Zobrazeno 1 - 10
of 38
pro vyhledávání: '"A. N. Silkov"'
Autor:
K. V. Nazarov, R. Yu. Perik-Zavodsky, M. S. Kuznetsova, Yu. G. Philippova, Yu. A. Shevchenko, V. V. Denisova, A. N. Silkov, S. V. Sennikov
Publikováno v:
Acta Biomedica Scientifica, Vol 7, Iss 5-1, Pp 179-187 (2022)
Introduction. Bone marrow erythroblasts produce a wide range of cytokines with opposite biological effects. This may be due to a change in the spectrum of production of immunoregulatory mediators during differentiation and small qualitative and quant
Externí odkaz:
https://doaj.org/article/09db14e5ce904e3595ef437c406202e2
Autor:
A. S. Bulygin, V. P. Tereshchenko, R. Yu. Zavodskii, I. A. Obleukhova, S. V. Sennikov, A. N. Silkov
Publikováno v:
Медицинская иммунология, Vol 23, Iss 4, Pp 653-658 (2021)
Today transfection of mammalian cell with DNA or RNA construction is the only method for delivering programmed information into the cell nucleus. Electroporation is most commonly used method of transfection in experiments with dendritic cell. The aim
Externí odkaz:
https://doaj.org/article/8c5f64c187004a1aad527da9c86e420e
Autor:
Yu. V. Zhukova, A. A. Alshevskaya, F. D. Kireev, O. A. Chumasova, N. S. Shkaruba, A. E. Sizikov, Yu. A. Lopatnikova, D. V. Demina, A. V. Karaulov, A. N. Silkov, S. V. Sennikov
Publikováno v:
Медицинская иммунология, Vol 23, Iss 4, Pp 903-908 (2021)
A pleiotropic cytokine TNFα is an important inflammatory mediator of a number of diseases; its biological functions are fulfilled through two different receptors, TNFR1 and TNFR2. Changes in the ratio between these types of receptors shifting the ba
Externí odkaz:
https://doaj.org/article/482fd1a256c14ef8b21598e321ea6907
Autor:
M. S. Kuznetsova, J. A. Shevchenko, J. N. Khantakova, A. A. Khristin, I. A. Obleukhova, A. N. Silkov, S. V. Sidorov, S. V. Sennikov
Publikováno v:
Медицинская иммунология, Vol 23, Iss 4, Pp 785-790 (2021)
The NF-κB transcription factor controls the expression of genes responsible for cell cycle, apoptosis, and other immunoregulatory functions. Some nonspecific NF-κB inhibitors were found after discovering the possibility of blocking tumor growth thr
Externí odkaz:
https://doaj.org/article/665db60d517d4864b608bc5c4ed8e1ce
Publikováno v:
Медицинская иммунология, Vol 19, Iss 2, Pp 185-190 (2017)
Search for molecular genetic markers of risk and prognosis of breast cancer is an important prospective of modern research. Many molecular mechanisms are involved in pathogenesis of breast cancer and define a wide range of possible candidate genes. T
Externí odkaz:
https://doaj.org/article/98012831a853408aa1aacb0b0a16eb9d
Autor:
A. N. Silkov, N. S. Shkaruba, T. A. Kalashnikova, L. P. Sizyakina, J. B. Shulman, S. V. Dolgikh, V. I. Mazurov, O. A. Gerzog, A. E. Sizikov, V. A. Kozlov, S. V. Sennikov
Publikováno v:
Медицинская иммунология, Vol 14, Iss 1-2, Pp 81-86 (2014)
Abstract. Prevalence of TNFα gene promoter polymorphism at -857 position was investigated in normal persons and among patients with rheumatoid arthritis. We detected a relation of this polymorphism to the levels of TNFα production by mononuclear ce
Externí odkaz:
https://doaj.org/article/95b6b45dc0704e0f90fa95372ca01f96
Autor:
N. S. Shkaruba, P. P. Vasiliev, A. N. Silkov, J. A. Sennikova, J. A. Lopatnikova, A. E. Sizikov, T. A. Kalashnikova, L. P. Sizyakina, J. B. Shulman, S. V. Dolgikh, V. I. Mazurov, S. V. Sennikov
Publikováno v:
Acta Biomedica Scientifica, Vol 0, Iss 3(2), Pp 237-240 (2012)
In this paper we studied the frequency of allelic variants of genes TNFRI at positions -609 and -1207 and TNFRII at positions -1709 and -3609 in patients with rheumatoid arthritis and in population control group. It was shown that the resulting frequ
Externí odkaz:
https://doaj.org/article/7a47c71f93ac4520b854d1fbedf2eafd
Autor:
A. N. Silkov, T. V. Kovalevskaya-Kutcheryavenko, S. A. Falaleyeva, J. A. Shevchenko, V. M. Nepomnyaschikh, S. V. Sennikov
Publikováno v:
Acta Biomedica Scientifica, Vol 0, Iss 3(2), Pp 175-179 (2012)
The рарег presents the results of measurements of cytokine levels in serum and conditioned medium of PBMC cultures from the patients with atopic dermatitis with the exacerbation and remission in comparison with the healthy donors. We have shown
Externí odkaz:
https://doaj.org/article/9cca6afde04042d88385257bad827212
Publikováno v:
Бюллетень сибирской медицины, Vol 9, Iss 3, Pp 51-56 (2010)
Alternatively spliced interleukins are very actively studied over the last years. Splice form of IL-4 — IL-4δ2 has antagonistic effects to its full form on proliferative activity of human mononuclear blood cells and their IL-6 production. Antagoni
Externí odkaz:
https://doaj.org/article/223670efa9e04cc9b272c4f0fbdf969b
Autor:
I. A. Obleukhova, J. A. Shevchenko, S V Sidorov, Sergey V. Sennikov, A. A. Khristin, J. N. Khantakova, M. S. Kuznetsova, A. N. Silkov
Publikováno v:
Medicinskaâ Immunologiâ, Vol 23, Iss 4, Pp 785-790 (2021)
The NF-κB transcription factor controls the expression of genes responsible for cell cycle, apoptosis, and other immunoregulatory functions. Some nonspecific NF-κB inhibitors were found after discovering the possibility of blocking tumor growth thr