Zobrazeno 1 - 10
of 13
pro vyhledávání: '"A. O. Cezairliyan"'
Autor:
Javier E Irazoqui, Emily R Troemel, Rhonda L Feinbaum, Lyly G Luhachack, Brent O Cezairliyan, Frederick M Ausubel
Publikováno v:
PLoS Pathogens, Vol 6, p e1000982 (2010)
The genetically tractable model host Caenorhabditis elegans provides a valuable tool to dissect host-microbe interactions in vivo. Pseudomonas aeruginosa and Staphylococcus aureus utilize virulence factors involved in human disease to infect and kill
Externí odkaz:
https://doaj.org/article/76c0033378534fd5850f02fdbc4027f2
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Pathogenic bacteria secrete toxins and degradative enzymes that facilitate their growth by liberating nutrients from the environment. To understand bacterial growth under nutrient-limited conditions, we studied resource allocation between cellular an
Autor:
Nidhi Ahuja, Robert T. Sauer, Brent O. Cezairliyan, Carol A. Gross, Kyeong Kyu Kim, Rachna Chaba, Dmitry Korkin
Publikováno v:
Journal of Biological Chemistry. 284:5403-5413
The Escherichia coli envelope stress response is controlled by the alternative sigma factor, σE, and is induced when unfolded outer membrane proteins accumulate in the periplasm. The response is initiated by sequential cleavage of the membrane-spann
Autor:
Brent O. Cezairliyan, Robert T. Sauer
Publikováno v:
Proceedings of the National Academy of Sciences. 104:3771-3776
The Escherichia coli envelope-stress response is a sensor system that increases transcription of stress genes in the cytoplasm when misfolded porins are detected in the periplasm. This response is initiated by DegS cleavage of the periplasmic domain
Publikováno v:
Proceedings of the National Academy of Sciences. 102:2305-2309
We designed a single-chain variant of the Arc repressor homodimer in which the β strands that contact operator DNA are connected by a hairpin turn and the α helices that form the tetrahelical scaffold of the dimer are attached by a short linker. Th
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1149
The nematode Caenorhabditis elegans is a simple model host for studying the interaction between bacterial pathogens such as Pseudomonas aeruginosa and the metazoan innate immune system. Powerful genetic and molecular tools in both C. elegans and P. a
Publikováno v:
Methods in Molecular Biology ISBN: 9781493904723
The nematode Caenorhabditis elegans is a simple model host for studying the interaction between bacterial pathogens such as Pseudomonas aeruginosa and the metazoan innate immune system. Powerful genetic and molecular tools in both C. elegans and P. a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8ed5ce9a1ead234033d09019e059805
https://doi.org/10.1007/978-1-4939-0473-0_50
https://doi.org/10.1007/978-1-4939-0473-0_50
Publikováno v:
Gene. 261:115-125
The neutralist-selectionist debate should not be viewed as a dichotomy but as a continuum. While the strictly neutral model suggests a neutralist-selectionist dichotomy, the nearly neutral model is a continuous model spanning strict neutrality throug
Autor:
Frederick M. Ausubel, Daniel Grenfell-Lee, Alan Saghatelian, Nawaporn Vinayavekhin, Brent O. Cezairliyan, Grace J. Yuen
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003101 (2013)
PLoS Pathogens
PLoS Pathogens
Pathogenic microbes employ a variety of methods to overcome host defenses, including the production and dispersal of molecules that are toxic to their hosts. Pseudomonas aeruginosa, a Gram-negative bacterium, is a pathogen of a diverse variety of hos
Autor:
Brent O. Cezairliyan, Robert T. Sauer
Publikováno v:
Molecular microbiology. 72(2)
The ability of a pathogen to survive the defensive attacks of its host requires the detection of and response to perturbations in its own physiology. Activation of the extracytoplasmic stress response in the pathogen Pseudomonas aeruginosa results in