Zobrazeno 1 - 4
of 4
pro vyhledávání: '"A. R. Bhagwani"'
Autor:
Aneel R. Bhagwani, Mehboob Ali, Bryce Piper, Mingjun Liu, Jaylen Hudson, Neil Kelly, Srimathi Bogamuwa, Hu Yang, James D. Londino, Joseph S. Bednash, Daniela Farkas, Rama K. Mallampalli, Mark R. Nicolls, John J. Ryan, A.A. Roger Thompson, Stephen Y. Chan, Delphine Gomez, Elena A. Goncharova, Laszlo Farkas
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105935- (2023)
Summary: Pulmonary arterial hypertension (PAH) features pathogenic and abnormal endothelial cells (ECs), and one potential origin is clonal selection. We studied the role of p53 and toll-like receptor 3 (TLR3) in clonal expansion and pulmonary hypert
Externí odkaz:
https://doaj.org/article/8a31db23f5614a919e0d4eb917f3b10d
Autor:
Aneel R Bhagwani, Schuyler Hultman, Daniela Farkas, Rebecca Moncayo, Kaivalya Dandamudi, Arsema K Zadu, Carlyne D Cool, Laszlo Farkas
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213890 (2019)
Uncontrolled proliferation of endothelial cells is essential to the pathogenesis of pulmonary arterial hypertension (PAH). Both proliferation and cytoskeleton reorganization are associated with upregulation of the intermediate filament protein Nestin
Externí odkaz:
https://doaj.org/article/e8c8ed75ac6245148dd33db36adf9bfa
Autor:
Bryce Piper, Srimathi Bogamuwa, Tanvir Hossain, Daniela Farkas, Lorena Rosas, Adam Green, Geoffrey Newcomb, Nuo Sun, Jeffrey C. Horowitz, Aneel R Bhagwani, Hu Yang, Tatiana V. Kudryashova, Mauricio Rojas, Ana L. Mora, Pearlly Yan, Rama K. Mallampalli, Elena A. Goncharova, David M. Eckmann, Laszlo Farkas
Publikováno v:
bioRxiv
Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with limited treatment options. Endothelial dysfunction plays a central role in development and progression of PAH, yet the underlying mechanisms are incompletely understo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9640edb699bc62966ed67a5744c80d1
https://europepmc.org/articles/PMC9915659/
https://europepmc.org/articles/PMC9915659/
Publikováno v:
European journal of trauma and emergency surgery : official publication of the European Trauma Society. 39(4)
Vascular injuries secondary to blunt or penetrating trauma are a significant cause of morbidity and mortality, especially in war-afflicted areas. Due to the violent situations of Pakistan and the unavailability of vascular services in remote areas, w