Zobrazeno 1 - 10
of 167
pro vyhledávání: '"A. Nuhrich"'
Autor:
Beuchet, Pierre, Varache-Lembège, Martine, Neveu, Arlette, Léger, Jean-Michel, Vercauteren, Joseph, Larrouture, Stéphane, Deffieux, Gérard, Nuhrich, Alain *
Publikováno v:
In European Journal of Medicinal Chemistry 1999 34(9):773-779
Autor:
Lacan, Fabrice, Varache-Lembège, Martine, Vercauteren, Joseph, Léger, Jean-Michel, Masereel, Bernard, Dogné, Jean-Michel, Nuhrich, Alain *
Publikováno v:
In European Journal of Medicinal Chemistry 1999 34(4):311-328
Autor:
A. Nuhrich, Djibril Fall, Stéphane Larrouture, Stéphane Moreau, Joseph Vercauteren, Gérard Deffieux, Martine Varache-Lembège, Arlette Neveu
Publikováno v:
European Journal of Medicinal Chemistry. 37:237-253
A series of arylhydrazones derived from various 6,8-diacetoxy- or 6,8-dihydroxy-9-oxo-9H-xanthene carboxaldehydes were synthesized and evaluated for their in vitro antifungal properties against two human pathogenic yeasts (Candida albicans and C. kru
Autor:
Jean-François Peyrat, Gérard Deffieux, A. Nuhrich, Joseph Vercauteren, Bastien Nay, Valérie Arnaudinaud, Jean-Michel Mérillon
Publikováno v:
European Journal of Organic Chemistry. 2000:1279-1283
Racemic 4-[13C]catechin 14 has been synthesized in ten steps starting from potassium [13C]cyanide. The intermediate chalcone 9 was formed by acylation of the benzylated phloroglucinol 7 with the caffeic acid synthon 6, using the trifluoroacetic mixed
Autor:
Stephane Larrouture, Jean-Michel Léger, Arlette Neveu, Gérard Deffieux, Pierre Beuchet, Martine Varache-Lembège, A. Nuhrich, Joseph Vercauteren
Publikováno v:
European Journal of Medicinal Chemistry. 34:773-779
Polymethoxylated and polyhydroxylated derivatives of 2-amino-4-arylthiazoles bearing a halogenobenzenesulfonamide moiety at position 2 were synthesized as azole antifungal analogues. X-ray crystallography studies revealed the predominance of the 2-im
Autor:
F. Lacan, Bernard Masereel, Jacques Damas, Jacques Delarge, Jean-Michel Dogné, Jeanine Fontaine, A. Nuhrich, Lionel Pochet, Martine Lembege
Publikováno v:
University of Namur
Torasemide, a loop diuretic, has been reported to relax dog coronary artery precontracted by thromboxane A2 (TXA2), an endogenous prostanoid involved in cardiovascular and pulmonary diseases. N-cyano-N′-{[4-(3′-methylphenylamino)pyrid-3-yl]sulpho
Tautomerism in a 2,4-dichlorobenzenesulfonamide derived from 2-amino-4-(2,5-dimethoxyphenyl)thiazole
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 55:791-794
2,4-Dichloro-N-[2,3-dihydro-4-(2,5-dimethoxyphenyl)thiazol-2-ylidene]benzenesulfonamide, C 17 H 14 Cl 2 N 2 O 4 S 2 , crystallizes in space group P1 with two independent molecules. The structural parameters do not indicate a tautomeric equilibrium bu
Autor:
Jean-Michel Léger, A. Nuhrich, Joseph Vercauteren, Martine Varache-Lembège, Jean-Michel Dogné, F. Lacan, Bernard Masereel
Publikováno v:
European Journal of Medicinal Chemistry. 34:311-328
A series of new 2-[(arylsulfonyl)imino]-2,3-dihydrothiazolyl derivatives substituted on the heterocyclic N by a phenoxyacetic moiety was prepared according to a Hantzsch's synthesis between N, N'-disubstituted thioureas and chloroacetaldehyde. The re
Autor:
Anne-Marie Vacher, V Zemb, G. Devaux, Pierre Vacher, A. Nuhrich, Martine Varache-Lembège, Bernard Dufy
Publikováno v:
European Journal of Medicinal Chemistry. 31:547-556
Summary The synthesis of a thienyl dihydropyridine series according to the Hantzsch method is described. The influence of these derivatives on intracellular calcium ([Ca + ]) in GH3 cells was evaluated in vitro using spectrofluorimetry with indol as
Publikováno v:
European Journal of Medicinal Chemistry. 31:957-964
Summary A series of 1,2-benzisoxazole-3-carboxamides derived from tertiary cycloalkylamines was synthesized and evaluated for affinity for serotonergic (5-HT 3 and 5-HT 4 ) and dopaminergic (D 2 ) receptors using radioligand binding assays. The major