Zobrazeno 1 - 10
of 33
pro vyhledávání: '"A. N. Mayeno"'
Publikováno v:
Environmental Science & Technology. 52:9845-9850
The permanganate ion (MnO4–) has been widely used as a reagent for water treatment for over a century. It is a strong enough oxidant to activate carbon–hydrogen bonds, one of the most important reactions in biological and chemical systems. Our cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435292ca465897f16411df9ad98207ec
https://doi.org/10.1021/acs.est.8b03157
https://doi.org/10.1021/acs.est.8b03157
Autor:
Michael A. Lyons, Elizabeth J. Brooks, C. P. Metzler, Mary Ann DeGroote, Arthur N. Mayeno, Brad Reisfeld
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:926-934
The emergence of multidrug-resistant tuberculosis (MDR-TB) has led to a renewed interest in the use of second-line antibiotic agents. Unfortunately, there are currently dearths of information, data, and computational models that can be used to help d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad84f9a7ea97df83cad44cf54b54185c
https://doi.org/10.1128/aac.05180-11
https://doi.org/10.1128/aac.05180-11
Publikováno v:
Journal of Computational Chemistry. 32:639-657
Cytochrome P450 (CYP) enzymes play a critical role in detoxication and bioactivation of xenobiotics; thus, the ability to predict the biotransformation rates and regioselectivity of CYP enzymes toward substrates is an important goal in toxicology and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755d8b18a09f4838548f0830207fc34d
https://doi.org/10.1002/jcc.21649
https://doi.org/10.1002/jcc.21649
Publikováno v:
Principles and Practice of Mixtures Toxicology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f9f9ce0a44b40d2ce3efd75fe89a496
https://doi.org/10.1002/9783527630196.ch22
https://doi.org/10.1002/9783527630196.ch22
Publikováno v:
Environmental Health Perspectives
Background One problem of interpreting population-based biomonitoring data is the reconstruction of corresponding external exposure in cases where no such data are available. Objectives We demonstrate the use of a computational framework that integra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e324daed5a48e7a7c03c0544533978d4
https://doi.org/10.1289/ehp.11079
https://doi.org/10.1289/ehp.11079
Publikováno v:
Drug Metabolism Reviews. 40:1-100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::892582306dd1f08964d096a5b2d77a6b
https://doi.org/10.1080/03602530701836662
https://doi.org/10.1080/03602530701836662
Publikováno v:
Drug Metabolism Reviews. 40:1-288
Cytochromes P450 (CYPs) are a superfamily of enzymes that metabolize the majority of xenobiotics in humans. This review presents a structure-based outline of CYP-catalyzed biotransformations of selected substrates, representing diverse structural cla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa02054318a2107a1371111aaf288dda
https://doi.org/10.1080/03602530802309742
https://doi.org/10.1080/03602530802309742
Publikováno v:
Journal of Chromatography B. 824:166-174
A novel and sensitive high-performance liquid chromatography (HPLC) method was developed to analyze dione metabolites of benzo[a]pyrene (BaP). Because BaP-diones do not fluoresce, detection of low concentrations is difficult to achieve when analyzing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3fc1fe576dba07b4c562adf013ac2fc
https://doi.org/10.1016/j.jchromb.2005.07.021
https://doi.org/10.1016/j.jchromb.2005.07.021
Publikováno v:
Environmental Science & Technology. 39:5363-5371
All organisms are exposed to multiple xenobiotics, through food, environmental contamination, and drugs. These xenobiotics often undergo biotransformation, a complex process that plays a critical role in xenobiotic elimination or bioactivation to tox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa311bc343568d2de0aa800ecb452b62
https://doi.org/10.1021/es0479991
https://doi.org/10.1021/es0479991
Autor:
Sanjiv Sur, Arthur N. Mayeno, Tsukasa Ohnishi, Gerald J. Gleich, Shinji Okada, David H. Broide, H. Kita
Publikováno v:
Clinical and Experimental Immunology. 104:325-331
SUMMARY Eosinophils and eosinophil granule proteins may play an important role in the pathogenesis of asthma. BALF from 40 patients with symptomatic asthma were analysed for cytokine activity by the eosinophil survival assay. BALF from 15 patients sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70119820c3683e395caaa500aed6379b
https://doi.org/10.1046/j.1365-2249.1996.32737.x
https://doi.org/10.1046/j.1365-2249.1996.32737.x