Zobrazeno 1 - 10
of 2 894
pro vyhledávání: '"A. Paul Kelly"'
Autor:
Ioanna Tzani, Marina Castro-Rivadeneyra, Paul Kelly, Lisa Strasser, Lin Zhang, Martin Clynes, Barry L. Karger, Niall Barron, Jonathan Bones, Colin Clarke
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Chinese hamster ovary (CHO) cells are used to produce almost 90% of therapeutic monoclonal antibodies (mAbs) and antibody fusion proteins (Fc-fusion). The annotation of non-canonical translation events in these cellular factories remains inc
Externí odkaz:
https://doaj.org/article/5f963831bb07487b811c1a7ac3b1468f
Autor:
Karen Milton, Graham Baker, Claire L. Cleland, Andy Cope, Ruth F. Hunter, Ruth Jepson, Frank Kee, Paul Kelly, Andrew J. Williams, Michael P. Kelly
Publikováno v:
Health Research Policy and Systems, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background In 2016, large-scale 20 miles per hour speed limits were introduced in the United Kingdom cities of Edinburgh and Belfast. This paper investigates the role that scientific evidence played in the policy decisions to implement lower
Externí odkaz:
https://doaj.org/article/e2ffa841934d4ceaaadaf1b9c21360f3
Autor:
Jennifer Welsh, Grace Joshy, Rachel Freeman-Robinson, Nicholas Biddle, Emily Banks, Clement Schlegel, Kayla Jordan, Phillip Gould, Paul Kelly, Rosemary Korda
Publikováno v:
International Journal of Population Data Science, Vol 9, Iss 5 (2024)
Aim To quantify the impact of the pandemic on fatal burden of disease among those living in residential aged care homes (RACH) in Australia. Methods Using Residential Aged Care data linked to Death Registrations (Jan 2016 to 11 Aug 2022), we estim
Externí odkaz:
https://doaj.org/article/7c7f9a526a0f4e299a33dc72a3260c7b
Publikováno v:
JMIR Cancer, Vol 10, p e54785 (2024)
BackgroundPhysical activity engagement following a cancer diagnosis is positively associated with survival, reduced risk of disease recurrence, and reduced cancer-specific and all-cause mortality. However, rates of physical activity engagement are lo
Externí odkaz:
https://doaj.org/article/eee4e4eabd26442585f4cd6748d69bb2
Autor:
Pekka Oja, Aamir Raoof Memon, Sylvia Titze, Danijel Jurakic, Si-Tong Chen, Nipun Shrestha, Sowannry Em, Tena Matolic, Tommi Vasankari, Ari Heinonen, Jozo Grgic, Pasi Koski, Sami Kokko, Paul Kelly, Charlie Foster, Hrvoje Podnar, Zeljko Pedisic
Publikováno v:
Sports Medicine - Open, Vol 10, Iss 1, Pp 1-17 (2024)
Abstract Background Several reviews have examined the health benefits of participation in specific sports, such as baseball, cricket, cross-country skiing, cycling, downhill skiing, football, golf, judo, rugby, running and swimming. However, new prim
Externí odkaz:
https://doaj.org/article/4a6a706c24124fddb89ca70d407bf8db
Autor:
Ceri Evans, Kuda Mutasa, Sandra Rukobo, Margaret Govha, Patience Mushayanembwa, Bernard Chasekwa, Florence D. Majo, Naume V. Tavengwa, Jonathan Broad, Christie Noble, Ethan K. Gough, Paul Kelly, Claire D. Bourke, Jean H. Humphrey, Robert Ntozini, Andrew J. Prendergast
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Children who are HIV-exposed but uninfected have increased infectious mortality compared to HIV-unexposed children, raising the possibility of immune abnormalities following exposure to maternal viraemia, immune dysfunction, and co-infection
Externí odkaz:
https://doaj.org/article/24a5828e11cb4ab6a03eddb2dabe2347
Autor:
Kanta Chandwe, Mutsa Bwakura-Dangarembizi, Beatrice Amadi, Gertrude Tawodzera, Deophine Ngosa, Anesu Dzikiti, Nivea Chulu, Robert Makuyana, Kanekwa Zyambo, Kuda Mutasa, Chola Mulenga, Ellen Besa, Jonathan P. Sturgeon, Shepherd Mudzingwa, Bwalya Simunyola, Lydia Kazhila, Masuzyo Zyambo, Hazel Sonkwe, Batsirai Mutasa, Miyoba Chipunza, Virginia Sauramba, Lisa Langhaug, Victor Mudenda, Simon H. Murch, Susan Hill, Raymond J. Playford, Kelley VanBuskirk, Andrew J. Prendergast, Paul Kelly
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Malnutrition underlies almost half of all child deaths globally. Severe Acute Malnutrition (SAM) carries unacceptable mortality, particularly if accompanied by infection or medical complications, including enteropathy. We evaluated four inte
Externí odkaz:
https://doaj.org/article/159806405f4445f19bc5db50366e7152
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Introduction There are uncertainties surrounding the spectrum of upper gastrointestinal (UGI) diseases in sub-Saharan Africa. This is mainly due to the limitations of data collection and recording. We previously reported an audit of UGI endo
Externí odkaz:
https://doaj.org/article/1814c05c56df4f259df6e13d7dd9a1cb
Autor:
Robert Olson, Hadassah Abraham, Curtis Leclerc, Alexander Benny, Sarah Baker, Quinn Matthews, Nick Chng, Alanah Bergman, Benjamin Mou, Emma M. Dunne, Devin Schellenberg, Will Jiang, Elisa Chan, Siavash Atrchian, Shilo Lefresne, Hannah Carolan, Boris Valev, Scott Tyldesley, Andrew Bang, Tanya Berrang, Haley Clark, Fred Hsu, Alexander V. Louie, Andrew Warner, David A. Palma, Doris Howell, Aisling Barry, Laura Dawson, Petra Grendarova, Debra Walker, Rishi Sinha, Jillian Tsai, Houda Bahig, Isabelle Thibault, Rashmi Koul, Sashendra Senthi, Iain Phillips, Derek Grose, Paul Kelly, John Armstrong, Ronan McDermott, Candice Johnstone, Srini Vasan, Noel Aherne, Stephen Harrow, Mitchell Liu
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Radiotherapy delivery regimens can vary between a single fraction (SF) and multiple fractions (MF) given daily for up to several weeks depending on the location of the cancer or metastases. With limited evidence comparing fraction
Externí odkaz:
https://doaj.org/article/4f87355d9b904d85b0fb9be81c1c6304
Autor:
Fatima Zulqarnain, Xueheng Zhao, Kenneth D.R. Setchell, Yash Sharma, Phillip Fernandes, Sanjana Srivastava, Aman Shrivastava, Lubaina Ehsan, Varun Jain, Shyam Raghavan, Christopher Moskaluk, Yael Haberman, Lee A. Denson, Khyati Mehta, Najeeha T. Iqbal, Najeeb Rahman, Kamran Sadiq, Zubair Ahmad, Romana Idress, Junaid Iqbal, Sheraz Ahmed, Aneeta Hotwani, Fayyaz Umrani, Beatrice Amadi, Paul Kelly, Donald E. Brown, Sean R. Moore, Syed Asad Ali, Sana Syed
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110013- (2024)
Summary: Environmental enteric dysfunction (EED) is a subclinical enteropathy challenging to diagnose due to an overlap of tissue features with other inflammatory enteropathies. EED subjects (n = 52) from Pakistan, controls (n = 25), and a validation
Externí odkaz:
https://doaj.org/article/fd58342bfb344c5fb6b60bc3741829b1