Zobrazeno 1 - 10
of 10
pro vyhledávání: '"A. R. Meinicke"'
Autor:
André R. Meinicke, Alicia J. Kowaltowski, Anibal E. Vercesi, Roger F. Castilho, Mercedes T. Grijalba
Publikováno v:
Bioscience Reports. 17:43-52
We have provided evidence that mitochondrial membrane permeability transition induced by inorganic phosphate, uncouplers or prooxidants such as t-butyl hydroperoxide and diamide is caused by a Ca2+-stimulated production of reactive oxygen species (RO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa019e02efc57fde59a290694b55c3ee
https://doi.org/10.1023/a:1027335217774
https://doi.org/10.1023/a:1027335217774
Autor:
Etelvino J. H. Bechara, Ana Maria da Costa Ferreira, André R. Meinicke, Anibal E. Vercesi, Sı́lvio S. Zavan
Publikováno v:
Archives of Biochemistry and Biophysics. 328:239-244
Ruthenium red (RR), an ammoniated form of tris -ruthenium III,IV,III oxychloride, has been widely used in the micromolar range as a strong and specific inhibitor of in vitro and in vivo Ca 2+ -mediated biochemical processes without regard for its red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6710edea0aa312e41eb9c64da467546a
https://doi.org/10.1006/abbi.1996.0169
https://doi.org/10.1006/abbi.1996.0169
Publikováno v:
Molecular and Cellular Biochemistry. 145:53-60
It is well established that several iron complexes can induce oxidative damage in hepatic mitochondrial membranes by catalyzing the formation of OH radicals and/or by promoting lipid peroxidation. This is a relevant process for the molecular basis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b57b58772904705d777688dd0daf1f6
https://doi.org/10.1007/bf00925713
https://doi.org/10.1007/bf00925713
Autor:
Silvia N.J. Moreno, Anibal E. Vercesi, E. C. Fernandes, Roberto Docampo, A. R. Meinicke, C F Bernardes
Publikováno v:
Journal of Biological Chemistry. 268:8564-8568
Thapsigargin, previously reported to release Ca2+ from non-mitochondrial stores of different cell types, as well as nigericin, were found, when used at high concentrations, to release Ca2+ and collapse the membrane potential of Trypanosoma brucei blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3143788e6b5437ef734599e4258c5ef5
https://doi.org/10.1016/s0021-9258(18)52912-4
https://doi.org/10.1016/s0021-9258(18)52912-4
Publikováno v:
European journal of pharmacology. 428(1)
Pyridoxal isonicotinoyl hydrazone (PIH) is able to prevent iron-mediated hydroxyl radical formation by means of iron chelation and inhibition of redox cycling of the metal. In this study, we investigated the effect of PIH on Fe(II)-citrate-mediated l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292e92ea4bd23a7013ebcfbd6e74a42b
https://pubmed.ncbi.nlm.nih.gov/11779035
https://pubmed.ncbi.nlm.nih.gov/11779035
Publikováno v:
Molecular and cellular biochemistry. 196(1-2)
In this report we study the effect of Fe(III) on lipid peroxidation induced by Fe(II)citrate in mitochondrial membranes, as assessed by the production of thiobarbituric acid-reactive substances and antimycin A-insensitive oxygen uptake. The presence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e32dfbbbed4ecf9adf96c5284e5266c
https://pubmed.ncbi.nlm.nih.gov/10448916
https://pubmed.ncbi.nlm.nih.gov/10448916
Publikováno v:
Stress Adaptation, Prophylaxis and Treatment ISBN: 9781461373193
In this report we study the effect of Fe(III) on lipid peroxidation induced by Fe(II)citrate in mitochondrial membranes, as assessed by the production of thiobarbituric acid-reactive substances and antimycin A-insensitive oxygen uptake. The presence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef004ccf62be00600d5318222d5a1604
https://doi.org/10.1007/978-1-4615-5097-6_20
https://doi.org/10.1007/978-1-4615-5097-6_20
Autor:
Anibal E. Vercesi, André R. Meinicke, Shirley Schreier, Roger F. Castilho, Patricm B. Andrade, Mercedes Toledo Grijalba
Publikováno v:
Free radical research. 28(3)
In the present study we show that K+/H+ hydroxyl-containing ionophores lasalocid-A (LAS) and nigericin (NIG) in the nanomolar concentration range, inhibit Fe2+-citrate and 2,2'-azobis(2-amidinopropane) dihydrochloride (ABAP)-induced lipid peroxidatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ff907f388829e2e554825b07a530d3
https://pubmed.ncbi.nlm.nih.gov/9688216
https://pubmed.ncbi.nlm.nih.gov/9688216
Publikováno v:
Archives of biochemistry and biophysics. 349(2)
We have recently shown that ruthenium red, a noncompetitive inhibitor of the mitochondrial Ca 2+ uniporter, can reduce tert -butyl hydroperoxide via a Fenton-type reaction. In respiring mitochondrial preparations containing tert -butyl hydroperoxide,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de40b522ff03ca800649e1be70209a69
https://pubmed.ncbi.nlm.nih.gov/9448715
https://pubmed.ncbi.nlm.nih.gov/9448715
Publikováno v:
The Journal of biological chemistry. 268(12)
Thapsigargin, previously reported to release Ca2+ from non-mitochondrial stores of different cell types, as well as nigericin, were found, when used at high concentrations, to release Ca2+ and collapse the membrane potential of Trypanosoma brucei blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::739e2a16bf92f66f8c53095b87dd0077
https://pubmed.ncbi.nlm.nih.gov/8473301
https://pubmed.ncbi.nlm.nih.gov/8473301