Zobrazeno 1 - 10
of 181
pro vyhledávání: '"A. N. Kapanidis"'
Autor:
Alison Farrar, Conor Feehily, Piers Turner, Alexander Zagajewski, Stelios Chatzimichail, Derrick Crook, Monique Andersson, Sarah Oakley, Lucinda Barrett, Hafez El Sayyed, Philip W. Fowler, Christoffer Nellåker, Achillefs N. Kapanidis, Nicole Stoesser
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Antibiotic resistance is an urgent global health challenge, necessitating rapid diagnostic tools to combat its threat. This study uses citizen science and image feature analysis to profile the cellular features associated with antibiotic res
Externí odkaz:
https://doaj.org/article/08a2250997fc411980c8c2f1abd8345d
Autor:
Alexander Zagajewski, Piers Turner, Conor Feehily, Hafez El Sayyed, Monique Andersson, Lucinda Barrett, Sarah Oakley, Mathew Stracy, Derrick Crook, Christoffer Nellåker, Nicole Stoesser, Achillefs N. Kapanidis
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract The rise of antimicrobial resistance (AMR) is one of the greatest public health challenges, already causing up to 1.2 million deaths annually and rising. Current culture-based turnaround times for bacterial identification in clinical samples
Externí odkaz:
https://doaj.org/article/5ace68d7879e4c06a9f6a6693ebca1a3
Autor:
Christof Hepp, Nicolas Shiaelis, Nicole C. Robb, Alison Vaughan, Philippa C. Matthews, Nicole Stoesser, Derrick Crook, Achillefs N. Kapanidis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The increasing risk from viral outbreaks such as the ongoing COVID-19 pandemic exacerbates the need for rapid, affordable and sensitive methods for virus detection, identification and quantification; however, existing methods for detecting v
Externí odkaz:
https://doaj.org/article/4d11296b02a54aa2b9477fd8652b9037
Publikováno v:
eLife, Vol 10 (2021)
Transcription initiation starts with unwinding of promoter DNA by RNA polymerase (RNAP) to form a catalytically competent RNAP-promoter complex (RPo). Despite extensive study, the mechanism of promoter unwinding has remained unclear, in part due to t
Externí odkaz:
https://doaj.org/article/a30f5b4d3ff2433d975fec7b77a92d47
Autor:
Hannah L Klein, Kenny K.H. Ang, Michelle R. Arkin, Emily C. Beckwitt, Yi-Hsuan Chang, Jun Fan, Youngho Kwon, Michael J. Morten, Sucheta Mukherjee, Oliver J. Pambos, Hafez el Sayyed, Elizabeth S. Thrall, João P. Vieira-da-Rocha, Quan Wang, Shuang Wang, Hsin-Yi Yeh, Julie S. Biteen, Peter Chi, Wolf-Dietrich Heyer, Achillefs N. Kapanidis, Joseph J. Loparo, Terence R. Strick, Patrick Sung, Bennett Van Houten, Hengyao Niu, Eli Rothenberg
Publikováno v:
Microbial Cell, Vol 6, Iss 1, Pp 65-101 (2019)
Genomes are constantly in flux, undergoing changes due to recombination, repair and mutagenesis. In vivo, many of such changes are studies using reporters for specific types of changes, or through cytological studies that detect changes at the single
Externí odkaz:
https://doaj.org/article/284d1fa54b1b42a89ebab92b52616ba5
Publikováno v:
Quarterly Reviews of Biophysics. :1-27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c64f154d8b39fbb7730a9be7688f5282
https://doi.org/10.1017/s0033583523000021
https://doi.org/10.1017/s0033583523000021
Autor:
Eitan Lerner, Anders Barth, Jelle Hendrix, Benjamin Ambrose, Victoria Birkedal, Scott C Blanchard, Richard Börner, Hoi Sung Chung, Thorben Cordes, Timothy D Craggs, Ashok A Deniz, Jiajie Diao, Jingyi Fei, Ruben L Gonzalez, Irina V Gopich, Taekjip Ha, Christian A Hanke, Gilad Haran, Nikos S Hatzakis, Sungchul Hohng, Seok-Cheol Hong, Thorsten Hugel, Antonino Ingargiola, Chirlmin Joo, Achillefs N Kapanidis, Harold D Kim, Ted Laurence, Nam Ki Lee, Tae-Hee Lee, Edward A Lemke, Emmanuel Margeat, Jens Michaelis, Xavier Michalet, Sua Myong, Daniel Nettels, Thomas-Otavio Peulen, Evelyn Ploetz, Yair Razvag, Nicole C Robb, Benjamin Schuler, Hamid Soleimaninejad, Chun Tang, Reza Vafabakhsh, Don C Lamb, Claus AM Seidel, Shimon Weiss
Publikováno v:
eLife, Vol 10 (2021)
Single-molecule FRET (smFRET) has become a mainstream technique for studying biomolecular structural dynamics. The rapid and wide adoption of smFRET experiments by an ever-increasing number of groups has generated significant progress in sample prepa
Externí odkaz:
https://doaj.org/article/acccb8f6f1f1430c8cef78416466d619
Autor:
David Dulin, David L. V. Bauer, Anssi M. Malinen, Jacob J. W. Bakermans, Martin Kaller, Zakia Morichaud, Ivan Petushkov, Martin Depken, Konstantin Brodolin, Andrey Kulbachinskiy, Achillefs N. Kapanidis
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
RNA synthesis by bacterial RNA polymerase is interrupted by pauses but their role in RNA synthesis is poorly understood. Here the authors use single-molecule FRET and biochemical analysis to show that pausing regulates branching between the abortive
Externí odkaz:
https://doaj.org/article/5a7bdeadb61d4f6d961109f5e5564849
Publikováno v:
ChemPhysChem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d20ff882465543d3c9ce65a7aa45b18d
https://doi.org/10.1002/cphc.202300175
https://doi.org/10.1002/cphc.202300175
Autor:
Mathew Stracy, Marcin Jaciuk, Stephan Uphoff, Achillefs N. Kapanidis, Marcin Nowotny, David J. Sherratt, Pawel Zawadzki
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Nucleotide excision repair is able to identify and remove a wide range of DNA helix distorting lesions from the genome. Here the authors use single molecule imaging of UvrA and UvrB molecules and suggest a two-step ‘scan and recruit’ model for Uv
Externí odkaz:
https://doaj.org/article/1fdccc86530b44ceb8758d17f008c0d5