Zobrazeno 1 - 10
of 77
pro vyhledávání: '"A. P. M. Brouwer"'
Autor:
J. Hebisch, A.-C. Ghassemieh, E. Zhecheva, M. Brouwer, S. van Gaal, L. Schwabe, T. H. Donner, J.W. de Gee
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The arousal systems of the brainstem, specifically the locus coeruleus-noradrenaline system, respond “phasically” during decisions. These central arousal transients are accompanied by dilations of the pupil. Mechanistic attempts to under
Externí odkaz:
https://doaj.org/article/cc86ddde37fe47a9b5eb719c3a1dffaa
Autor:
Lauge Holm Sørensen, Susanne Karlsmose Pedersen, Jacob Dyring Jensen, Niamh Lacy-Roberts, Athina Andrea, Michael S. M. Brouwer, Kees T. Veldman, Yan Lou, Maria Hoffmann, Rene S. Hendriksen
Publikováno v:
mSystems, Vol 9, Iss 9 (2024)
ABSTRACT As antimicrobial resistance (AMR) surveillance shifts to genomics, ensuring the quality of whole-genome sequencing (WGS) data produced across laboratories is critical. Participation in genomic proficiency tests (GPTs) not only increases indi
Externí odkaz:
https://doaj.org/article/ac0fb612ce65470aaed0fa33bfc40c09
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
IntroductionDiet quality indices provide a quick indicator of overall diet and are commonly used in research and surveillance. We developed a Dutch Healthy Diet for pregnant women (DHD-P) index, comprising 22 components aligned with the 2021 Dutch fo
Externí odkaz:
https://doaj.org/article/9e378b282b584594b10f945d9c480e00
Autor:
Mathieu Gand, Indre Navickaite, Lee-Julia Bartsch, Josephine Grützke, Søren Overballe-Petersen, Astrid Rasmussen, Saria Otani, Valeria Michelacci, Bosco Rodríguez Matamoros, Bruno González-Zorn, Michael S. M. Brouwer, Lisa Di Marcantonio, Bram Bloemen, Kevin Vanneste, Nancy H. C. J. Roosens, Manal AbuOun, Sigrid C. J. De Keersmaecker
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Metagenomic sequencing is a promising method that has the potential to revolutionize the world of pathogen detection and antimicrobial resistance (AMR) surveillance in food-producing environments. However, the analysis of the huge amount of data obta
Externí odkaz:
https://doaj.org/article/d729b54ffaea4748a812efb99acaf3dc
Autor:
Adam J. Ronk, Nicole M. Lloyd, Min Zhang, Caroline Atyeo, Hailee R. Perrett, Chad E. Mire, Kathryn M. Hastie, Rogier W. Sanders, Philip J. M. Brouwer, Erica Olmann Saphire, Andrew B. Ward, Thomas G. Ksiazek, Juan Carlos Alvarez Moreno, Harshwardhan M. Thaker, Galit Alter, Sunny Himansu, Andrea Carfi, Alexander Bukreyev
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Lassa virus is a member of the Arenaviridae family, which causes human infections ranging from asymptomatic to severe hemorrhagic disease with a high case fatality rate. We have designed and generated lipid nanoparticle encapsulated, modifie
Externí odkaz:
https://doaj.org/article/4afd193033d54672afc7fc5b00f7b333
Autor:
Carlo P. J. M. Brouwer, Bart Theelen, Youp van der Linden, Nick Sarink, Mahfuzur Rahman, Saleh Alwasel, Claudia Cafarchia, Mick M. Welling, Teun Boekhout
Publikováno v:
Antibiotics, Vol 13, Iss 8, p 790 (2024)
Objective: The increasing resistance of Malassezia yeasts against commonly used antifungal drugs dictates the need for novel antifungal compounds. Human lactoferrin-based peptides show a broad spectrum of antimicrobial activities. Various assays were
Externí odkaz:
https://doaj.org/article/61a09555041d480a8dd918812150d5f0
Autor:
Inga Petersohn, Anneke H. Hellinga, Linde van Lee, Nicole Keukens, Louis Bont, Kasper A. Hettinga, Edith J. M. Feskens, Elske M. Brouwer-Brolsma
Publikováno v:
Frontiers in Nutrition, Vol 10 (2024)
ContextExclusive breastfeeding for 6 months after birth provides infants with the best start for life. A review by Bravi et al. summarized the importance of maternal diet as a determinant of human milk composition based on data up to 2015, but eviden
Externí odkaz:
https://doaj.org/article/78b1a931afc743eaafdcd5b020adb9e9
Autor:
Novita D. Naomi, Joy Ngo, Elske M. Brouwer-Brolsma, Marion E. C. Buso, Sabita S. Soedamah-Muthu, Carmen Pérez-Rodrigo, Joanne A. Harrold, Jason C. G. Halford, Anne Raben, Johanna M. Geleijnse, Lluis Serra-Majem, Edith J. M. Feskens
Publikováno v:
Nutrition & Diabetes, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Background Sweetened beverage intake may play a role in non-alcoholic fatty liver disease (NAFLD) development, but scientific evidence on their role is limited. This study examined associations between sugar-sweetened beverages (SSB), low/no
Externí odkaz:
https://doaj.org/article/fe1475ed5c9a43bca6dbccc27ba08d7c
Autor:
Kwinten Sliepen, Laura Radić, Joan Capella-Pujol, Yasunori Watanabe, Ian Zon, Ana Chumbe, Wen-Hsin Lee, Marlon de Gast, Jelle Koopsen, Sylvie Koekkoek, Iván del Moral-Sánchez, Philip J. M. Brouwer, Rashmi Ravichandran, Gabriel Ozorowski, Neil P. King, Andrew B. Ward, Marit J. van Gils, Max Crispin, Janke Schinkel, Rogier W. Sanders
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
E1E2 spike on the hepatitis C virion is an important target for vaccine design. Here, the authors permute the subunits to generate E2E1 immunogens and show that mosaic nanoparticles displaying different E2E1 antigens elicit cross-neutralizing antibod
Externí odkaz:
https://doaj.org/article/4bc99bb0318e4c848fb64b60030bf5d0
Vitamin D status modulates mitochondrial oxidative capacities in skeletal muscle: role in sarcopenia
Autor:
Jérôme Salles, Audrey Chanet, Christelle Guillet, Anouk MM. Vaes, Elske M. Brouwer-Brolsma, Christophe Rocher, Christophe Giraudet, Véronique Patrac, Emmanuelle Meugnier, Christophe Montaurier, Philippe Denis, Olivier Le Bacquer, Adeline Blot, Marion Jourdan, Yvette Luiking, Matthew Furber, Miriam Van Dijk, Nicolas Tardif, Y. Yves Boirie, Stéphane Walrand
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Vitamin D has an impact on mitochondrial biogenesis and oxidative activity in skeletal muscle both in vitro and in vivo, and vitamin D supplementation in older people may improve muscle mass and strength.
Externí odkaz:
https://doaj.org/article/213be410b7b44836a4ae8fb3a99381c7