Zobrazeno 1 - 10 of 230 pro vyhledávání: '"A. O. Salas"'
1
Akademický článek
Design, synthesis, cytotoxicity and 3D-QSAR analysis of new 3,6-disubstituted-1,2,4,5-tetrazine derivatives as potential antitumor agents
Autor: Álvaro Cañete-Molina, Christian Espinosa-Bustos, Marcos González-Castro, Mario Faúndez, Jaime Mella, Ricardo A. Tapia, Alan R. Cabrera, Iván Brito, Adam Aguirre, Cristian O. Salas
Publikováno v: Arabian Journal of Chemistry, Vol 12, Iss 7, Pp 1092-1107 (2019)
We synthesized two new series of 3-substituted-6-(2,5-dimethylpyrazol-1-yl)-1,2,4,5-tetrazines and analysed them for a potential role as antitumor agents. Twenty-two compounds were obtained, and four molecular structures were determined by X-ray diff
Externí odkaz: https://doaj.org/article/62245047d055465aa15eb2b1a71e58a5
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6
Akademický článek
A New Approach to the Synthesis of Benzo[b]naphtho[2,3-b]furan-6,11-diones and 2-Benzyl-3-hydroxynaphthalene-1,4-diones
Autor: Jose C. Barcia, Jacobo Cruces, Cristian O. Salas, Juan C. Estévez, Mauricio A. Cuellar, Ricardo A. Tapia, Ramón J. Estévez
Publikováno v: SynOpen, Vol 01, Iss 01, Pp 0156-0165 (2017)
Abstract Here we describe modified syntheses of o-acetylbenzoic acids­ and o-acetylphenylacetic acids by Heck palladium-catalysed aryl­ation of n-butyl vinyl ether with o-iodobenzoic acids or with o-iodo­phenylacetic acids, respectively. General s
Externí odkaz: https://doaj.org/article/70861953fe5f454ba750c90cba9d27e7
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7
Macular optical coherence tomography for screening of pathology prior to cataract surgery: An approach based on tele-evaluation
Autor: A. Herranz-Cabarcos, Z. Vega-López, O. Salas-Fandos, MJ Quiroz-Quiroga, P. Burgos-Fernández, P. Martí-Rodrigo, M. Castilla-Marti, V. Poposki, AR. Martínez-Palmer
Publikováno v: European Journal of Ophthalmology. 32:3433-3437
Background To assess the benefit of macular spectral-domain optical coherence tomography (SD-OCT) as a part of the routinary preoperative study of patients undergoing cataract surgery. Methods A prospective single-center study study was performed. Co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9805f5691b94983f40d09a61eaabb7b
https://doi.org/10.1177/11206721221080818
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8
Expanding the chemical space of aryloxy-naphthoquinones as potential anti-Chagasic agents: synthesis and trypanosomicidal activity
Autor: Sofía Toledo, Jorge Cantero, Christian Espinosa-Bustos, Benjamín Nogueda, Cristian O. Salas, Uziel Castillo-Velázquez, Fabiola Chacón-Vargas, Margot Paulino, Ana F. Elizondo Rodríguez, Adriana Moreno-Rodríguez, Mario Aranda, Gildardo Rivera, Karina Vázquez, Nohemí A. Becerra
Publikováno v: Medicinal Chemistry Research. 30:2256-2265
In continuation our effort to research the chemical space of aryloxy-naphthoquinones as potential anti-Chagas agents, we synthesized nine derivatives and these compounds were evaluated in vitro against the epimastigote and trypomastigote forms of Mex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94b2f14c8d0f23a54acbfc529310ea1
https://doi.org/10.1007/s00044-021-02809-3
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10
Akademický článek
Synthesis and Pharmacophore Modelling of 2,6,9-Trisubstituted Purine Derivatives and Their Potential Role as Apoptosis-Inducing Agents in Cancer Cell Lines
Autor: Jeannette Calderón-Arancibia, Christian Espinosa-Bustos, Álvaro Cañete-Molina, Ricardo A. Tapia, Mario Faúndez, Maria Jose Torres, Adam Aguirre, Margot Paulino, Cristian O. Salas
Publikováno v: Molecules, Vol 20, Iss 4, Pp 6808-6826 (2015)
A series of 2,6,9-trisubstituted purine derivatives have been synthesized and investigated for their potential role as antitumor agents. Twelve compounds were obtained by a three step synthetic procedure using microwave irradiation in a pivotal step.
Externí odkaz: https://doaj.org/article/6ec0ca89f7dc4102b40e113219296dba
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