Zobrazeno 1 - 10
of 612
pro vyhledávání: '"A. R. Hayward"'
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 80, Iss 7, Pp 800-805 (2024)
The crystal structures of 4-benzyl-1H-pyrazole (C10H10N2, 1) and 3,5-diamino-4-benzyl-1H-pyrazole (C10H12N4, 2) were measured at 150 K. Although its different conformers and atropenantiomers easily interconvert in solution by annular tautomerism and/
Externí odkaz:
https://doaj.org/article/2cb1c1e18f86477da9bbd2421e1fe8dd
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106624- (2024)
Neuropathic pain is characterised by periodic or continuous hyperalgesia, numbness, or allodynia, and results from insults to the somatosensory nervous system. Peripheral nerve injury induces transcriptional reprogramming in peripheral sensory neuron
Externí odkaz:
https://doaj.org/article/5e69eb9d663c4ed7a877dc8ac323044b
Autor:
Muntsa Rocafort, David B. Gootenberg, Jesús M. Luévano, Jeffrey M. Paer, Matthew R. Hayward, Juliet T. Bramante, Musie S. Ghebremichael, Jiawu Xu, Zoe H. Rogers, Alexander R. Munoz, Samson Okello, June-Ho Kim, Ruth Sentongo, Robert Wagubi, Alex Lankowski, Segametsi Maruapula, Guoyan Zhao, Scott A. Handley, Mosepele Mosepele, Mark J. Siedner, Douglas S. Kwon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract HIV-associated changes in intestinal microbiota are believed to be important drivers of disease progression. However, the majority of studies have focused on populations in high-income countries rather than in developing regions where HIV bu
Externí odkaz:
https://doaj.org/article/b80e9de9b259430eb0c139472099a4e5
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 54-54 (2024)
OBJECTIVES/GOALS: Using the NIH’s expanded definition of underrepresented populations in the biomedical, clinical, behavioral and social science research enterprise, we examined the impediments for conducting translational research experienced by t
Externí odkaz:
https://doaj.org/article/5243f2ed72104f8a8db35c98ea3c4cb9
Autor:
B. J. Kunath, O. Hickl, P. Queirós, C. Martin-Gallausiaux, L. A. Lebrun, R. Halder, C. C. Laczny, T. S. B. Schmidt, M. R. Hayward, D. Becher, A. Heintz-Buschart, C. de Beaufort, P. Bork, P. May, P. Wilmes
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-18 (2022)
Abstract Background Alterations to the gut microbiome have been linked to multiple chronic diseases. However, the drivers of such changes remain largely unknown. The oral cavity acts as a major route of exposure to exogenous factors including pathoge
Externí odkaz:
https://doaj.org/article/c090755a540a4cb1a494be9e9cafb864
Autor:
Alexander Munoz, Matthew R. Hayward, Seth M. Bloom, Muntsa Rocafort, Sinaye Ngcapu, Nomfuneko A. Mafunda, Jiawu Xu, Nondumiso Xulu, Mary Dong, Krista L. Dong, Nasreen Ismail, Thumbi Ndung’u, Musie S. Ghebermichael, Douglas S. Kwon
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-12 (2021)
Abstract Background Cervicovaginal bacterial communities composed of diverse anaerobes with low Lactobacillus abundance are associated with poor reproductive outcomes such as preterm birth, infertility, cervicitis, and risk of sexually transmitted in
Externí odkaz:
https://doaj.org/article/340cfb0828a54631a00c8471991e17eb
Autor:
Elizabeth H. Byrne, Mara Farcasanu, Seth M. Bloom, Nondumiso Xulu, Jiawu Xu, Barry L. Hykes, Nomfuneko A. Mafunda, Matthew R. Hayward, Mary Dong, Krista L. Dong, Thandeka Gumbi, Fransisca Xolisile Ceasar, Nasreen Ismail, Thumbi Ndung’u, Christina Gosmann, Musie S. Ghebremichael, Scott A. Handley, Caroline M. Mitchell, Alexandra-Chloé Villani, Douglas S. Kwon
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The microbiome of the female genital tract (FGT) is closely linked to reproductive health outcomes. Diverse, anaerobe-dominated communities with low Lactobacillus abundance are associated with a number of adverse reproductive outcomes, such as preter
Externí odkaz:
https://doaj.org/article/86849ac40fd74dae97d282ac9d69d495
Autor:
Maya Sangesland, Ashraf S. Yousif, Larance Ronsard, Samuel W. Kazer, Alex Lee Zhu, G. James Gatter, Matthew R. Hayward, Ralston M. Barnes, Maricel Quirindongo-Crespo, Daniel Rohrer, Nils Lonberg, Douglas Kwon, Alex K. Shalek, Daniel Lingwood
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108065- (2020)
Summary: B cell receptors (BCRs) display a combination of variable (V)-gene-encoded complementarity determining regions (CDRs) and adaptive/hypervariable CDR3 loops to engage antigens. It has long been proposed that the former tune for recognition of
Externí odkaz:
https://doaj.org/article/4869d22e49344399b1979bd3c854bad0
Autor:
Alexander Munoz, Matthew R. Hayward, Seth M. Bloom, Muntsa Rocafort, Sinaye Ngcapu, Nomfuneko A. Mafunda, Jiawu Xu, Nondumiso Xulu, Mary Dong, Krista L. Dong, Nasreen Ismail, Thumbi Ndung’u, Musie S. Ghebremichael, Douglas S. Kwon
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/8767b8391bc046219f88b996209baf11
Autor:
Djuro Karanovic, Ian C. Michelow, Anthony R. Hayward, Suk See DeRavin, Ottavia M. Delmonte, Michael E. Grigg, Adam Kerry Dobbs, Julie E. Niemela, Jennifer Stoddard, Zaid Alhinai, Natasha Rybak, Nancy Hernandez, Stefania Pittaluga, Sergio D. Rosenzweig, Gulbu Uzel, Luigi D. Notarangelo
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Phosphoinositide 3-kinase (PI3K) plays an integral role in lymphocyte function. Mutations in PIK3CD and PIK3R1, encoding the PI3K p110δ and p85α subunits, respectively, cause increased PI3K activity and result in immunodeficiency with immune dysreg
Externí odkaz:
https://doaj.org/article/91e24ad155c14f3995e7c86499bc37f9