Zobrazeno 1 - 10
of 27
pro vyhledávání: '"A. Robert Jeffcoat"'
Publikováno v:
Journal of toxicology and environmental health. Part A. 84(15)
The broad spectrum antimicrobial/antifungal zinc pyrithione (ZnPT) is used in products ranging from antifouling paint to antidandruff shampoo. The hazard profile of ZnPT was established based upon comprehensive toxicological testing, and products con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f49903ad84d01a49d30e75d88530e6c
https://pubmed.ncbi.nlm.nih.gov/33886436
https://pubmed.ncbi.nlm.nih.gov/33886436
The broad-spectrum antimicrobial zinc pyrithione (ZnPT) is used in numerous products ranging from in-can preservative/mildicide in paints to antidandruff shampoo. Although products containing ZnPT have a long history of safe use, regulatory agencies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25065f0abe72c53ce9d7f8d27e8b9cfd
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 50:171-175
This report describes the preparation of carbon-14 labeled dibutyltin dichloride from carbon-14 labeled barium carbonate in 30% overall radiochemical yield. The key steps were (a) the preparation of carbon-14 labeled butyl bromide from carbon-14 labe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1b9ff36a54276db9a17084cfbdaaf22
https://doi.org/10.1002/jlcr.1219
https://doi.org/10.1002/jlcr.1219
Autor:
James A. Crowell, Marjorie G Busby, A. Robert Jeffcoat, Brian F. Thomas, Tracy M. Black, Craig P. Albright, Wlodek Lopaczynski, Michael J. Schell, LeAnne T Bloedon, Steven H. Zeisel, Kelly J. Dix
Publikováno v:
The American Journal of Clinical Nutrition. 76:1126-1137
Background: Soy isoflavones are being evaluated as chemopreventive agents for breast and other cancers. Objective: The objective was to perform safety and pharmacokinetic studies of purified unconjugated isoflavone preparations containing genistein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc171c7ecade8f9531cdab7c1488540
https://doi.org/10.1093/ajcn/76.5.1126
https://doi.org/10.1093/ajcn/76.5.1126
Autor:
Kelly J. Dix, Matthew A. Koch, Judith Hill, James A. Crowell, Tracy M. Black, LeAnne T Bloedon, Brian F. Thomas, William D. Heizer, Steven H. Zeisel, Marjorie G Busby, A. Robert Jeffcoat
Publikováno v:
The American Journal of Clinical Nutrition. 75:126-136
Background: Soy isoflavones are potential cancer chemoprevention treatments. Objective: We conducted safety studies of purified unconjugated genistein, daidzein, and glycitein, and defined pharmacokinetic parameters for their absorption and metabolis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fadf8ae997a4435b904a480a3eeeee7
https://doi.org/10.1093/ajcn/75.1.126
https://doi.org/10.1093/ajcn/75.1.126
Autor:
Leanne T Bloeden, Nicole M. Scheffler, Rene’ A Mitchell, A. Robert Jeffcoat, Kelly J. Dix, Sherri S. Brown, Marjory G Busby, Judith Hill, Steven H. Zeisel, Brian F. Thomas
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 760:191-205
Soy isoflavones are becoming of increasing interest as nutritional agents which can be used to combat osteoporosis and hyperlipidemia, and are also being considered as potential cancer chemopreventive compounds. However, prior to their formulation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726d9acf4b17c32e5321aaca62488b1d
https://doi.org/10.1016/s0378-4347(01)00269-9
https://doi.org/10.1016/s0378-4347(01)00269-9
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 41(11)
N,N-dimethylacetoacetamide (DMAAm) is a β-dicarbonyl compound used as an industrial intermediate. This study investigated the disposition and metabolism of [¹⁴C]DMAAm in male rats and female mice. A single oral dose of [¹⁴C]DMAAm (target dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0447fab377d959c5c7edc7bbf14c6228
https://pubmed.ncbi.nlm.nih.gov/21819270
https://pubmed.ncbi.nlm.nih.gov/21819270
Autor:
Leslie M. Fischer, Steven H. Zeisel, James A. Crowell, John L. Valentine, Thomas E Stinchcombe, Matthew A. Koch, Jarol Boan, A. Robert Jeffcoat, Brian F. Thomas, Chrysa Mahoney
Publikováno v:
Nutrition and cancer. 48(2)
A phase I clinical trial was conducted to determine the safety, pharmacokinetic parameters, and efficacy of orally administered isoflavones (genistein and daidzein, potential cancer chemotherapeutic agents) over a 3-mo period in men with prostate neo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c622c6308c47a2b7e43229be5c8a43c5
https://pubmed.ncbi.nlm.nih.gov/15231450
https://pubmed.ncbi.nlm.nih.gov/15231450
Autor:
S McDonald, Robert E. Hicks, C. Edgar Cook, W. Reid White, Mario Perez-Reyez, A. Robert Jeffcoat
Publikováno v:
Pharmacology, biochemistry, and behavior. 40(3)
Six healthy male, paid volunteers smoked one NIDA cigarette containing 1.0% THC each day for 13 consecutive days. They were tested before and after the period of drug administration by the following procedure: the subjects smoked one NIDA marijuana c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a206a397c5e19e0242384531d9cf29
https://pubmed.ncbi.nlm.nih.gov/1666929
https://pubmed.ncbi.nlm.nih.gov/1666929
Autor:
Edgar Cook, C, Brine, Dolores R, Robert Jeffcoat, A, Hill, Judith M, Wall, Monroe E, Perez-Reyes, Mario, Di Guiseppi, Stephanie R
Publikováno v:
Clinical Pharmacology & Therapeutics; May1982, Vol. 31 Issue 5, p625-634, 10p