Zobrazeno 1 - 10
of 232
pro vyhledávání: '"A. Randrup Thomsen"'
Autor:
Mark Aninakwah Asante, Martin Ekholm Michelsen, Mithuna Mille Balakumar, Buddheera Kumburegama, Amin Sharifan, Allan Randrup Thomsen, Steven Kwasi Korang, Christian Gluud, Sonia Menon
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background To combat coronavirus disease 2019 (COVID-19), booster vaccination strategies are important. However, the optimal administration of booster vaccine platforms remains unclear. Herein, we aimed to assess the benefits and harms of th
Externí odkaz:
https://doaj.org/article/8d3f2cc28cf14c75ae6d6b1074d63c9e
Autor:
Jinglin Zhou, Ida Uddback, Jacob E. Kohlmeier, Jan Pravsgaard Christensen, Allan Randrup Thomsen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMucosal immunization eliciting local T-cell memory has been suggested for improved protection against respiratory infections caused by viral variants evading pre-existing antibodies. However, it remains unclear whether T-cell targeted vac
Externí odkaz:
https://doaj.org/article/2f6df0d634574b2f8b7ce35430728a82
Autor:
Loulieta Nazerai, Shona Caroline Willis, Patricio Yankilevich, Luca Di Leo, Francesca Maria Bosisio, Alex Frias, Corine Bertolotto, Jacob Nersting, Maria Thastrup, Soren Buus, Allan Randrup Thomsen, Morten Nielsen, Kristoffer Staal Rohrberg, Kjeld Schmiegelow, Daniela De Zio
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTImmune-checkpoint inhibitors (ICI) are highly effective in reinvigorating T cells to attack cancer. Nevertheless, a large subset of patients fails to benefit from ICI, partly due to lack of the cancer neoepitopes necessary to trigger an immun
Externí odkaz:
https://doaj.org/article/4dfe4b677ec94c7b9323ef328b78f448
Autor:
Egle Paskeviciute, Mei Chen, Heping Xu, Bent Honoré, Henrik Vorum, Torben Lykke Sørensen, Jan Pravsgaard Christensen, Allan Randrup Thomsen, Mogens Holst Nissen, Maria Abildgaard Steffensen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
During recent years, evidence has emerged that immune privileged sites such as the CNS and the retina may be more integrated in the systemic response to infection than was previously believed. In line with this, it was recently shown that a systemic
Externí odkaz:
https://doaj.org/article/30457082d32b4a29a6d668c4dc46358f
Autor:
Steven Kwasi Korang, Sophie Juul, Emil Eik Nielsen, Joshua Feinberg, Faiza Siddiqui, Giok Ong, Sarah Klingenberg, Areti Angeliki Veroniki, Fanlong Bu, Lehana Thabane, Allan Randrup Thomsen, Janus C. Jakobsen, Christian Gluud
Publikováno v:
Systematic Reviews, Vol 9, Iss 1, Pp 1-15 (2020)
Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19) which has rapidly spread worldwide. Several human randomized clinical trials assessing potential vaccines are currently underw
Externí odkaz:
https://doaj.org/article/a96776f363974196888e726a61154834
Autor:
Steven Kwasi Korang, Elena von Rohden, Areti Angeliki Veroniki, Giok Ong, Owen Ngalamika, Faiza Siddiqui, Sophie Juul, Emil Eik Nielsen, Joshua Buron Feinberg, Johanne Juul Petersen, Christian Legart, Afoke Kokogho, Mathias Maagaard, Sarah Klingenberg, Lehana Thabane, Ariel Bardach, Agustín Ciapponi, Allan Randrup Thomsen, Janus C. Jakobsen, Christian Gluud
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
Background COVID-19 is rapidly spreading causing extensive burdens across the world. Effective vaccines to prevent COVID-19 are urgently needed. Methods and findings Our objective was to assess the effectiveness and safety of COVID-19 vaccines throug
Externí odkaz:
https://doaj.org/article/d265fdc122694029be5bc7b352f544ea
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Expression of programmed cell death-1 receptor (PD-1) has traditionally been linked to T-cell exhaustion, as signaling via PD-1 dampens the functionality of T-cells upon repetitive antigen exposures during chronic infections. However, resent findings
Externí odkaz:
https://doaj.org/article/75d0925f51da454cbb3d2cad29033de9
Autor:
Anette Stryhn, Michael Kongsgaard, Michael Rasmussen, Mikkel Nors Harndahl, Thomas Østerbye, Maria Rosaria Bassi, Søren Thybo, Mette Gabriel, Morten Bagge Hansen, Morten Nielsen, Jan Pravsgaard Christensen, Allan Randrup Thomsen, Soren Buus
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Examining CD8+ and CD4+ T cell responses after primary Yellow Fever vaccination in a cohort of 210 volunteers, we have identified and tetramer-validated 92 CD8+ and 50 CD4+ T cell epitopes, many inducing strong and prevalent (i.e., immunodominant) T
Externí odkaz:
https://doaj.org/article/b8fb5297c13149d797fdd9685dc406b6
Autor:
Loulieta Nazerai, Amalie Skak Schøller, Maria Rosaria Bassi, Søren Buus, Anette Stryhn, Jan Pravsgaard Christensen, Allan Randrup Thomsen
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Zika virus (ZIKV), a mosquito-borne flavivirus, came into the spotlight in 2016 when it was found to be associated with an increased rate of microcephalic newborns in Brazil. The virus has further been recognized to cause neurologic complications in
Externí odkaz:
https://doaj.org/article/25037e12d8884f6987145d3fded7907e
Publikováno v:
APMIS. 131:37-60
The emergence of SARS-CoV-2 caught the world off guard resulting in a global health crisis. Even though COVID-19 have caused the death of millions of people and many countries are still battling waves of infections, the odds of the pandemic ending so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc6aeb5c9eadbb3bbe2be37f6994b2c
https://doi.org/10.1111/apm.13284
https://doi.org/10.1111/apm.13284