Zobrazeno 1 - 10
of 256
pro vyhledávání: '"A. R. Klatt"'
Autor:
Christopher M. Basting, Robert Langat, Courtney A. Broedlow, Candace R. Guerrero, Tyler D. Bold, Melisa Bailey, Adrian Velez, Ty Schroeder, Jonah Short-Miller, Ross Cromarty, Zachary J. Mayer, Peter J. Southern, Timothy W. Schacker, Sandra E. Safo, Carolyn T. Bramante, Christopher J. Tignanelli, Luca Schifanella, Nichole R. Klatt
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT Coronavirus disease 2019 (COVID-19) and its associated severity have been linked to uncontrolled inflammation and may be associated with changes in the microbiome of mucosal sites including the gastrointestinal tract and oral cavity. These s
Externí odkaz:
https://doaj.org/article/ecf5458c7c234187a4ce288a70d501e9
Autor:
Cordelia Manickam, Amit A Upadhyay, Griffin Woolley, Kyle W Kroll, Karen Terry, Courtney A Broedlow, Nichole R Klatt, Steven E Bosinger, R Keith Reeves
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1012223 (2024)
Natural killer-like B (NKB) cells are unique innate immune cells expressing both natural killer (NK) and B cell receptors. As first responders to infection, they secrete IL-18 to induce a critical cascade of innate and adaptive immune cell infiltrati
Externí odkaz:
https://doaj.org/article/66bb7e6cf16643e8817768d7427341ee
Autor:
Hoseung Song, Wodan Ling, Ni Zhao, Anna M. Plantinga, Courtney A. Broedlow, Nichole R. Klatt, Tiffany Hensley-McBain, Michael C. Wu
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Microbial communities are known to be closely related to many diseases, such as obesity and HIV, and it is of interest to identify differentially abundant microbial species between two or more environments. Since the abundances or
Externí odkaz:
https://doaj.org/article/7478464c58bc477f98f48d5f4a4f1bfd
Autor:
A. R. Berard, T. Hensley-McBain, L. Noël-Romas, K. Birse, M. Abou, G. Westmacott, S. McCorrister, J. Smedley, Nichole R. Klatt, Adam D. Burgener
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract HIV infection damages the gut mucosa leading to chronic immune activation, increased morbidities and mortality, and antiretroviral therapies, do not completely ameliorate mucosal dysfunction. Understanding early molecular changes in acute in
Externí odkaz:
https://doaj.org/article/7f4851aea4284a95ba95c61d0556002d
Autor:
Katharina S. Woggon, Denise Meinberger, Gabriele Hermes, Annika Roth, Thomas Streichert, Andreas R. Klatt
Publikováno v:
Applied Sciences, Vol 14, Iss 1, p 184 (2023)
C-type lectins (CTLs) are a group of proteins that play a crucial role in immunological functions. With the rise of antibiotic-resistant bacteria, CTLs have emerged as a potential alternative to traditional antibiotics and antimicrobial peptides (AMP
Externí odkaz:
https://doaj.org/article/33aa4d62c60e4b37b1cfb7f5dc296517
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-10 (2022)
Highlights - The COVID-19 pandemic sensitizes medical students to hygienic aspects of venipuncture. - The hygiene compliance of medical students is proportional to the duration of the COVID-19 pandemic. - During the COIVD-19 pandemic, medical student
Externí odkaz:
https://doaj.org/article/1463ff30af374811be85d62c2f0a77bd
Autor:
Matthias Keutmann, Gabriele Hermes, Denise Meinberger, Annika Roth, Jannik Stemler, Oliver A. Cornely, Andreas R. Klatt, Thomas Streichert
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Beneficial effects of vitamin D on COVID-19 progression have been discussed in several studies. Vitamin D stimulates the expression of the antimicrobial peptide LL-37, and evidence shows that LL-37 can antagonize SARS-CoV-2. Therefore, we in
Externí odkaz:
https://doaj.org/article/5291d22e2b45414e8ec88b48dd7156f5
Autor:
Romel D. Mackelprang, Abdelali Filali-Mouhim, Brian Richardson, Francois Lefebvre, Elly Katabira, Allan Ronald, Glenda Gray, Kristen W. Cohen, Nichole R. Klatt, Tiffany Pecor, Connie Celum, M. Juliana McElrath, Sean M. Hughes, Florian Hladik, Mark J. Cameron, Jairam R. Lingappa
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106454- (2023)
Summary: Chronic immune activation during HIV-1 infection contributes to morbidity and mortality in people living with HIV. To elucidate the underlying biological pathways, we evaluated whole blood gene expression trajectories from before, through ac
Externí odkaz:
https://doaj.org/article/14963cece9dd4beca8fe2f3b3e305119
Autor:
Denise Meinberger, Marco G. Drexelius, Joshua Grabeck, Gabriele Hermes, Annika Roth, Dzemal Elezagic, Ines Neundorf, Thomas Streichert, Andreas R. Klatt
Publikováno v:
Antibiotics, Vol 12, Iss 10, p 1532 (2023)
Antimicrobial peptides (AMPs) represent a promising alternative to conventional antibiotics. Sequence changes can significantly improve the therapeutic properties of antimicrobial peptides. In our study, we apply different sequence modifications to e
Externí odkaz:
https://doaj.org/article/443eba95fde3488bb2fa481aff721d14
Autor:
Nandini Avula, Dustin Kakach, Christopher J. Tignanelli, David M. Liebovitz, Jacinda M. Nicklas, Kenneth Cohen, Michael A. Puskarich, Hrishikesh K. Belani, John B. Buse, Nichole R. Klatt, Blake Anderson, Amy B. Karger, Katrina M. Hartman, Barkha Patel, Sarah L. Fenno, Neha V. Reddy, Spencer M. Erickson, David R. Boulware, Thomas A. Murray, Carolyn T. Bramante, COVID-OUT Trial Team
Publikováno v:
Journal of Clinical and Translational Science, Vol 7 (2023)
The COVID-19 pandemic accelerated the development of decentralized clinical trials (DCT). DCT’s are an important and pragmatic method for assessing health outcomes yet comprise only a minority of clinical trials, and few published methodologies exi
Externí odkaz:
https://doaj.org/article/3c0338acdff247859a45e923ea03cc69