román González"'
Autor:
El-Hamamsy, Laila, Zapata-Cáceres, María, Martín-Barroso, Estefanía, Mondada, Francesco, Zufferey, Jessica Dehler, Bruno, Barbara, Román-González, Marcos
The introduction of computing education into curricula worldwide requires multi-year assessments to evaluate the long-term impact on learning. However, no single Computational Thinking (CT) assessment spans primary school, and no group of CT assessme
Externí odkaz:
http://arxiv.org/abs/2305.19526
Autor:
Zeliha Yalçin, Shiu Yeung Lam, Marieke H. Peuscher, Jaco van der Torre, Sha Zhu, Prasanna V. Iyengar, Daniel Salas-Lloret, Inge de Krijger, Nathalie Moatti, Ruben van der Lugt, Mattia Falcone, Aurora Cerutti, Onno B. Bleijerveld, Liesbeth Hoekman, Román González-Prieto, Jacqueline J. L. Jacobs
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Maintenance of genome integrity requires tight control of DNA damage response (DDR) signalling and repair, with phosphorylation and ubiquitination representing key elements. How these events are coordinated to achieve productive DNA repair r
Externí odkaz:
https://doaj.org/article/5904fb9cf15e4ea0bcf5f618e256368f
Autor:
Daniel Salas-Lloret, Néstor García-Rodríguez, Emily Soto-Hidalgo, Lourdes González-Vinceiro, Carmen Espejo-Serrano, Lisanne Giebel, María Luisa Mateos-Martín, Arnoud H. de Ru, Peter A. van Veelen, Pablo Huertas, Alfred C. O. Vertegaal, Román González-Prieto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Deficiencies in the BRCA1 tumor suppressor gene are the main cause of hereditary breast and ovarian cancer. BRCA1 is involved in the Homologous Recombination DNA repair pathway and, together with BARD1, forms a heterodimer with ubiquitin E3
Externí odkaz:
https://doaj.org/article/3e5701fc02264129ac1bfa7414d7e198
Autor:
Joana S. Rodrigues, Miguel Chenlo, Susana B. Bravo, Sihara Perez-Romero, Maria Suarez-Fariña, Tomas Sobrino, Rebeca Sanz-Pamplona, Román González-Prieto, Manuel Narciso Blanco Freire, Ruben Nogueiras, Miguel López, Laura Fugazzola, José Manuel Cameselle-Teijeiro, Clara V. Alvarez
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-30 (2024)
Abstract The E3 SUMO ligase PIAS2 is expressed at high levels in differentiated papillary thyroid carcinomas but at low levels in anaplastic thyroid carcinomas (ATC), an undifferentiated cancer with high mortality. We show here that depletion of the
Externí odkaz:
https://doaj.org/article/34a05c85bda54bb8a024af079c17fe5c
Autor:
Gustavo Montes-Montes, Román González-Escobedo, Laila N. Muñoz-Castellanos, Graciela D. Avila-Quezada, Obed Ramírez-Sánchez, Alejandra Borrego-Loya, Ismael Ortiz-Aguirre, Zilia Y. Muñoz-Ramírez
Publikováno v:
Nitrogen, Vol 5, Iss 2, Pp 301-314 (2024)
The rhizospheric microorganisms of agricultural crops play a crucial role in plant growth and nutrient cycling. In this study, we isolated two Streptomyces strains, Streptomyces sp. LM32 and Streptomyces sp. LM65, from the rhizosphere of Vitis vinife
Externí odkaz:
https://doaj.org/article/2826bfc7f464460dba6d52dd5163bac4
Publikováno v:
International Journal of Educational Technology in Higher Education, Vol 21, Iss 1, Pp 1-29 (2024)
Abstract In recent years, higher education (HE) globally has witnessed extensive adoption of technology, particularly in teaching and research. The emergence of generative Artificial Intelligence (GenAI) further accelerates this trend. However, the i
Externí odkaz:
https://doaj.org/article/c5c641df05f340258a69dd7400b6cea3
Autor:
Melissa Fernanda Lara Viáfara, Kenyi Kuratomi Nakamura, María Antonia Escobar Mera, Alin Abreu Lomba, Alejandro Román González
Publikováno v:
Repertorio de Medicina y Cirugía, Vol 33, Iss 2 (2024)
Introducción: parte esencial del manejo y control de la pandemia por SARS-CoV-2 ha sido la vacunación. Sin embargo, las sales de aluminio usadas en las vacunas para potenciar el sistema inmune, pueden asociarse con el síndrome autoinmune/autoinfla
Externí odkaz:
https://doaj.org/article/543d03cb928f49e0aa17d438c9f929f1
Autor:
Karen Lorena Palacios Bayona, Pablo Alberto Ceballos Castaño, Lina Marcela Restrepo Giraldo, Carlos Esteban Builes Montaño, Alex Ramirez Rincón, Henry Tovar Cortes, Katherine Restrepo Erazo, Ariana Margarita Sierra Osorio, Sonia Esperanza Gómez Benjumea, Lina Patricia Pradilla Suarez, Doly Nubia Pantoja Guerrero, Alejandro Román González, Hernando Vargas Uricoechea, Carlos Alfonso Builes Barrera, José Alfonso Mora Morantes, Juan Bernardo Pinzón Barco, Alejandro Marín Sánchez
Publikováno v:
Revista Colombiana de Endocrinología, Diabetes y Metabolismo, Vol 11, Iss 2 (2024)
Contexto: en el año 2022 la Asociación Colombiana de Endocrinología, Diabetes y Metabolismo (ACE) se une a la iniciativa Decisiones Acertadas para evitar prácticas médicas excesivas. Objetivo: generar cinco recomendaciones basadas en evidencia
Externí odkaz:
https://doaj.org/article/7f957041e93641c3965463d42dc88d0e
Autor:
Aurora Yáñez-Vilches, Antonia M Romero, Marta Barrientos-Moreno, Esther Cruz, Román González-Prieto, Sushma Sharma, Alfred C O Vertegaal, Félix Prado
Publikováno v:
PLoS Genetics, Vol 20, Iss 5, p e1011148 (2024)
The helicase MCM and the ribonucleotide reductase RNR are the complexes that provide the substrates (ssDNA templates and dNTPs, respectively) for DNA replication. Here, we demonstrate that MCM interacts physically with RNR and some of its regulators,
Externí odkaz:
https://doaj.org/article/74239cd0f5c94000982e420d48db6720
Autor:
Dennys Alexandra Hernández-Torres, Myrna Elizabeth López-Hernández, Maria Elena Camacho-Moll, Mario Bermúdez de León, Katia Peñuelas-Urquides, Laura Adiene González-Escalante, Román González-Reyna, Darinka Laillete García-Leija, Brenda Leticia Escobedo-Guajardo
Publikováno v:
Nutrients, Vol 16, Iss 16, p 2662 (2024)
Aging is commonly accompanied by increased cardiovascular risk and diet plays a crucial role in health condition. The aim of this study was to determine cardiovascular risk factors as predictors of nutritional risk in Mexican older adults. A cross-se
Externí odkaz:
https://doaj.org/article/f6802f86adad4bc5a9b68f612f525052