Identification of kinase inhibitors as potential host-directed therapies for intracellular bacteria

Autor: Robin H. G. A. van den Biggelaar, Kimberley V. Walburg, Susan J. F. van den Eeden, Cassandra L. R. van Doorn, Eugenia Meiler, Alex S. de Ries, M. Chiara Fusco, Annemarie H. Meijer, Tom H. M. Ottenhoff, Anno Saris

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)

Abstract The emergence of antimicrobial resistance has created an urgent need for alternative treatments against bacterial pathogens. Here, we investigated kinase inhibitors as potential host-directed therapies (HDTs) against intracellular bacteria,

Externí odkaz: https://doaj.org/article/6fef437e9d004484ab19c1ec22e82119

Pharmacological Poly (ADP-Ribose) Polymerase Inhibitors Decrease Mycobacterium tuberculosis Survival in Human Macrophages

Autor: Cassandra L. R. van Doorn, Sanne A. M. Steenbergen, Kimberley V. Walburg, Tom H. M. Ottenhoff

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Diabetes mellites (DM) is correlated with increased susceptibility to and disease progression of tuberculosis (TB), and strongly impairs effective global TB control measures. To better control the TB-DM co-epidemic, unravelling the bidirectional inte

Externí odkaz: https://doaj.org/article/fd971f80c2f9413188a89fec032c4eb1

Climate change and health in Southeast Asia – defining research priorities and the role of the Wellcome Trust Africa Asia Programmes

Autor: A Bonell, Iqbal R. F. Elyazar, R van Doorn, Thanh Ngo-Duc, G Thwaites, D H Dang Giang, N T Xuan Chau, Mary Chambers, Arjen M. Dondorp, Louise Thwaites, P Quang Thai, Elizabeth A. Ashley, Damien Keng Yen Ming, Evelyne Kestelyn, H Ngoc Nhung, Sophie Yacoub, N V Vinh Chau, Marc Choisy, Henry Surendra, G N Thi, Angela McBride, M Evans, Rapeephan R. Maude, H Nguyen Quang, Rachel Lowe, H N Dan Thanh, C Ho Quang

Publikováno v: Wellcome Open Research
Wellcome Open Research, 6:278. F1000 Research Ltd.

This article summarises a recent virtual meeting organised by the Oxford University Clinical Research Unit in Vietnam on the topic of climate change and health, bringing local partners, faculty and external collaborators together from across the Well

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0978d0b4df1c8b75198c268ca79e4e10
https://ora.ox.ac.uk/objects/uuid:e3cc9ea9-915f-4068-9f9a-bd87270ce8f6

Neotypification of Fusarium chlamydosporum - a reappraisal of a clinically important species complex

Autor: R. van Doorn, Pedro W. Crous, Lorenzo Lombard

Publikováno v: Fungal Systematics and Evolution
Fungal Systematics and Evolution, 4, 183-200
Fungal Systematics and Evolution, 4(1), 183-200. Westerdijk Fungal Biodiversity Institute
Fungal Systematics and Evolution 4 (2019)

Fusarium chlamydosporum represents a well-defined morpho-species of both phytopathological and clinical importance. Presently, five phylo-species lacking Latin binomials have been resolved in the F. chlamydosporum species complex (FCSC). Naming these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3caf4f989cb47808f5a2fed8f551eb6c
https://hdl.handle.net/20.500.11755/976872d1-70ce-406a-84f7-0e9e7adea13f

Labor Markets and Social Policy in a Rapidly Transforming and Aging Thailand

Autor: M Bandaogo, R Van Doorn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b849de6f192cc623ed9a871b05e503de
https://doi.org/10.1596/37234