Zobrazeno 1 - 10
of 2 909
pro vyhledávání: '"A. Rissman"'
Autor:
Yi Sak Kim, Soo-Ho Choi, Keun-Young Kim, Juliana M. Navia-Pelaez, Guy A. Perkins, Seunghwan Choi, Jungsu Kim, Nicolaus Nazarenkov, Robert A. Rissman, Won-Kyu Ju, Mark H. Ellisman, Yury I. Miller
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Microglia-driven neuroinflammation plays an important role in the development of Alzheimer’s disease. Microglia activation is accompanied by the formation and chronic expression of TLR4 inflammarafts, defined as enlarged and cholesterol-ri
Externí odkaz:
https://doaj.org/article/b236636feb864e9f824fbd2a8c8f706a
Autor:
Shahzad Ahmad, Mohammad Aslam Imtiaz, Aniket Mishra, Ruiqi Wang, Marisol Herrera-Rivero, Joshua C. Bis, Myriam Fornage, Gennady Roshchupkin, Edith Hofer, Mark Logue, W. T. Longstreth, Rui Xia, Vincent Bouteloup, Thomas Mosley, Lenore J. Launer, Michael Khalil, Jens Kuhle, Robert A. Rissman, Genevieve Chene, Carole Dufouil, Luc Djoussé, Michael J. Lyons, Kenneth J. Mukamal, William S. Kremen, Carol E. Franz, Reinhold Schmidt, Stephanie Debette, Monique M. B. Breteler, Klaus Berger, Qiong Yang, Sudha Seshadri, N. Ahmad Aziz, Mohsen Ghanbari, M. Arfan Ikram
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Neurofilament light chain (NfL) levels in circulation have been established as a sensitive biomarker of neuro-axonal damage across a range of neurodegenerative disorders. Elucidation of the genetic architecture of blood NfL levels could prov
Externí odkaz:
https://doaj.org/article/14e2c47872a446f281d0e204198d3b52
Autor:
Douglas Galasko, Martin R. Farlow, Brendan P. Lucey, Lawrence S. Honig, Donald Elbert, Randall Bateman, Jeremiah Momper, Ronald G. Thomas, Robert A. Rissman, Judy Pa, Vahan Aslanyan, Archana Balasubramanian, Tim West, Maria Maccecchini, Howard H. Feldman
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Amyloid beta protein (Aβ) is a treatment target in Alzheimer’s Disease (AD). Lowering production of its parent protein, APP, has benefits in preclinical models. Posiphen, an orally administered small molecule, binds to an iron-
Externí odkaz:
https://doaj.org/article/e42d62be4d5d45feab248f4b5d8078a5
Publikováno v:
Communications Psychology, Vol 2, Iss 1, Pp 1-18 (2024)
Abstract Surging interest in individual differences has faced setbacks in light of recent replication crises in psychology, for example in brain-wide association studies exploring brain-behavior correlations. A crucial component of replicability for
Externí odkaz:
https://doaj.org/article/6113ecd548b34bd699192f522c40c4ad
Autor:
Hsin-Pei Wang, Rebeca Scalco, Naomi Saito, Laurel Beckett, My-Le Nguyen, Emily Z. Huie, Lawrence S. Honig, Charles DeCarli, Robert A. Rissman, Andrew F. Teich, Dan M. Mungas, Lee-Way Jin, Brittany N. Dugger
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-12 (2024)
Abstract Cerebrovascular and α-synuclein pathologies are frequently observed alongside Alzheimer disease (AD). The heterogeneity of AD necessitates comprehensive approaches to postmortem studies, including the representation of historically underrep
Externí odkaz:
https://doaj.org/article/2ccca9693bd8481a91ee168a49211a38
Autor:
Rongxiang Tang, Erik Buchholz, Anders M. Dale, Robert A. Rissman, Christine Fennema-Notestine, Nathan A. Gillespie, Donald J Hagler, Michael J. Lyons, Michael C. Neale, Matthew S. Panizzon, Olivia K. Puckett, Chandra A. Reynolds, Carol E. Franz, William S. Kremen, Jeremy A. Elman
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Plasma neurofilament light chain (NfL) is a promising biomarker of neurodegeneration with potential clinical utility in monitoring the progression of neurodegenerative diseases. However, the cross-sectional associations of plasma
Externí odkaz:
https://doaj.org/article/76973dd443624b90a1ebf2477b1724ec
Autor:
Michiyo Iba, Somin Kwon, Changyoun Kim, Marcell Szabo, Liam Horan-Portelance, Maria Lopez-Ocasio, Pradeep Dagur, Cassia Overk, Robert A. Rissman, Eliezer Masliah
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract The neuroinflammatory process in synucleinopathies of the aging population such as Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) involves microglial activation as well as infiltration of the CNS by T cells and natural killer
Externí odkaz:
https://doaj.org/article/c8ac0709bc0142fc94ad06c7597d1500
Autor:
Iba, Michiyo, Lee, Yeon-Joo, Horan-Portelance, Liam, Chang, Katherine, Szabo, Marcell, Rissman, Robert A., You, Sungyong, Masliah, Eliezer, Kim, Changyoun
Publikováno v:
In Brain Behavior and Immunity January 2025 123:254-269
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 2, Pp n/a-n/a (2024)
Abstract Down syndrome (DS) is caused by a third copy of chromosome 21. Alzheimer's disease (AD) is a neurodegenerative condition characterized by the deposition of amyloid‐beta (Aβ) plaques and neurofibrillary tangles in the brain. Both disorders
Externí odkaz:
https://doaj.org/article/e2979a9115524f1284113504fb8de4e0
Autor:
Catherine R. Walsh, Jesse Rissman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract While semantic and episodic memory have been shown to influence each other, uncertainty remains as to how this interplay occurs. We introduce a behavioral representational similarity analysis approach to assess whether semantic space can be
Externí odkaz:
https://doaj.org/article/938409f93b4a460f8760b9f7db093bf8