Zobrazeno 1 - 10
of 111
pro vyhledávání: '"A. R., Opoku"'
Publikováno v:
Electronic Journal of Biotechnology, Vol 68, Iss , Pp 67-80 (2024)
Background: Alzheimer’s disease (AD) is the most common form of dementia and dementia constitutes the fifth leading cause of mortality across the globe. Available treatment modalities and drugs have abysmally failed to curtail AD. This study evalua
Externí odkaz:
https://doaj.org/article/861a9b6d874443bcb133ebc9294281fe
Autor:
Musawenkosi Ndlovu, June C. Serem, Mamoalosi A. Selepe, Andrew R. Opoku, Megan J. Bester, Zeno Apostolides, Rebamang A. Mosa
Publikováno v:
ACS Omega, Vol 8, Iss 34, Pp 30906-30916 (2023)
Externí odkaz:
https://doaj.org/article/9c0757f98dfc4591871b6cbd51dda1b4
Autor:
Musawenkosi Ndlovu, June C. Serem, Megan J. Bester, Zeno Apostolides, Andrew R. Opoku, Rebamang A. Mosa
Publikováno v:
Journal of Lipids, Vol 2024 (2024)
Triterpenoids have been identified as potential novel lipid-lowering drugs for the treatment of hypertriglyceridemia. This study investigated the potential antilipogenic and/or antilipolytic effects of two triterpenoids (ARM-2 and RA-5) isolated from
Externí odkaz:
https://doaj.org/article/696f99832d46459699d7d5e847ce52c9
Autor:
Albert O. Ikhane, Siphesihle Z. Sithole, Nkosinathi D. Cele, Foluso O. Osunsanmi, Rebamang A. Mosa, Andrew R. Opoku
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 608 (2024)
Cyanobacteria in recent times have been touted to be a suitable source for the discovery of novel compounds, including antioxidants and antibiotics, due to their large arsenal of metabolites. This study presents the in vitro antioxidant and in silico
Externí odkaz:
https://doaj.org/article/3cc787e83c2140eab43244aff92d43ee
Autor:
Zoxolo N. Nyaba, Pretty Murambiwa, Andy R. Opoku, Samson Mukaratirwa, Francis O. Shode, Mthokozisi B. C. Simelane
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-8 (2018)
Abstract Background Malaria continues to be a global burden as the efficacy of most commercial anti-malarial drugs has been compromised by the evolution of parasite resistance. With the urgent need created for the development of alternative and more
Externí odkaz:
https://doaj.org/article/1bb6d593bcfc46f3b5b4e7f8f2a99a0d
Autor:
Victor O. Fadipe, Nkoana I. Mongalo, Andy R. Opoku, Preachers M. Dikhoba, Tshepiso J. Makhafola
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 17, Iss 1, Pp 1-6 (2017)
Abstract Background Tuberculosis is counted amongst the most infectious and lethal illnesses worldwide and remains one of the major threats to human health. The aim of the current study was to isolate and characterize anti-mycobacterial compounds pre
Externí odkaz:
https://doaj.org/article/c29309ab49dc4380aac51afc9becf335
Autor:
Sithandiwe E Mazibuko-Mbeje, Phiwayinkosi V Dludla, Rabia Johnson, Elizabeth Joubert, Johan Louw, Khanyisani Ziqubu, Luca Tiano, Sonia Silvestri, Patrick Orlando, Andy R Opoku, Christo J F Muller
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216172 (2019)
Aspalathin is a rooibos flavonoid with established blood glucose lowering properties, however, its efficacy to moderate complications associated with hepatic insulin resistance is unknown. To study such effects, C3A liver cells exposed to palmitate w
Externí odkaz:
https://doaj.org/article/246e00eb09e3449ca7720565ad836b7c
Autor:
Sindiswa L. Dube, Foluso O. Osunsanmi, Bongekile P. Ngcobo, Londiwe B. Mkhwanazi, Zanele Z. Jobe, Raphael T. Aruleba, Rebamang A. Mosa, Andrew R. Opoku
Publikováno v:
Polish Journal of Microbiology.
Lignin recalcitrance is a key issue in producing value-added products from lignocellulose biomass. In situ biodegradable lignin-modifying enzymes-producing bacteria are considered a suitable solution to lignin biodegradation problems, but exploitatio
Autor:
Rebamang A. Mosa, Nkosinathi D. Cele, Sihle E. Mabhida, Samkelisiwe C. Shabalala, Dambudzo Penduka, Andy R. Opoku
Publikováno v:
Molecules, Vol 20, Iss 7, Pp 13374-13383 (2015)
Control of postprandial hyperglycemia is crucial in the management of diabetes mellitus. Despite the use of the current hypoglycemic drugs, incidence of diabetes and related diseases continue to increase. This study aimed at evaluating the in vivo an
Externí odkaz:
https://doaj.org/article/245ecbe9721047f3a7ce3da4130a14e4
Autor:
Michael Chukwuka Ojo, Godfrey E. Zaharare, Foluso Oluwagbemiga Osunsanmi, Andy R. Opoku, Rebamang A. Mosa, Nkosinathi David Cele
Publikováno v:
Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas. 20:416-426
Reactive oxygen species are implicated in multiple pathological conditions including erectile dysfunction. This study evaluated the in vitro and in vivo antioxidant potential of the methanolic extracts of Inula glomerata and Salacia kraussii. The pla