Indigenous frameworks for data-intensive humanities: recalibrating the past through knowledge engineering and generative modelling.

Autor: Sydney Shep, Marcus Frean, Rhys Owen, Rere-No-A-Rangi Pope, Pikihuia Reihana, Valerie Chan

Publikováno v: Journal of Data Mining and Digital Humanities, Vol HistoInformatics, Iss HistoInformatics (2021)

Identifying, contacting and engaging missing shareholders constitutes an enormous challenge for Māori incorporations, iwi and hapū across Aotearoa New Zealand. Without accurate data or tools to har-monise existing fragmented or conflicting data sou

Externí odkaz: https://doaj.org/article/0504d86854b64d06acff05dbf521eb41

Oxidative Stress From DGAT1 Oncoprotein Inhibition Suppresses Tumor Growth When ROS Defenses Are Also Breached

Autor: Daniel Wilcock, Andrew Badrock, Chun Wai Wong, Rhys Owen, Melissa Guerin, Andrew Southam, Hannah Johnston, Brian Telfer, Paul Fullwood, Joanne Watson, Harriet Ferguson, Jennifer Ferguson, Gavin R. Lloyd, Andris Jankevics, Warwick B. Dunn, Claudia Wellbrock, Paul Lorigan, Craig Ceol, Chiara Francavilla, Michael P. Smith, Adam Hurlstone

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1cb9b61454fb427428fcb6c242024432
https://doi.org/10.2139/ssrn.3933295

DGAT1 is a lipid metabolism oncoprotein that enables cancer cells to accumulate fatty acid while avoiding lipotoxicity

Autor: Daniel J. Wilcock, Andrew P. Badrock, Rhys Owen, Melissa Guerin, Andrew D. Southam, Hannah Johnston, Samuel Ogden, Paul Fullwood, Joanne Watson, Harriet Ferguson, Jennifer Ferguson, Daniel A. Richardson, Gavin R. Lloyd, Andris Jankevics, Warwick B. Dunn, Claudia Wellbrock, Paul Lorigan, Craig Ceol, Chiara Francavilla, Michael P. Smith, Adam F. L. Hurlstone

Dysregulated cellular metabolism is a hallmark of cancer. As yet, few druggable oncoproteins directly responsible for this hallmark have been identified. Increased fatty acid acquisition allows cancer cells to meet their membrane biogenesis, ATP, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3fe01a3cb763345ac74960293b467e5a
https://doi.org/10.1101/2020.06.23.166603

Epithelial Microvesicles Promote an Inflammatory Phenotype in Fibroblasts

Autor: Gethin Rhys Owen, P. Huang, Liangjia Bi, Ya Shen, Jyrki Heino, Jiarui Bi, Leeni Koivisto, Anne Rokka, Zhejun Wang, Markus Haapasalo, Hannu Larjava, Lari Häkkinen

Publikováno v: Journal of Dental Research. 95:680-688

Microvesicles (MVs) are extracellular vesicles secreted by various cell types that are involved in intercellular communication. We hypothesized that in human periodontal disease, the pocket epithelium releases MVs, which then modulate gene expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49a56ccc0789471c1db2000ac8fddc2
https://doi.org/10.1177/0022034516633172

Reduced soil respiration beneath invasive Rhododendron ponticum persists after cutting and is related to substrate quality rather than microbial community

Autor: David W. Johnson, John Scullion, Rhys Owen, Dylan Gwynn-Jones, Gordon G. Allison, Gruffydd Lloyd Jones, Heather Stott, Geraint Trefor Williams

Publikováno v: Jones, G, Scullion, J, Allison, G, Stott, H, Johnson, D, Owen, R, Williams, G & Gwynn-Jones, D 2019, ' Reduced soil respiration beneath invasive Rhododendron ponticum persists after cutting and is related to substrate quality rather than microbial community ', Soil Biology & Biochemistry, vol. 138, pp. 107577 . https://doi.org/10.1016/j.soilbio.2019.107577

Invasive plants depositing recalcitrant, polyphenol-rich leaf litter may alter decomposition dynamics, leading to an accumulation of soil organic matter. Removing invasives is critical in restoring native habitats, but our understanding of its impact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a468842df10e92bdc59a0780e3af19
https://doi.org/10.1016/j.soilbio.2019.107577