Zobrazeno 1 - 10
of 185
pro vyhledávání: '"A. R. Padgett"'
Autor:
Rodrigo Delgadillo, Anthony M. Deana, John C. Ford, Matthew T. Studenski, Kyle R. Padgett, Matthew C. Abramowitz, Alan Dal Pra, Benjamin O. Spieler, Nesrin Dogan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Extracting longitudinal image quantitative data, known as delta-radiomics, has the potential to capture changes in a patient’s anatomy throughout the course of radiation treatment for prostate cancer. Some of the major challenges of delta-
Externí odkaz:
https://doaj.org/article/9acffde88e674e5591b0c0def42a8a89
Autor:
Charlotte L. Ahls, Duncan Emsweller, Seth J. Helfers, Xin Niu, Douglas Wilson, Leah R. Padgett, Paul K. Drain
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Sputum collection and testing for tuberculosis (TB) have been problematic due to the potential for aerosolization, difficulty in generating a quality sample, and complex DNA extraction methods. Tongue swabs are inexpensive, minimally invasiv
Externí odkaz:
https://doaj.org/article/919d7b6d2c8b48dba2c731b4cbddb16c
Autor:
Rodrigo Delgadillo, Benjamin O. Spieler, Anthony M. Deana, John C. Ford, Deukwoo Kwon, Fei Yang, Matthew T. Studenski, Kyle R. Padgett, Matthew C. Abramowitz, Alan Dal Pra, Radka Stoyanova, Nesrin Dogan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract For prostate cancer (PCa) patients treated with definitive radiotherapy (RT), acute and late RT-related genitourinary (GU) toxicities adversely impact disease-specific quality of life. Early warning of potential RT toxicities can prompt inte
Externí odkaz:
https://doaj.org/article/a8e12246329f4b3795929841a3819432
Autor:
Leah R. Padgett, Mollie R. Shinkle, Spencer Rosario, Tracy Murray Stewart, Jackson R. Foley, Robert A. Casero, Jr., Myung Hee Park, Wendy K. Chung, Teresa L. Mastracci
Publikováno v:
HGG Advances, Vol 4, Iss 3, Pp 100206- (2023)
Summary: DHPS deficiency is a rare genetic disease caused by biallelic hypomorphic variants in the Deoxyhypusine synthase (DHPS) gene. The DHPS enzyme functions in mRNA translation by catalyzing the post-translational modification, and therefore acti
Externí odkaz:
https://doaj.org/article/e7637e4d3aca4a68831a2b5aa9c94073
Autor:
Michalina A. Montaño, Meagan J. Bemer, Kate B. Heller, Allison Meisner, Zarna Marfatia, Elena A. Rechkina, Leah R. Padgett, Charlotte L. Ahls, Douglas Rains, Linhui Hao, Tien-Ying Hsiang, Gerard A. Cangelosi, Alexander L. Greninger, Jason L. Cantera, Allison Golden, Roger B. Peck, David S. Boyle, Michael Gale, Jr, Paul K. Drain
Publikováno v:
International Journal of Infectious Diseases, Vol 117, Iss , Pp 287-294 (2022)
Objectives: This study assesses and compares the performance of different swab types and specimen collection sites for SARS-CoV-2 testing, to reference standard real-time reverse transcriptase-polymerase chain reaction (RT-PCR) and viral culture. Met
Externí odkaz:
https://doaj.org/article/eff16240d3474357915a98a71b334683
Autor:
Ryder M. Schmidt, Rodrigo Delgadillo, John C. Ford, Kyle R. Padgett, Matthew Studenski, Matthew C. Abramowitz, Benjamin Spieler, Yihang Xu, Fei Yang, Nesrin Dogan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract This study provides a quantitative assessment of the accuracy of a commercially available deformable image registration (DIR) algorithm to automatically generate prostate contours and additionally investigates the robustness of radiomic feat
Externí odkaz:
https://doaj.org/article/d1799194bbfe4db99c190917f5da1c0a
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009335 (2021)
Toxoplasma gondii is an obligate intracellular parasite that can cause serious opportunistic disease in the immunocompromised or through congenital infection. To progress through its life cycle, Toxoplasma relies on multiple layers of gene regulation
Externí odkaz:
https://doaj.org/article/27befc67810c4456835ec4a6052bc7f2
Autor:
Leah R Padgett, Lauren A Kennington, Charlotte L Ahls, Delini K Samarasinghe, Yuan-Po Tu, Michelle L Wallander, Shawna D Cooper, James S Elliott, Douglas Rains
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0245423 (2021)
BackgroundIn order to identify an inexpensive yet highly stable SARS-CoV-2 collection device as an alternative to foam swabs stored in transport media, both contrived ("surrogate") CoV-positive and patient-collected spun polyester swabs stored in dry
Externí odkaz:
https://doaj.org/article/930e5bb787274f5b985a1e45c269ebd5
Autor:
Brian Hart, Yuan-Po Tu, Rachel Jennings, Prateek Verma, Leah R Padgett, Douglas Rains, Deneen Vojta, Ethan M Berke
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0241100 (2020)
Both polyester and foam nasal swabs were collected from convalescent COVID-19 patients at a single visit and stored in viral transport media (VTM), saline or dry. Sensitivity of each swab material and media combination were estimated, three by three
Externí odkaz:
https://doaj.org/article/8d6054a0c8574a5ab5560f8bf5eff19a
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230627 (2020)
The gene encoding eukaryotic initiation factor 5A (EIF5A) is found in diabetes-susceptibility loci in mouse and human. eIF5A is the only protein known to contain hypusine (hydroxyputrescine lysine), a polyamine-derived amino acid formed post-translat
Externí odkaz:
https://doaj.org/article/17dbb945de5f4967a98abb05dfd36132