GABAergic inhibition in dual-transmission cholinergic and GABAergic striatal interneurons is abolished in Parkinson disease

Autor: N. Lozovaya, S. Eftekhari, R. Cloarec, L. A. Gouty-Colomer, A. Dufour, B. Riffault, M. Billon-Grand, A. Pons-Bennaceur, N. Oumar, N. Burnashev, Y. Ben-Ari, C. Hammond

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)

Cholinergic interneurons of the striatum are involved reward-related behaviors and have been implicated in Parkinson’s disease. Here the authors report that half of cholinergic neurons co-release acetylcholine and GABA, and study the role of these

Externí odkaz: https://doaj.org/article/6462473cc62646758946f586af2ca644

GABAergic inhibition in dual-transmission cholinergic and GABAergic striatal interneurons is abolished in Parkinson disease

Autor: M. Billon-Grand, Robin Cloarec, Laurie-Anne Gouty-Colomer, N. Oumar, Amandine Dufour, Alexandre Pons-Bennaceur, Constance Hammond, Yehezkel Ben-Ari, Sanaz Eftekhari, Baptiste Riffault, Nail Burnashev, Natalia Lozovaya

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-03802-y⟩
Cell Stress

The rule of one terminal and one transmitter acting on one synapse clearly fails to cover the complexity of chemical synapse operation in the brain. Compelling evidence now indicates that two transmitters can be released from the same terminal, actin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3520e938d7110f82ef90cd7e8dac782a
https://doaj.org/article/6462473cc62646758946f586af2ca644

Early alterations in a mouse model of Rett syndrome: the GABA developmental shift is abolished at birth

Autor: M. Billon-Grand, Jean-Luc Gaiarsa, Damien Guimond, Sanaz Eftekhari, Roman Tyzio, Paolo Bonifazi, Yehezkel Ben-Ari, Natalia Lozovaya, Alexandre Pons-Bennaceur, Javier Rasero, T.-T. Bui, Diana C. Ferrari, Morgane Chiesa, Romain Nardou

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9, pp.9276. ⟨10.1038/s41598-019-45635-9⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)

Genetic mutations of the Methyl-CpG-binding protein-2 (MECP2) gene underlie Rett syndrome (RTT). Developmental processes are often considered to be irrelevant in RTT pathogenesis but neuronal activity at birth has not been recorded. We report that th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00fc2e8c06c988381445a2186a3f197
https://doi.org/10.1038/s41598-019-45635-9

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Les mécanismes antiépileptiques de l'AppCH2ppA dans la sclérose tubéreuse de Bourneville

Autor: Pons Bennaceur, Alexandre

La Sclérose Tubéreuse de Bourneville est une pathologie génétique rare qui se caractérise par la survenue de crises épileptiques précoces à l’origine du développement de nombreux troubles neurologiques tels que des symptômes autistiques o

Externí odkaz: http://www.theses.fr/2018AIXM0303