Zobrazeno 1 - 10
of 210
pro vyhledávání: '"A. R. Donovan"'
Autor:
Karsten Suhre, Guhan Ram Venkataraman, Harendra Guturu, Anna Halama, Nisha Stephan, Gaurav Thareja, Hina Sarwath, Khatereh Motamedchaboki, Margaret K. R. Donovan, Asim Siddiqui, Serafim Batzoglou, Frank Schmidt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Proteogenomics studies generate hypotheses on protein function and provide genetic evidence for drug target prioritization. Most previous work has been conducted using affinity-based proteomics approaches. These technologies face challenges,
Externí odkaz:
https://doaj.org/article/dc36d59054594f129b87e7c28a9978c6
Autor:
Jennifer P. Nguyen, Timothy D. Arthur, Kyohei Fujita, Bianca M. Salgado, Margaret K. R. Donovan, iPSCORE Consortium, Hiroko Matsui, Ji Hyun Kim, Agnieszka D’Antonio-Chronowska, Matteo D’Antonio, Kelly A. Frazer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract The impact of genetic regulatory variation active in early pancreatic development on adult pancreatic disease and traits is not well understood. Here, we generate a panel of 107 fetal-like iPSC-derived pancreatic progenitor cells (iPSC-PPCs)
Externí odkaz:
https://doaj.org/article/17651eb9e70d46c1886f82910dec5f0c
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 7, Iss 4, Pp 913-919 (2022)
Abstract Objective Invasive fungal sinusitis (IFS) in patients with active or recent COVID‐19 have been reported throughout the world. The primary purpose of the systematic review is to describe factors associated with IFS in patients with COVID‐
Externí odkaz:
https://doaj.org/article/8e7ddf65b3ed4ce6a87d5484a6514aaf
Autor:
Margaret K R Donovan, Yingxiang Huang, John E Blume, Jian Wang, Daniel Hornburg, Shadi Ferdosi, Iman Mohtashemi, Sangtae Kim, Marwin Ko, Ryan W Benz, Theodore L Platt, Serafim Batzoglou, Luis A Diaz, Omid C Farokhzad, Asim Siddiqui
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282821 (2023)
Advancements in deep plasma proteomics are enabling high-resolution measurement of plasma proteoforms, which may reveal a rich source of novel biomarkers previously concealed by aggregated protein methods. Here, we analyze 188 plasma proteomes from n
Externí odkaz:
https://doaj.org/article/6ed07386973f45a4bd1241bd71b47825
Publikováno v:
Спортивная медицина: наука и практика, Vol 7, Iss 2, Pp 84-89 (2020)
To improve the effectiveness of the fight against doping, it is necessary to assess the areas of risk of doping in various sports disciplines. Objective: to conduct a survey of Armenian athletes, to assess the impact of social variables on their atti
Externí odkaz:
https://doaj.org/article/3b227c9475a2434694cc403a5dd346c0
Autor:
David Jakubosky, Matteo D’Antonio, Marc Jan Bonder, Craig Smail, Margaret K. R. Donovan, William W. Young Greenwald, Hiroko Matsui, i2QTL Consortium, Agnieszka D’Antonio-Chronowska, Oliver Stegle, Erin N. Smith, Stephen B. Montgomery, Christopher DeBoever, Kelly A. Frazer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Genetic variation associated with gene expression changes has mostly been studied in the context of single nucleotide variants. Here, Jakubosky et al. report eQTL analysis of structural variants and short tandem repeats and find properties, such as l
Externí odkaz:
https://doaj.org/article/3ac8df01ae4c4323ad093a164d82fdc4
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Cellular heterogeneity can confound functional genomics analyses of bulk tissues. Here, Donovan et al. deconvolute bulk GTEx RNA-seq data utilizing scRNA-seq data from the Tabula Muris project and show the power of using cell populations in eQTL anal
Externí odkaz:
https://doaj.org/article/bf4f52ec9de84c23838bce86931d7b44
Autor:
Matteo D'Antonio, Jennifer P Nguyen, Timothy D Arthur, Hiroko Matsui, Margaret K R Donovan, Agnieszka D'Antonio-Chronowska, Kelly A Frazer
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2, p e1009918 (2022)
Reactivation of fetal-specific genes and isoforms occurs during heart failure. However, the underlying molecular mechanisms and the extent to which the fetal program switch occurs remains unclear. Limitations hindering transcriptome-wide analyses of
Externí odkaz:
https://doaj.org/article/9db7d6f61c9c4402989534ec503a0a50
Autor:
Rodrigo Wiff, Andrés Flores, Santiago Gacitúa, Carl R. Donovan, T. Mariella Canales, Mauricio Ahumada, Dante Queirolo
Publikováno v:
Latin American Journal of Aquatic Research. 51:34-46
The southern rays bream (Brama australis) is a highly migratory, epi-mesopelagic species supporting an important artisanal fishery off central-southern Chile. Despite its importance, several questions exist about this species's demography and migrato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b2d1bf452f1fa8eeb7243e22060e209
https://doi.org/10.3856/vol51-issue1-fulltext-2950
https://doi.org/10.3856/vol51-issue1-fulltext-2950
Autor:
A.S Hovhannisyan, G.G. Sahakyan, T. Ukleba, E. Arhip, G. Jalleh, R. Donovan, Areg Hovhannisyan
Publikováno v:
Գիտությունը սպորտում. արդի հիմնախնդիրներ. :166-183
The aim of the study is investigation of the level, similarities and differences of coaches and athletes anti-doping knowledge in Armenia, Georgia and Moldova to identify the essential components of an education program for coaches to ensure coaches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fbadbeadbd3d363d06377d301492965
https://doi.org/10.53068/25792997-2022.3.7-66
https://doi.org/10.53068/25792997-2022.3.7-66