Zobrazeno 1 - 10
of 21
pro vyhledávání: '"A. Nicole Desch"'
Autor:
Manuel A. Rivas, Daniel Graham, Patrick Sulem, Christine Stevens, A. Nicole Desch, Philippe Goyette, Daniel Gudbjartsson, Ingileif Jonsdottir, Unnur Thorsteinsdottir, Frauke Degenhardt, Sören Mucha, Mitja I. Kurki, Dalin Li, Mauro D’Amato, Vito Annese, Severine Vermeire, Rinse K. Weersma, Jonas Halfvarson, Paulina Paavola-Sakki, Maarit Lappalainen, Monkol Lek, Beryl Cummings, Taru Tukiainen, Talin Haritunians, Leena Halme, Lotta L. E. Koskinen, Ashwin N. Ananthakrishnan, Yang Luo, Graham A. Heap, Marijn C. Visschedijk, UK IBD Genetics Consortium, NIDDK IBD Genetics Consortium, Daniel G. MacArthur, Benjamin M. Neale, Tariq Ahmad, Carl A. Anderson, Steven R. Brant, Richard H. Duerr, Mark S. Silverberg, Judy H Cho, Aarno Palotie, Päivi Saavalainen, Kimmo Kontula, Martti Färkkilä, Dermot P. B. McGovern, Andre Franke, Kari Stefansson, John D. Rioux, Ramnik J. Xavier, Mark J. Daly
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
While hundreds of loci are linked with inflammatory bowel diseases (IBDs), the functional consequences of the associated variants remain unclear. Here, the authors screened in ulcerative colitis (UC) patients’ genomes for protein-truncating variant
Externí odkaz:
https://doaj.org/article/7ec515461747449295bc0f9f7b59f420
Autor:
Manuel A. Rivas, Daniel Graham, Patrick Sulem, Christine Stevens, A. Nicole Desch, Philippe Goyette, Daniel Gudbjartsson, Ingileif Jonsdottir, Unnur Thorsteinsdottir, Frauke Degenhardt, Sören Mucha, Mitja I. Kurki, Dalin Li, Mauro D’Amato, Vito Annese, Severine Vermeire, Rinse K. Weersma, Jonas Halfvarson, Paulina Paavola-Sakki, Maarit Lappalainen, Monkol Lek, Beryl Cummings, Taru Tukiainen, Talin Haritunians, Leena Halme, Lotta L. E. Koskinen, Ashwin N. Ananthakrishnan, Yang Luo, Graham A. Heap, Marijn C. Visschedijk, UK IBD Genetics Consortium, NIDDK IBD Genetics Consortium, Daniel G. MacArthur, Benjamin M. Neale, Tariq Ahmad, Carl A. Anderson, Steven R. Brant, Richard H. Duerr, Mark S. Silverberg, Judy H. Cho, Aarno Palotie, Päivi Saavalainen, Kimmo Kontula, Martti Färkkilä, Dermot P. B. McGovern, Andre Franke, Kari Stefansson, John D. Rioux, Ramnik J. Xavier, Mark J. Daly
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)
Nature Communications 7 Article number: 12342 (2016); Published 9 August 2016; Updated 13 September 2016 The HTML version of this Article incorrectly listed the authors of the UK IBD Genetics Consortium and the NIDDK IBD Genetics Consortium individua
Externí odkaz:
https://doaj.org/article/750183ef44f04abe937a2d55611517af
Autor:
Hannah Marienberg, Nicole Desch, Vitalii Mozin, Lorenz Sykora‐Mirle, Anja Müller, Andreas Roth, Mathias Käfer, Rüdiger Neef
Publikováno v:
Engineering in Life Sciences, Vol 24, Iss 3, Pp n/a-n/a (2024)
Abstract Process Analytical Technologies (PATs) are taking a key role in the run for automatization in the biopharmaceutical industry. Spectroscopic methods such as Raman spectroscopy or mid‐infrared (MIR) spectroscopy are getting more recognition
Externí odkaz:
https://doaj.org/article/d7ed826a912e449dbf4d6fce2bc19ebd
Autor:
Victor H. Engelhard, Craig L. Slingluff, Mark Conaway, Donna H. Deacon, Kara L. Cummings, Joel Pinczewski, A. Nicole Desch, Rebecca C. Obeng, Angela L. Zarling
Supplemental Figure 1. Sequence of pIRS-21097-1105 TCR chains. Supplemental Figure 2. Sequence of pCDC25b38-46 TCR chains. Supplemental Figure 3. Electroporation of IVT RNA encoding murine TCR chains results in functional cell surface expression of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487c7ebd428a56baf90a2dda7f5c4ffb
