Zobrazeno 1 - 10
of 157
pro vyhledávání: '"A. Rapchak"'
Publikováno v:
PLoS Pathogens, Vol 18, Iss 12, p e1011039 (2022)
Merkel cell polyomavirus (MCV) is a small DNA tumor virus that persists in human skin and causes Merkel cell carcinoma (MCC) in immunocompromised individuals. The multi-functional protein MCV small T (sT) activates viral DNA replication by stabilizin
Externí odkaz:
https://doaj.org/article/a9389a48e04e47448f4e50a5c2802d95
Autor:
Thong T. Luong, Zheqi Li, Nolan Priedigkeit, Phoebe S. Parker, Stefanie Böhm, Kyle Rapchak, Adrian V. Lee, Kara A. Bernstein
Publikováno v:
PLoS Genetics, Vol 18, Iss 9 (2022)
Human RECQL4 is a member of the RecQ family of DNA helicases and functions during DNA replication and repair. RECQL4 mutations are associated with developmental defects and cancer. Although RECQL4 mutations lead to disease, RECQL4 overexpression is a
Externí odkaz:
https://doaj.org/article/b0869b1cbb9f4c4e8c2c9dbdee82b685
Autor:
Robert H. Dolin, Shaileshbhai R. Gothi, Aziz Boxwala, Bret S. E. Heale, Ammar Husami, James Jones, Himanshu Khangar, Shubham Londhe, Frank Naeymi-Rad, Soujanya Rao, Barbara Rapchak, James Shalaby, Varun Suraj, Ning Xie, Srikar Chamala, Gil Alterovitz
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background VCF formatted files are the lingua franca of next-generation sequencing, whereas HL7 FHIR is emerging as a standard language for electronic health record interoperability. A growing number of FHIR-based clinical genomics applicati
Externí odkaz:
https://doaj.org/article/99d9ca08a72249798090ee08fc5ab9d3
Autor:
Braulio Bonilla, Alexander J Brown, Sarah R Hengel, Kyle S Rapchak, Debra Mitchell, Catherine A Pressimone, Adeola A Fagunloye, Thong T Luong, Reagan A Russell, Rudri K Vyas, Tony M Mertz, Hani S Zaher, Nima Mosammaparast, Ewa P Malc, Piotr A Mieczkowski, Steven A Roberts, Kara A Bernstein
Publikováno v:
eLife, Vol 10 (2021)
Three-methyl cytosine (3meC) are toxic DNA lesions, blocking base pairing. Bacteria and humans express members of the AlkB enzymes family, which directly remove 3meC. However, other organisms, including budding yeast, lack this class of enzymes. It r
Externí odkaz:
https://doaj.org/article/3c12084a8dba4d91b827c88a4ddb1f77
Autor:
Rapchak, Kyle1 (AUTHOR), Yagobian, Shiva D.1 (AUTHOR), Moore, Jackson1 (AUTHOR), Khattri, Michelle1 (AUTHOR), Shuda, Masahiro1,2 (AUTHOR) mas253@pitt.edu
Publikováno v:
PLoS Pathogens. 12/27/2022, Vol. 18 Issue 12, p1-36. 36p.
Autor:
Marcia Rapchak
Publikováno v:
Communications in Information Literacy, Vol 15, Iss 1 (2021)
Critical librarianship, which critiques the role of libraries and information professionals in maintaining systems of oppression, has been growing in popularity in the profession, and instructors in Library and Information Science (LIS) have begun to
Externí odkaz:
https://doaj.org/article/0e7ecc812dfd4ab69711a28aa89ef244
Autor:
Rapchak, Marcia E.
Publikováno v:
In The Journal of Academic Librarianship May 2018 44(3):383-390
Publikováno v:
Journal of Education for Library and Information Science. 64:89-98
This paper explores the practice of ungrading, a movement embraced by a growing number of teachers and professors who see the process of grading as disconnected and sometimes counter to the learning goals they have for their students. We discuss the
Publikováno v:
In Radiotherapy and Oncology May 2024 194 Supplement 1:S2088-S2090
Autor:
Bizunesh Abere, Hongzhao Zhou, Masahiro Shuda, Donna B. Stolz, Kyle Rapchak, Patrick S. Moore, Yuan Chang
Publikováno v:
Viruses, Vol 14, Iss 3, p 473 (2022)
Merkel cell polyomavirus (MCV) causes one of the most aggressive human skin cancers, but laboratory studies on MCV replication have proven technically difficult. We report the first recombinase-mediated MCV minicircle (MCVmc) system that generates hi
Externí odkaz:
https://doaj.org/article/b9f4e13cf5f64dde91b5fdb17227ff80