Výsledky vyhledávání - "A. P. F. Trombone"

Akademický článek

Potential of AKR1B10 as a Biomarker and Therapeutic Target in Type 2 Leprosy Reaction

Autor: Cleverson T. Soares, Luciana R. V. Fachin, Ana P. F. Trombone, Patricia S. Rosa, Cássio C. Ghidella, Andrea F. F. Belone

Publikováno v: Frontiers in Medicine, Vol 5 (2018)

The AKR1B10 (aldo-keto reductase family 1 member B10) gene has important functions in carcinogen-induced neoplasia. AKR1B10 is also expressed in type 2 reaction leprosy patients (R2). We measured the expression of AKR1B10 in the skin lesions of patie

Externí odkaz: https://doaj.org/article/d55d938febd540cd87f09da3aaca57f0

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Akademický článek

Differential Expression of MicroRNAs in Leprosy Skin Lesions

Autor: Cleverson T. Soares, Ana P. F. Trombone, Luciana R. V. Fachin, Patricia S. Rosa, Cássio C. Ghidella, Rodrigo F. Ramalho, Mabel G. Pinilla, Alex F. Carvalho, Dirce N. Carrara, Fernando A. Soares, Andrea F. F. Belone

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

Leprosy, a chronic infectious disease caused by Mycobacterium leprae, is a major public health problem in poor and developing countries of the Americas, Africa, and Asia. MicroRNAs (miRNAs), which are small non-coding RNAs (18–24 nucleotides), play

Externí odkaz: https://doaj.org/article/4140e68a69b34f2d8db952a84fb0d5e4

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Akademický článek

Analysis of Immune Response Markers in Jorge Lobo's Disease Lesions Suggests the Occurrence of Mixed T Helper Responses with the Dominance of Regulatory T Cell Activity.

Autor: Michelle de C S Azevedo, Patricia S Rosa, Cleverson T Soares, Luciana R V Fachin, Ida Maria F D Baptista, William J Woods, Gustavo P Garlet, Ana Paula F Trombone, Andrea de F F Belone

Publikováno v: PLoS ONE, Vol 10, Iss 12, p e0145814 (2015)

Jorge Lobo's disease (JLD) is a chronic infection that affects the skin and subcutaneous tissues. Its etiologic agent is the fungus Lacazia loboi. Lesions are classified as localized, multifocal, or disseminated, depending on their location. Early di

Externí odkaz: https://doaj.org/article/8d17635f8e014fbe90ba29e858a42dc0

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Akademický článek

Resposta imune a doenças infecciosas

Autor: Arlete A. M. Coelho-Castelo, Ana P. F. Trombone, Carolina D. Rocha, Julio C. C. Lorenzi

Publikováno v: Medicina, Vol 42, Iss 2 (2009)

A interação do sistema imune com os agentes infecciosos ocorre de uma maneira dinâmica, com mecanismos de controle da infecção e de escape sofisticados. A compreensão dessa complexidade é condição sine qua non para que se estabeleça uma aç

Externí odkaz: https://doaj.org/article/fefc4e11c6f44e40bef1161a2f4dd71e

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Akademický článek

Endocytosis of DNA-Hsp65 alters the pH of the late endosome/lysosome and interferes with antigen presentation.

Autor: Ana Paula F Trombone, Célio L Silva, Karla M Lima, Constance Oliver, Maria Célia Jamur, Alan R Prescott, Arlete A M Coelho-Castelo

Publikováno v: PLoS ONE, Vol 2, Iss 9, p e923 (2007)

BACKGROUND: Experimental models using DNA vaccine has shown that this vaccine is efficient in generating humoral and cellular immune responses to a wide variety of DNA-derived antigens. Despite the progress in DNA vaccine development, the intracellul

Externí odkaz: https://doaj.org/article/c0f1f578aa4f4ad08d77c6880a7843b6

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B cells expressing IL-10 mRNA modulate memory T cells after DNA-Hsp65 immunization

Autor: R. L. L. Silva, Ademilson Panunto-Castelo, Célio Lopes Silva, Isabela C Fontoura, Arlete Aparecida Martins Coelho-Castelo, A. P. F. Trombone, W. Schluchting, Julio C. C. Lorenzi, Thiago Malardo, E. Padilha, Ana Flávia Gembre, Renata Ariza Marques Rossetti, J. E. C. Fiuza, L. R. Almeida

Publikováno v: Brazilian Journal of Medical and Biological Research v.48 n.12 2015
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Brazilian Journal of Medical and Biological Research, Vol 48, Iss 12, Pp 1095-1100 (2015)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Medical and Biological Research, Volume: 48, Issue: 12, Pages: 1095-1100, Published: 18 SEP 2015

In DNA vaccines, the gene of interest is cloned into a bacterial plasmid that is engineered to induce protein production for long periods in eukaryotic cells. Previous research has shown that the intramuscular immunization of BALB/c mice with a naked

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1fb4b3dc0502c91f9704a5224c0d50
https://doi.org/10.1590/1414-431x20154409

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Antigen-presenting cells transfected with Hsp65 messenger RNA fail to treat experimental tuberculosis

Autor: Simone G. Ramos, Carolina D. Rocha, Célio Lopes Silva, A. P. F. Trombone, Luciana P Almeida, Julio C. C. Lorenzi, Ana Flávia Gembre, Everton Padilha, Arlete Aparecida Martins Coelho-Castelo

Publikováno v: Brazilian Journal of Medical and Biological Research
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

In the last several years, the use of dendritic cells has been studied as a therapeutic strategy against tumors. Dendritic cells can be pulsed with peptides or full-length protein, or they can be transfected with DNA or RNA. However, comparative stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6132e61490ca9b8d9b895e7af6d4e91d
https://doi.org/10.1590/s0100-879x2012007500148

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Inhibition of the myotoxic activity of Bothrops jararacussu venom and its two major myotoxins, BthTX-I and BthTX-II, by the aqueous extract of Tabernaemontana catharinensis A. DC. (Apocynaceae)

Autor: A. P. F. Trombone, Aureo Evangelista Santana, Isis do Carmo Kettelhut, Gervásio Henrique Bechara, Adélia Cristina Oliveira Cintra, Elen Landgraf Guiguer Veronese, Luis Everton Esmeraldino, José Roberto Giglio, Suely Vilela Sampaio

Publikováno v: Phytomedicine : international journal of phytotherapy and phytopharmacology. 12(1-2)

Partial neutralization of the myotoxic effect of Bothrops jararacussu venom (BV) and two of its myotoxins [bothropstoxin-I (BthTX-I), catalytically inactive, and II (BthTX-II), showing low PLA2 activity], by the lyophilized aqueous extract of Taberna

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da545a9cf1d2e386460871df806380e
https://pubmed.ncbi.nlm.nih.gov/15693719

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Use of a chimeric ELISA to investigate immunoglobulin E antibody responses to Der p 1 and Der p 2 in mite-allergic patients with asthma, wheezing and/or rhinitis

Autor: A P F, Trombone, K R C, Tobias, V P L, Ferriani, J, Schuurman, R C, Aalberse, A M, Smith, M D, Chapman, L K, Arruda

Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 32(9)

Sensitization to indoor allergens, particularly to dust mites, is a strong risk factor for asthma in children and adults. Assessment of sensitization is carried out using in vivo and in vitro tests to detect specific IgE antibodies.To investigate IgE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::03b04537d271385f14a98f560d707527
https://pubmed.ncbi.nlm.nih.gov/12220471

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