Metastatic breast cancer patient perceptions of somatic tumor genomic testing

Autor: Elizabeth J. Adams, Sarah Asad, Raquel Reinbolt, Katharine A. Collier, Mahmoud Abdel-Rasoul, Susan Gillespie, James L. Chen, Mathew A. Cherian, Anne M. Noonan, Sagar Sardesai, Jeffrey VanDeusen, Robert Wesolowski, Nicole Williams, Charles L. Shapiro, Erin R. Macrae, Robert Pilarski, Amanda E. Toland, Leigha Senter, Bhuvaneswari Ramaswamy, Clara N. Lee, Maryam B. Lustberg, Daniel G. Stover

Publikováno v: BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)

Abstract Background To assess metastatic breast cancer (MBC) patient psychological factors, perceptions, and comprehension of tumor genomic testing. Methods In a prospective, single institution, single-arm trial, patients with MBC underwent next-gene

Externí odkaz: https://doaj.org/article/2f48ce7ba64647fa9b6238930db202e1

Structure of bacterial phospholipid transporter MlaFEDB with substrate bound

Autor: Nicolas Coudray, Georgia L Isom, Mark R MacRae, Mariyah N Saiduddin, Gira Bhabha, Damian C Ekiert

Publikováno v: eLife, Vol 9 (2020)

In double-membraned bacteria, phospholipid transport across the cell envelope is critical to maintain the outer membrane barrier, which plays a key role in virulence and antibiotic resistance. An MCE transport system called Mla has been implicated in

Externí odkaz: https://doaj.org/article/4016616d4aad4d58a6b5047540cc998d

Measurement of the beam-helicity asymmetry in photoproduction of π0η pairs on carbon, aluminum, and lead

Autor: V. Sokhoyan, S. Prakhov, A. Fix, S. Abt, P. Achenbach, P. Adlarson, F. Afzal, P. Aguar-Bartolomé, Z. Ahmed, K. Altangerel, J.R.M. Annand, H.J. Arends, K. Bantawa, M. Bashkanov, R. Beck, M. Biroth, N.S. Borisov, A. Braghieri, W.J. Briscoe, S. Cherepnya, F. Cividini, C. Collicott, S. Costanza, A. Denig, M. Dieterle, E.J. Downie, P. Drexler, M.I. Ferretti Bondy, L.V. Fil'kov, S. Gardner, S. Garni, D.I. Glazier, I. Gorodnov, W. Gradl, M. Günther, G.M. Gurevich, L. Heijkenskjöld, D. Hornidge, G.M. Huber, A. Käser, V.L. Kashevarov, S. Kay, I. Keshelashvili, R. Kondratiev, M. Korolija, B. Krusche, A. Lazarev, K. Livingston, S. Lutterer, I.J.D. MacGregor, R. Macrae, D.M. Manley, P.P. Martel, J.C. McGeorge, D.G. Middleton, R. Miskimen, E. Mornacchi, C. Mullen, A. Mushkarenkov, A. Neganov, A. Neiser, M. Oberle, M. Ostrick, P.B. Otte, D. Paudyal, P. Pedroni, A. Powell, E. Rickert, G. Ron, T. Rostomyan, A. Sarty, C. Sfienti, K. Spieker, O. Steffen, I.I. Strakovsky, B. Strandberg, Th. Strub, I. Supek, A. Thiel, M. Thiel, A. Thomas, M. Unverzagt, Yu.A. Usov, S. Wagner, N.K. Walford, D.P. Watts, D. Werthmüller, J. Wettig, L. Witthauer, M. Wolfes, N. Zachariou

Publikováno v: Physics Letters B, Vol 802, Iss , Pp - (2020)

The beam-helicity asymmetry was measured, for the first time, in photoproduction of π0η pairs on carbon, aluminum, and lead, with the A2 experimental setup at MAMI. The results are compared to an earlier measurement on a free proton and to the corr

Externí odkaz: https://doaj.org/article/4672004e30f143adaaf9b16333941918

'It's like a burden on the head': Redefining adequate menstrual hygiene management throughout women's varied life stages in Odisha, India.

Autor: Elizabeth R MacRae, Thomas Clasen, Munmun Dasmohapatra, Bethany A Caruso

Publikováno v: PLoS ONE, Vol 14, Iss 8, p e0220114 (2019)

There has been growing recognition of menstrual hygiene management (MHM) as a significant public health issue. However, research has predominately focused on the experiences of adolescent girls in school settings. The purpose of this research is to e

Externí odkaz: https://doaj.org/article/f2d847e65c494a84a0ae938f47130ba1

Protein–protein interactions in the Mla lipid transport system probed by computational structure prediction and deep mutational scanning

Autor: Mark R. MacRae, Dhenesh Puvanendran, Max A. B. Haase, Nicolas Coudray, Ljuvica Kolich, Cherry Lam, Minkyung Baek, Gira Bhabha, Damian C. Ekiert

Publikováno v: Journal of Biological Chemistry. 299:104744

The outer membrane (OM) of Gram-negative bacteria is an asymmetric bilayer that protects the cell from various external stressors, such as antibiotics. The Mla transport system is implicated in theMaintenance of outer membraneLipidAsymmetry and is th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d91c7415367e2edb58cdc65f26563d
https://doi.org/10.1016/j.jbc.2023.104744