https://doi.org/10.1158/0008-5472.22403447
https://doi.org/10.1158/0008-5472.22403447
Autor:
Eider Valle-Encinas, Roshni Nair, Katerina Pisa, Mayke Doorn, Farzin Pourfarzad, Lani San Mateo, Nicole Desch, Prashanth Gokare, David Pocalyko, Sylvia F. Boj, Carla Verissimo
Publikováno v:
Cancer Research. 83:5917-5917
Pathogens such as colibactin-producing bacteria strains of the Enterobacteriaceae family are highly prevalent in the gut microbiota of colorectal cancer (CRC) patients. HUB patient derived Organoids, (HUB-OrganoidsTM or PDOs) are self-organized epith
Autor:
Steven A. Carr, Elizabeth A. Creasey, A. Nicole Desch, Atul K. Bhan, Zhifang Cao, Vishnu Mohanan, Gaelen Guzman, Chloé Lévesque, Junmei Yao, Angela C. Boroughs, Monica Schenone, Ramnik J. Xavier, Toru Nakata, John D. Rioux, Guy Charron, Kara G. Lassen, Gabrielle Boucher, Hans Christian Reinecker, Mark J. Daly
Publikováno v:
Science. 359:1161-1166
Overcoming a barrier to IBD Inflammatory bowel disease (IBD) is a group of disorders linked to inflammation of the gastrointestinal tract. Colitis is a type of IBD that affects the inner lining of the colon and has been linked to a gene known as C1or
Autor:
Patrick Deelen, Niek de Klein, Cisca Wijmenga, Mark J. Daly, Christine P. Petersen, Mukund Varma, A. Nicole Desch, Ramnik J. Xavier, Steven A. Carr, Gaelen Guzman, Aylwin Ng, Daniel B. Graham, Atul K. Bhan, Angela C. Boroughs, Ariel Lefkovith, Manuel A. Rivas, Monica Schenone
Publikováno v:
Elsevier
Cell reports, 17(11), 2955-2965. CELL PRESS
Cell reports, 17(11), 2955-2965. CELL PRESS
Summary - Significant insights into disease pathogenesis have been gleaned from population-level genetic studies; however, many loci associated with complex genetic disease contain numerous genes, and phenotypic associations cannot be assigned unequi
Autor:
Sonia M. Leach, Miglena Prabagar, William J. Janssen, Sophie L. Gibbings, A. Nicole Desch, Rajni Goyal, Shaikh M. Atif, Claudia Jakubzick, Donna L. Bratton
Publikováno v:
Blood. 126:1357-1366
Alveolar macrophages (AMs) reside on the luminal surfaces of the airways and alveoli where they maintain host defense and promote alveolar homeostasis by ingesting inhaled particulates and regulating inflammatory responses. Recent studies have demons
Autor:
Ronald G. Gill, Peter M. Henson, Ross M. Kedl, Todd J. Grazia, Philippa Marrack, Claudia Jakubzick, A. Nicole Desch, Shaikh M. Atif, Sophie L. Gibbings, Michelle K. Nelsen, Kenneth M. Murphy
Publikováno v:
The Journal of Immunology. 195:46-50
In transplantation, a major obstacle for graft acceptance in MHC-matched individuals is the mismatch of minor histocompatibility Ags. Minor histocompatibility Ags are peptides derived from polymorphic proteins that can be presented by APCs on MHC mol
Autor:
Donna L. Bratton, Sonia M. Leach, Sophie L. Gibbings, Stacey M. Thomas, A. Nicole Desch, Peter M. Henson, Shaikh M. Atif, Alexandra L. McCubbrey, William J. Janssen, Claudia Jakubzick, Thomas Danhorn
Publikováno v:
American journal of respiratory cell and molecular biology. 57(1)
The current paradigm in macrophage biology is that some tissues mainly contain macrophages from embryonic origin, such as microglia in the brain, whereas other tissues contain postnatal-derived macrophages, such as the gut. However, in the lung and i