Zobrazeno 1 - 10
of 53
pro vyhledávání: '"A. P. Ollapally"'
Publikováno v:
Asian Journal of Medical Sciences, Vol 15, Iss 10, Pp 22-27 (2024)
Background: Post-operative sore throat (POST) can be a cause of great discomfort after endotracheal intubation with an incidence of up to 65%. While there are studies demonstrating the efficacy of prophylactic zinc lozenges in decreasing POST in pati
Externí odkaz:
https://doaj.org/article/61d8ac49601b405fbf44feddcf204dad
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 17, Iss 8, Pp 01-04 (2023)
Introduction: Caudal epidural block is a popular regional anesthetic technique in children undergoing infraumbilical surgeries. Conventionally, a landmark-guided method is used to perform caudal epidural blocks. Although widely practiced, this me
Externí odkaz:
https://doaj.org/article/4146bdf1dfeb4f48845a95c08b0f9159
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 10, Iss 12, Pp UC01-UC04 (2016)
Introduction: Sensory blockade of the brachial plexus with local anaesthetics for perioperative analgesia leads to stable haemodynamics intraoperatively, smoother emergence from general anaesthesia and decreased need for supplemental analgesics o
Externí odkaz:
https://doaj.org/article/abc5ac86e1d94c90bc0bb17ebf34399e
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 21:327-334
Direct oxidation of 5-fluoro-1-(4-O-acetyl-3-deoxy-3-fluoro-6-O-trityl-beta-D-glucopyranosyl) uracil 9 led to the title compound 10 after a beta-elimination reaction. The formation of the hydrate of ketone 10 due to the highly electronegative fluorin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9515c3d4cfe339646e88a8fc7719a47f
https://doi.org/10.1081/ncn-120006828
https://doi.org/10.1081/ncn-120006828
SYNTHESIS OF 3′-AZIDO-2′,3′- DIDEOXY-4′-KETOHEXOPYRANOID ANALOGUES AS POSSIBLE ANTIVIRAL NUCLEOSIDES
Publikováno v:
Synthetic Communications. 32:1023-1030
Peracetylated 2-deoxy-D-glucose was coupled with silylated bases. The product was deacetylated and the 4′,6′-hydroxy groups were then protected. An azido group was introduced at the 3′-carbon via tosylation, followed by deprotection, tritylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7a31fc1ae88840782c5f2f61f973911
https://doi.org/10.1081/scc-120003150
https://doi.org/10.1081/scc-120003150
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 20:759-762
Peracetylated alpha-D-glucose was coupled with silylated 5-chlorouracil. The product (2) was deacetylated and 4',6'-hydroxyls were then protected with 4',6'-O-isopropylidene group. Fluorine was introduced at the 3'-position, followed by acetylation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe9b9c7bb0c71d8f9461c4f716de722
https://doi.org/10.1081/ncn-100002424
https://doi.org/10.1081/ncn-100002424
Publikováno v:
Nucleosides and Nucleotides. 15:899-906
A convenient and high yielding procedure is described for a direct conversion of thymidine (1) into 2,3′-anhydrothymidine (2) using the Mitsunobu reaction. Isolation and characterization of two new compounds, 3 and 4, are discussed. AZT has been sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39457dd811399ac020d6eabd87afc2ec
https://doi.org/10.1080/07328319608002136
https://doi.org/10.1080/07328319608002136
Publikováno v:
Nucleosides and Nucleotides. 13:1843-1853
Alkyl steroidal AZT 5′-monophosphate triesters are designed as lipophilic prodrugs of AZT to improve its therapeutic efficiency. We have synthesized four phosphotriesters of AZT, in one-pot, using phosphoramidite-phosphite triester methodology. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e3507994d2f7af51b133d92f5880b66
https://doi.org/10.1080/15257779408010667
https://doi.org/10.1080/15257779408010667
Publikováno v:
Antiviral Chemistry and Chemotherapy. 4:93-96
In order to enhance the therapeutic efficacy of azidothymidine (AZT) by improving its pharmacokinetic properties, three prodrugs of AZT were synthesized by esterifying the 5′-hydroxyl of AZT with three pharmacologically inactive steroidal 17β-carb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46b4dc3734c161c17522f43a331f6238
https://doi.org/10.1177/095632029300400203
https://doi.org/10.1177/095632029300400203
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60c1b60667defdd214856f8f26d447bb
https://doi.org/10.1002/chin.199942245
https://doi.org/10.1002/chin.199942245