Zobrazeno 1 - 10
of 3 352
pro vyhledávání: '"A. Ragno"'
Publikováno v:
Hydrology and Earth System Sciences, Vol 28, Pp 3919-3930 (2024)
Coastal regions have experienced significant environmental changes and increased vulnerability to floods caused by the combined effect of multiple flood drivers such as storm surge, heavy rainfall and river discharge, i.e., compound floods. Hence, fo
Externí odkaz:
https://doaj.org/article/89b57a5daa2e48478787e3e0237dc9df
Autor:
Gaetano Pezzicoli, Vittoria Musci, Federica Ciciriello, Francesco Salonne, Paola Cafforio, Nicoletta Lionetti, Anna Ragno, Mimma Rizzo
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
While the clear-cell renal cell carcinoma (ccRCC) treatment has undergone several paradigm shifts in recent years, the non-clear cell renal cell carcinoma (nccRCC) therapeutic approach has yet to be extensively investigated and improved. The WHO 2022
Externí odkaz:
https://doaj.org/article/b2cc373371144f2094323039a36b21c1
Autor:
Esposito E, Pozza E, Contado C, Pula W, Bortolini O, Ragno D, Toldo S, Casciano F, Bondi A, Zauli E, Secchiero P, Zauli G, Melloni E
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 3513-3536 (2024)
Elisabetta Esposito,1 Elena Pozza,2 Catia Contado,1 Walter Pula,1 Olga Bortolini,3 Daniele Ragno,1 Sofia Toldo,3 Fabio Casciano,4 Agnese Bondi,1 Enrico Zauli,2 Paola Secchiero,4 Giorgio Zauli,3 Elisabetta Melloni4 1Department of Chemical, Pharmaceuti
Externí odkaz:
https://doaj.org/article/3e165a57e5384a8895f66851c26bf09e
Autor:
Pablo Iruzubieta, César Augusto Pinheiro Ferreira Alves, Aisha M. Al Shamsi, Gehad ElGhazali, Maha S. Zaki, Lorenzo Pinelli, Diego Lopergolo, Bernard P.H. Cho, Amy A. Jolly, Amna Al Futaisi, Fatema Al-Amrani, Jessica Galli, Elisa Fazzi, Katarina Vulin, Francisco Barajas-Olmos, Holger Hengel, Bayan Mohammed Aljamal, Vahideh Nasr, Farhad Assarzadegan, Michele Ragno, Luigi Trojano, Naomi Meave Ojeda, Arman Çakar, Silvia Bianchi, Francesca Pescini, Anna Poggesi, Amal Al Tenalji, Majid Aziz, Rahema Mohammad, Aziza Chedrawi, Nicola De Stefano, Giovanni Zifarelli, Ludger Schöls, Tobias B. Haack, Adriana Rebelo, Stephan Zuchner, Filiz Koc, Lyn R. Griffiths, Lorena Orozco, Karla García Helmes, Meisam Babaei, Peter Bauer, Won Chan Jeong, Ehsan Ghayoor Karimiani, Miriam Schmidts, Joseph G. Gleeson, Wendy K. Chung, Fowzan Sami Alkuraya, Bita Shalbafan, Hugh S. Markus, Henry Houlden, Reza Maroofian
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105297- (2024)
Summary: Background: NOTCH3 encodes a transmembrane receptor critical for vascular smooth muscle cell function. NOTCH3 variants are the leading cause of hereditary cerebral small vessel disease (SVD). While monoallelic cysteine-involving missense var
Externí odkaz:
https://doaj.org/article/dcf457b6550e45488640bb16d06d46d7
Publikováno v:
Geophysical Research Letters, Vol 51, Iss 17, Pp n/a-n/a (2024)
Abstract We investigate whether geomorphic signatures of permafrost are embedded in planforms of river meanders, and we inquire as to how physical factors unique to permafrost environments are able to affect their dynamics. By exploiting satellite im
Externí odkaz:
https://doaj.org/article/a7fdafdf14724ae6b62df13e7a517ceb
Autor:
Diakomopoulos, Faidon, Antonini, Alessandro, Bakker, Alexander Maria Rogier, Stancanelli, Laura Maria, Hrachowitz, Markus, Ragno, Elisa
Publikováno v:
In Coastal Engineering December 2024 194
Since the introduction of artificial intelligence in medicinal chemistry, the necessity has emerged to analyse how molecular property variation is modulated by either single atoms or chemical groups. In this paper, we propose to train graph-to-graph
Externí odkaz:
http://arxiv.org/abs/2202.05704
It is well known that Drug Design is often a costly process both in terms of time and economic effort. While good Quantitative Structure-Activity Relationship models (QSAR) can help predicting molecular properties without the need to synthesize them,
Externí odkaz:
http://arxiv.org/abs/2202.05703
Autor:
Arianna Romani, Giada Lodi, Fabio Casciano, Arianna Gonelli, Paola Secchiero, Giorgio Zauli, Olga Bortolini, Giuseppe Valacchi, Daniele Ragno, Agnese Bondi, Mascia Benedusi, Elisabetta Esposito, Rebecca Voltan
Publikováno v:
Cells, Vol 13, Iss 20, p 1678 (2024)
This study evaluated ethosomes as a novel nanodelivery system for nutlin-3a, a known MDM2 inhibitor and activator of the p53 pathway, to improve nutlin-3a’s poor solubility, limiting its bio-distribution and therapeutic efficacy. The potential of n
Externí odkaz:
https://doaj.org/article/233a07d992ad48b78b2309ec85070564