Zobrazeno 1 - 10
of 125
pro vyhledávání: '"A. N. Keane"'
Autor:
R McAvera, I Drozdz, H Black, T Cichocka, E Szegezdi, J Quinn, P Murphy, P Thornton, M Perera, R Clifford, N Keane, V Mykytiv, E Elhassadi, R Cummins, M O’Dwyer, S Glavey
Publikováno v:
HemaSphere, Vol 7, Iss S2, Pp 9-10 (2023)
Externí odkaz:
https://doaj.org/article/47cba3df986d4698bef7afba9791e388
Autor:
Emily K. Calton, Kevin N. Keane, Raquel Raizel, Jordan Rowlands, Mario J. Soares, Philip Newsholme
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 814-820 (2017)
Background: Vitamin D status [25(OH)D] has recently been reported to be associated with altered cellular bioenergetic profiles of peripheral blood mononuclear cells (PBMCs). No study has tracked the seasonal variation of 25(OH)D and its putative infl
Externí odkaz:
https://doaj.org/article/e7be4ad5fb884680b5f134d7600c9298
Autor:
Rodrigo Carlessi, Younan Chen, Jordan Rowlands, Vinicius F. Cruzat, Kevin N. Keane, Lauren Egan, Cyril Mamotte, Rebecca Stokes, Jenny E. Gunton, Paulo Ivo Homem de Bittencourt, Philip Newsholme
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Glucagon-like peptide-1 (GLP-1) promotes insulin secretion from pancreatic β-cells in a glucose dependent manner. Several pathways mediate this action by rapid, kinase phosphorylation-dependent, but gene expression-independent mechanisms. S
Externí odkaz:
https://doaj.org/article/caf5cdca187a473db8fc37928e03d4c9
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
The role of growth hormone (GH) in human fertility is widely debated with some studies demonstrating improvements in oocyte yield, enhanced embryo quality, and in some cases increased live births with concomitant decreases in miscarriage rates. Howev
Externí odkaz:
https://doaj.org/article/1a0fb023a77f446080f9ff0fa9c042ff
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
The current understanding of human growth hormone (hGH; here GH) action is that the molecule is a 191-amino acid, single-chain polypeptide that is synthesized, stored and secreted by the somatotroph cells within the lateral wings of the anterior pitu
Externí odkaz:
https://doaj.org/article/99f67e206648484388013a0634761e06
Publikováno v:
Redox Biology, Vol 10, Iss C, Pp 243-250 (2016)
Background: Circulating peripheral blood mononuclear cells (PBMCs) are exposed to metabolic and immunological stimuli that influence their functionality. We hypothesized that prevailing vitamin D status [25(OH)D] would modulate the bioenergetic profi
Externí odkaz:
https://doaj.org/article/63ccef25cd6446fabd67d8b60d6d510a
Autor:
Kevin N. Keane, Peter M. Hinchliffe, Philip K. Rowlands, Gayatri Borude, Shanti Srinivasan, Satvinder S. Dhaliwal, John L. Yovich
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
BackgroundIn vitro fertilization (IVF) patients receive various adjuvant therapies to enhance success rates, but the true benefit is actively debated. Growth hormone (GH) and dehydroepiandrosterone (DHEA) supplementation were assessed in women underg
Externí odkaz:
https://doaj.org/article/31a4e9fcb2e64fd194cca19d59cf8735
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141770 (2015)
Chronic low-grade inflammation accompanies obesity and its related chronic conditions. Both peripheral blood mononuclear cells (PBMCs) and cell lines have been used to study whether vitamin D has immune modulating effects; however, to date a detailed
Externí odkaz:
https://doaj.org/article/cb3b8f2353784562881c61e7a37e7697
Autor:
Giuseppe Verdile, Kevin N. Keane, Vinicius F. Cruzat, Sandra Medic, Miheer Sabale, Joanne Rowles, Nadeeja Wijesekara, Ralph N. Martins, Paul E. Fraser, Philip Newsholme
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Type 2 diabetes (T2DM), Alzheimer’s disease (AD), and insulin resistance are age-related conditions and increased prevalence is of public concern. Recent research has provided evidence that insulin resistance and impaired insulin signalling may be
Externí odkaz:
https://doaj.org/article/de65fd2b05df46b59967626a085fe815
Publikováno v:
Psychol Sch
School districts and other service providers are increasingly aware of the substantial mental health needs of students experiencing family homelessness. Past findings are mixed regarding whether homelessness conveys unique risk beyond the risks assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259325ad2f6de1cd38eee15df01fc3f5
https://doi.org/10.1002/pits.22331
https://doi.org/10.1002/pits.22331