Multiple Sklerose und Mikrobiota

Autor: H. Wekerle, R. Hohlfeld

Publikováno v: Der Nervenarzt. 86:925-933

The individual risk of contracting multiple sclerosis (MS) is determined by genetic predisposition as well as environmental factors. In monozygotic twins the concordance rate for MS is approximately 30 % indicating that environmental factors are even

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c136a670a2341e463a013e28a994569
https://doi.org/10.1007/s00115-014-4248-7

Monitoring von Blutparametern unter verlaufsmodifizierender MS-Therapie : Substanzspezifische Relevanz und aktuelle Handlungsempfehlungen

Autor: L, Klotz, A, Berthele, W, Brück, A, Chan, P, Flachenecker, R, Gold, A, Haghikia, K, Hellwig, B, Hemmer, R, Hohlfeld, T, Korn, T, Kümpfel, M, Lang, V, Limmroth, R A, Linker, U, Meier, S G, Meuth, F, Paul, A, Salmen, M, Stangel, B, Tackenberg, H, Tumani, C, Warnke, M S, Weber, T, Ziemssen, F, Zipp, H, Wiendl

Publikováno v: Klotz, L; Berthele, A; Brück, W; Chan, Andrew; Flachenecker, P; Gold, R; Haghikia, A; Hellwig, K; Hemmer, B; Hohlfeld, R; Korn, T; Kümpfel, T; Lang, M; Limmroth, V; Linker, R A; Meier, U; Meuth, S G; Paul, F; Salmen, Anke; Stangel, M; ... (2016). [Monitoring of blood parameters under course-modified MS therapy : Substance-specific relevance and current recommendations for action]. Der Nervenarzt, 87(6), pp. 645-659. Springer 10.1007/s00115-016-0077-1

With the approval of various substances for the immunotherapy of multiple sclerosis (MS), treatment possibilities have improved significantly over the last few years. Indeed, the choice of individually tailored preparations and treatment monitoring f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::45d31251ff42ca58963d60e5031f3d04
https://boris.unibe.ch/87818/1/art%3A10.1007%2Fs00115-016-0077-1.pdf

B- and T-cell responses in multiple sclerosis: Novel approaches offer new insights

Autor: Klaus Dornmair, Edgar Meinl, R. Hohlfeld

Publikováno v: Journal of the Neurological Sciences. 274:5-8

In experimental autoimmune encephalomyelitis (EAE), several target antigens of encephalitogenic T- and B-cell responses have been identified. However, in human multiple sclerosis (MS) the target antigens of pathogenic T and B cells have remained conj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c2d39ab90b8e646c278bcac56f25d3
https://doi.org/10.1016/j.jns.2008.07.006

Autoantigen- und erregerspezifische T- und B-Zellreaktionen bei multipler Sklerose: 'Eine unendliche Geschichte'?

Autor: E. Meinl, G. S. Direskeneli, R. Hohlfeld, T. Derfuß

Publikováno v: Aktuelle Neurologie. 35:345-355

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. In spite of immense efforts in research the cause of the disease is still unknown. It is well accepted that myelin and probably also neurons are damaged by the i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::031a9b8daebddc8d888710612f2b4ad6
https://doi.org/10.1055/s-2008-1067428

Immunpathogenese und Therapie inflammatorischer Myopathien

Autor: R. Hohlfeld, H. Wiendl

Publikováno v: Aktuelle Neurologie. 35:185-191

Inflammatory myopathies are currently subdivided into three main entities: polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM). This categorisation is based on a combination of clinical, histological and immunopathological chara

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7215c1da5144d3b2dde40fd8ecf290be
https://doi.org/10.1055/s-2007-986395