Zobrazeno 1 - 10
of 20
pro vyhledávání: '"A. O. Sosnovtseva"'
Autor:
Aleksei A. Stepanenko, Anastasiia O. Sosnovtseva, Marat P. Valikhov, Anastasia A. Chernysheva, Olga V. Abramova, Konstantin A. Pavlov, Vladimir P. Chekhonin
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The effectiveness of tumor therapy, especially immunotherapy and oncolytic virotherapy, critically depends on the activity of the host immune cells. However, various local and systemic mechanisms of immunosuppression operate in cancer patients. Tumor
Externí odkaz:
https://doaj.org/article/321bf932394c499e8fdc9ef5e98c825e
Autor:
Aleksei A. Stepanenko, Anastasiia O. Sosnovtseva, Marat P. Valikhov, Anastasia A. Chernysheva, Olga V. Abramova, Victor A. Naumenko, Vladimir P. Chekhonin
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Despite significant advances in our knowledge regarding the genetics and molecular biology of gliomas over the past two decades and hundreds of clinical trials, no effective therapeutic approach has been identified for adult patients with newly diagn
Externí odkaz:
https://doaj.org/article/29ca2523c543419b9c16450b3c0f82d3
Autor:
Dmitry S. Karpov, Anastasiia O. Sosnovtseva, Svetlana V. Pylina, Asya N. Bastrich, Darya A. Petrova, Maxim A. Kovalev, Anastasija I. Shuvalova, Anna K. Eremkina, Natalia G. Mokrysheva
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17320 (2023)
Type 1 diabetes mellitus (T1D) is an autoimmune disease caused by the destruction of insulin-producing β-cells in the pancreas by cytotoxic T-cells. To date, there are no drugs that can prevent the development of T1D. Insulin replacement therapy is
Externí odkaz:
https://doaj.org/article/7bf15955c004472190592c4a47af3b70
Autor:
Aleksei A. Stepanenko, Anastasiia O. Sosnovtseva, Marat P. Valikhov, Anastasia A. Chernysheva, Sergey A. Cherepanov, Gaukhar M. Yusubalieva, Zsolt Ruzsics, Anastasiia V. Lipatova, Vladimir P. Chekhonin
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 230-248 (2022)
Ad5-delta-24-RGD is currently the most clinically advanced recombinant adenovirus (rAd) for glioma therapy. We constructed a panel of fiber-modified rAds (Ad5RGD, Ad5/3, Ad5/35, Ad5/3RGD, and Ad5/35RGD, all harboring the delta-24 modification) and co
Externí odkaz:
https://doaj.org/article/6d4eb6490c95480e843e6653ecf13068
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Two-cycle cesium chloride (2 × CsCl) gradient ultracentrifugation is a conventional approach for purifying recombinant adenoviruses (rAds) for research purposes (gene therapy, vaccines, and oncolytic vectors). However, rAds containing the R
Externí odkaz:
https://doaj.org/article/10edaa59e24f4ba993cb64ff48bcec17
Autor:
Anastasiia O. Sosnovtseva, Olga V. Stepanova, Aleksei A. Stepanenko, Anastasia D. Voronova, Andrey V. Chadin, Marat P. Valikhov, Vladimir P. Chekhonin
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
The regeneration of nerve tissue after spinal cord injury is a complex and poorly understood process. Medication and surgery are not very effective treatments for patients with spinal cord injuries. Gene therapy is a popular approach for the treatmen
Externí odkaz:
https://doaj.org/article/18b905e47bee4ac4a5bc0b6fef1f9320
Autor:
Alexandra V. Panova, Natalia V. Klementieva, Anna V. Sycheva, Elena V. Korobko, Anastasia O. Sosnovtseva, Tatiana S. Krasnova, Maria R. Karpova, Petr M. Rubtsov, Yulia V. Tikhonovich, Anatoly N. Tiulpakov, Sergey L. Kiselev
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8824 (2022)
One of the causes of diabetes in infants is the defect of the insulin gene (INS). Gene mutations can lead to proinsulin misfolding, an increased endoplasmic reticulum (ER) stress and possible beta-cell apoptosis. In humans, the mechanisms underlying
Externí odkaz:
https://doaj.org/article/3471012972ef49dc980658f21544d4b8
Autor:
Victor A. Naumenko, Daniil A. Vishnevskiy, Aleksei A. Stepanenko, Anastasiia O. Sosnovtseva, Anastasiia A. Chernysheva, Tatiana O. Abakumova, Marat P. Valikhov, Anastasiia V. Lipatova, Maxim A. Abakumov, Vladimir P. Chekhonin
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1697 (2022)
Hepatotoxicity remains an as yet unsolved problem for adenovirus (Ad) cancer therapy. The toxic effects originate both from rapid Kupffer cell (KCs) death (early phase) and hepatocyte transduction (late phase). Several host factors and capsid compone
Externí odkaz:
https://doaj.org/article/cd8b4a03c98041d8bba2ce47cd6502ef
Autor:
A. D. Voronova, A. O. Sosnovtseva, O. V. Stepanova, A. V. Chadin, E. K. Karsuntseva, G. A. Fursa, I. V. Reshetov, V. P. Chekhonin
Publikováno v:
Bulletin of Experimental Biology and Medicine. 173:529-533
Autor:
E. K. Karsuntseva, G. A. Fursa, A. O. Sosnovtseva, A. D. Voronova, A. V. Chadin, A. S. Semkina, O. V. Stepanova, V. P. Chekhonin
Publikováno v:
Bulletin of Experimental Biology and Medicine. 172:617-621