Výsledky vyhledávání - "A. N. Saprin"

Involvement of thio-, peroxi-, and glutaredoxins in cellular redox-dependent processes

Autor: Elena Kalinina, A. N. Saprin, N. N. Chernov

Publikováno v: Biochemistry (Moscow). 73:1493-1510

Among the key antioxidant enzymes, thioredoxin and glutaredoxin systems play an important role in cell defense against oxidative stress and maintenance of redox homeostasis owing to the regulation of thiol-disulfide exchange. The thioredoxin isoforms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61476d4f607b51edf27189f462b3b971
https://doi.org/10.1134/s0006297908130099

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Changes in expression of genes encoding antioxidant enzymes, heme oxygenase-1, Bcl-2, and Bcl-xl and in level of reactive oxygen species in tumor cells resistant to doxorubicin

Autor: N. N. Chernov, Elena Kalinina, Ya. N. Kotova, N. P. Scherbak, V. S. Solomka, A. N. Saprin, Ya. A. Andreev

Publikováno v: Biochemistry (Moscow). 71:1200-1206

The relationship between expression of genes encoding key antioxidant enzymes, heme oxygenase-1, Bcl-2, and Bcl-xl and change in production of reactive oxygen species (ROS) resulting from development of resistance of cancer cells K562, MCF-7, and SKO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e138dab1b6dee0082e624918508245
https://doi.org/10.1134/s0006297906110058

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Changes in the free-radical state and the level of free iron during the development of drug resistance in tumor cells

Autor: V. S. Solomka, N. P. Shcherbak, Elena Kalinina, Ya. N. Kotova, A. N. Saprin, V. A. Serezhenkov

Publikováno v: Biophysics. 51:435-439

The free-radical state of K562 human erythroleukemia cells changes during the development of resistance to doxorubicin, an antitumor antibiotic with prooxidant action widely used in oncology. It was found that the level of superoxide anion in the res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0bdad94b8364aed484500e4d0ed6478e
https://doi.org/10.1134/s0006350906030158

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Pharmacogenetic Problems of Antitumor Therapy (A Review)

Autor: V. A. Sukhanov, L. A. Piruzyan, A. N. Saprin

Publikováno v: Pharmaceutical Chemistry Journal. 38:347-354

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::165592049d7d3326513a94cd769cdded
https://doi.org/10.1023/b:phac.0000048430.49990.0b

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The Role of the Metabolic Status of the Donor and the Recipient in Survival of a Skin Graft according to Histological Data

Autor: E K Gasanov, Piruzian La, A. N. Saprin, V I Shumakov, V T Vasilenko, V. A. Sukhanov

Publikováno v: Human Physiology. 30:435-440

The role of the metabolic status of the donor and the recipient in graft survival was studied with skin grafting between genetically different mouse strains (BALB/C, C3HA, DBA/2, and C57Bl/6). It was concluded that the donor must have a lower metabol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e5c5e545d75c8f7290f4a385ac2c54b
https://doi.org/10.1023/b:hump.0000036338.81657.ca

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[Untitled]

Autor: L. A. Piruzyan, A. N. Saprin, T. Yu. Fedorova, V. A. Sukhanov, E. V. Kalinina

Publikováno v: Biology Bulletin of the Russian Academy of Sciences. 29:115-119

We studied intraspecific features of the main enzymes of metabolism and detoxication of xenobiotics on mice (eight inbred lines) and rats (five lines) for estimation of possible variants of complete or incomplete metabolic equality. Significant genet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0979cc89d82b5aaf4dd3e7aae6e4d65f
https://doi.org/10.1023/a:1014346730648

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Prognostic risk factor of the development of pathological processes based on polymorphism of xenobiotic metabolism enzymes

Autor: V. A. Sukhanov, A. N. Saprin, L. A. Piruzyan

Publikováno v: Human Physiology. 26:224-231

Analysis of the literature concerning the possibilities of predicting the risk of the development of pathological processes based on the polymorphism of the enzymes of metabolism and detoxification of xenobiotics (EMDX)—cytochrome P-450, glutathion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3bafb7ae58ac556833b23a92dfa50c2a
https://doi.org/10.1007/bf02760097

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[Untitled]

Autor: V I Shumakov, V T Vasilenko, L. A. Piruzyan, V. A. Sukhanov, E K Gasanov, A. N. Saprin

Publikováno v: Doklady Biological Sciences. 388:35-37

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4823b9d75bc5387f6161da306c43b87
https://doi.org/10.1023/a:1022491725536

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[Untitled]

Autor: A. N. Saprin, L. A. Piruzyan, E. V. Kalinina, V. A. Sukhanov

Publikováno v: Doklady Biochemistry and Biophysics. 377:72-74

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b41d622271ba14a565a098753b93a6b7
https://doi.org/10.1023/a:1011567304333

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[Current views on antioxidative activity of glutathione and glutathione-depending enzymes]

Autor: E V, Kalinina, N N, Chernov, R, Aleud, M D, Novichkova, A N, Saprin, T T, Berezov

Publikováno v: Vestnik Rossiiskoi akademii meditsinskikh nauk. (3)

Reduced glutathione (GSH), gamma-glutamyl-L-cysteineglycine, is a tripeptide widespread in plants, animals, and man as a low-molecular weight SH-containing compound. This review presents results of published and original studies concerned with the sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d60d10995ecd2a6036a5719e2be91bc2
https://pubmed.ncbi.nlm.nih.gov/20420216

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