Zobrazeno 1 - 10
of 54
pro vyhledávání: '"A. R. Dluzewski"'
Autor:
Philippa K Harris, Sharon Yeoh, Anton R Dluzewski, Rebecca A O'Donnell, Chrislaine Withers-Martinez, Fiona Hackett, Lawrence H Bannister, Graham H Mitchell, Michael J Blackman
Publikováno v:
PLoS Pathogens, Vol 1, Iss 3, Pp 241-251 (2005)
Proteolytic shedding of surface proteins during invasion by apicomplexan parasites is a widespread phenomenon, thought to represent a mechanism by which the parasites disengage adhesin-receptor complexes in order to gain entry into their host cell. E
Externí odkaz:
https://doaj.org/article/1183b80983454879893ee7bcda843f01
Autor:
Anton R Dluzewski, Irene T Ling, John M Hopkins, Munira Grainger, Gabriele Margos, Graham H Mitchell, Anthony A Holder, Lawrence H Bannister
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e3085 (2008)
Plasmodium falciparum Merozoite Surface Protein 1 (MSP1) is synthesized during schizogony as a 195-kDa precursor that is processed into four fragments on the parasite surface. Following a second proteolytic cleavage during merozoite invasion of the r
Externí odkaz:
https://doaj.org/article/1696878e513d4620bc744c4d9fd3e3d7
Autor:
Ursula Straschil, Ellen Knuepfer, Oniz Suleyman, Anton R. Dluzewski, Anthony A. Holder, Solabomi A. Ogun, Rita Tewari, Aisling H. O’Keeffe, Munira Grainger, Judith L. Green
Publikováno v:
Cellular Microbiology
Cellular Microbiology; Vol 16
Cellular Microbiology; Vol 16
Apicomplexan parasites invade host cells by a conserved mechanism: parasite proteins are secreted from apical organelles, anchored in the host cell plasma membrane, and then interact with integral membrane proteins on the zoite surface to form the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae124a08fc32f273e5d4c5d4f696d0c
http://europepmc.org/articles/PMC3922828
http://europepmc.org/articles/PMC3922828
Autor:
Louisa McRobert, Anthony A. Holder, Audrey Sicard, Anton R. Dluzewski, Christine S. Hopp, Munira Grainger, Helen M. Taylor, David A. Baker
Publikováno v:
Eukaryotic Cell. 9:37-45
A role for the Plasmodium falciparum cyclic GMP (cGMP)-dependent protein kinase (PfPKG) in gametogenesis in the malaria parasite was elucidated previously. In the present study we examined the role of PfPKG in the asexual blood-stage of the parasite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4c2c2a7707c338d180638c809c3ff5
https://doi.org/10.1128/ec.00186-09
https://doi.org/10.1128/ec.00186-09
Autor:
Anton R. Dluzewski, Graham H. Mitchell, Jennifer C. Pinder, Gabriele Margos, Deborah J. Coles, Jacqueline Chaparro-Olaya, Moisés Wasserman
Publikováno v:
Cell Motility and the Cytoskeleton. 60:200-213
Six myosins genes are now annotated in the Plasmodium falciparum Genome Project. Malaria myosins have been named alphabetically; accordingly, we refer to the two latest additions as Pfmyo-E and Pfmyo-F. Both new myosins contain regions characteristic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fbb36ddda97593503eff3293a94202a
https://doi.org/10.1002/cm.20055
https://doi.org/10.1002/cm.20055
Autor:
Laurence Florens, Osamu Kaneko, Takafumi Tsuboi, Anthony A. Holder, L. H. Bannister, Anton R. Dluzewski, Denise Mattei, Jeffrey R. Johnson, John R. Yates, Motomi Torii, Brian Y. S. Yim Lim, Irene T. Ling, John M. Hopkins, Munira Grainger
Publikováno v:
Molecular Microbiology. 52:107-118
The first gene characterizing the clag (cytoadherence linked asexual gene) family of Plasmodium falciparum was identified on chromosome 9. The protein product (Clag9) was implicated in cytoadhesion, the binding of infected erythrocytes to host endoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cdc719036615eff27a241fc95970af9
https://doi.org/10.1111/j.1365-2958.2003.03969.x
https://doi.org/10.1111/j.1365-2958.2003.03969.x
Publikováno v:
Infection and Immunity. 72:154-158
Apical membrane antigen 1 (AMA-1) of Plasmodium merozoites is established as a candidate molecule for inclusion in a human malaria vaccine and is strongly conserved in the genus. We have investigated its function in merozoite invasion by incubating P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8f1959631355e933908bc309719c11
https://doi.org/10.1128/iai.72.1.154-158.2004
https://doi.org/10.1128/iai.72.1.154-158.2004
Autor:
Jeffrey J. Babon, S. L. Fleck, Berry Birdsall, Michael J. Blackman, Catherine A. Kettleborough, James Feeney, William D. Morgan, Anton R. Dluzewski, Anthony A. Holder, Stephen R. Martin, Evelina Angov
Publikováno v:
Journal of Biological Chemistry. 278:47670-47677
Malarial merozoites invade erythrocytes; and as an essential step in this invasion process, the 42-kDa fragment of Plasmodium falciparum merozoite surface protein-1 (MSP142) is further cleaved to a 33-kDa N-terminal polypeptide (MSP133) and an 19-kDa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a16a526406c7d8dbe646af322073b1c
https://doi.org/10.1074/jbc.m306603200
https://doi.org/10.1074/jbc.m306603200
Autor:
L. H. Bannister, Jacqueline Chaparro-Olaya, Moisés Wasserman, Anton R. Dluzewski, Graham H. Mitchell, Gabriele Margos, Jennifer C. Pinder
Publikováno v:
European Journal of Protistology. 39:423-427
Myosins are motor proteins which, through interaction with filamentous actin, create movement. Multiple myosins have been identified in many of the apicomplexans, however, little is known regarding provenance over the life cycle or biological functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c6cb561c4ea9cf5974ebbfc531ee786
https://doi.org/10.1078/0932-4739-00015
https://doi.org/10.1078/0932-4739-00015
Autor:
Leann Tilley, Alan W. Thomas, Robin F. Anders, Michael Foley, Felomena Li, Anton R. Dluzewski, Andrew M. Coley
Publikováno v:
Journal of Biological Chemistry. 277:50303-50310
Apical membrane antigen-1 (AMA1) is a transmembrane protein present on the surface of merozoites that is thought to be involved in the process of parasite invasion of host erythrocytes. Although it is the target of a natural immune response that can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a3f824c37bb8b5d45d08d7763ec442
https://doi.org/10.1074/jbc.m207985200
https://doi.org/10.1074/jbc.m207985200