Zobrazeno 1 - 10
of 613
pro vyhledávání: '"A. Mosyak"'
Molecular insights into recognition of GUCY2C by T-cell engaging bispecific antibody anti-GUCY2CxCD3
Autor:
Pragya Rampuria, Lidia Mosyak, Adam R. Root, Kristine Svenson, Michael J. Agostino, Edward R. LaVallie
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The intestinal epithelial receptor Guanylyl Cyclase C (GUCY2C) is a tumor-associated cell surface antigen expressed across gastrointestinal malignancies that can serve as an efficacious target for colorectal cancer immunotherapy. Here, we de
Externí odkaz:
https://doaj.org/article/db669487a90c46ae8d16d8a5021ff01b
Autor:
Park, Jinseo, Zuo, Hao, Frangaj, Aurel, Fu, Ziao, Yen, Laura Y., Zhang, Zhening, Mosyak, Lidia, Slavkovich, Vesna N., Liu, Jonathan, Ray, Kimberly M., Cao, Baohua, Vallese, Francesca, Geng, Yong, Chen, Shaoxia, Grassucci, Robert, Dandey, Venkata P., Tan, Yong Zi, Eng, Edward, Lee, Yeji, Kloss, Brian, Liu, Zheng, Hendrickson, Wayne A., Potter, Clinton S., Carragher, Bridget, Graziano, Joseph, Conigrave, Arthur D., Frank, Joachim, Clarke, Oliver B., Fan, Qing R.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2021 Dec . 118(51), 1-10.
Externí odkaz:
https://www.jstor.org/stable/27117539
Autor:
Fu, Jiao, Hoffman, Alon, Kuntumalla, Mohan Kumar, Wang, Hong-xing, Chen, Daming, Mosyak, Albert, Yossifon, Gilad
Publikováno v:
In Diamond & Related Materials December 2022 130
Autor:
Alette R. Brinth, Kristine Svenson, Lidia Mosyak, Orla Cunningham, Timothy Hickling, Matthew Lambert
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Administration of therapeutic antibodies can elicit adverse immune responses in patients through the generation of anti-drug antibodies that, in turn, reduce the efficacy of the therapeutic. Removal of foreign amino acid content by humanizat
Externí odkaz:
https://doaj.org/article/8c0f30b6ecf14d15bc26d61864eccaa1
Autor:
Rampuria, Pragya1 (AUTHOR) pragya.rampuria@pfizer.com, Mosyak, Lidia1 (AUTHOR) lidia.mosyak@pfizer.com, Root, Adam R.2 (AUTHOR), Svenson, Kristine1 (AUTHOR), Agostino, Michael J.3 (AUTHOR), LaVallie, Edward R.1 (AUTHOR)
Publikováno v:
Scientific Reports. 8/17/2023, Vol. 13 Issue 1, p1-15. 15p.
Autor:
Liu, Weifeng, Maben, Zachary, Wang, Carole, Lindquist, Kevin C., Li, Manqing, Rayannavar, Vinayak, Lopez Armenta, Ilsel, Nager, Andrew, Pascua, Edward, Dominik, Pawel K., Oyen, David, Wang, Hui, Roach, Rachel Carson, Allan, Corey M., Mosyak, Lidia, Chaparro-Riggers, Javier
Publikováno v:
In Journal of Biological Chemistry October 2021 297(4)
Autor:
Ella Fung, Liya Kang, Diana Sapashnik, Susan Benard, Annette Sievers, Yan Liu, Guoying Yan, Jing Zhou, Linette Rodriguez, Weijun Ma, Wayne R. Stochaj, Edward LaVallie, Liliana Wroblewska, Kerry Kelleher, Amy Tam, Olivier Bezy, Danna Breen, Jeffrey R. Chabot, Tao He, Laura Lin, Zhidan Wu, Lidia Mosyak
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract GDF15 is a distant TGF-β family member that induces anorexia and weight loss. Due to its function, GDF15 has attracted attention as a potential therapeutic for the treatment of obesity and its associated metabolic diseases. However, the pha
Externí odkaz:
https://doaj.org/article/8c6c1df6d01f479188c806163a2d9e3d
Akademický článek
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Autor:
Zuo, Hao, Glaaser, Ian, Zhao, Yulin, Kurinov, Igor, Mosyak, Lidia, Wang, Haonan, Liu, Jonathan, Park, Jinseo, Frangaj, Aurel, Sturchler, Emmanuel, Zhou, Ming, McDonald, Patricia, Geng, Yong, Slesinger, Paul A., Fan, Qing R.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2019 Apr . 116(17), 8370-8379.
Externí odkaz:
https://www.jstor.org/stable/26703514
Autor:
Sharon M. Campbell, Joseph DeBartolo, James R. Apgar, Lydia Mosyak, Virginie McManus, Sonia Beyer, Eric M. Bennett, Matthew Lambert, Orla Cunningham
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Despite substantial technological advances in antibody library and display platform development, the number of approved biotherapeutics from displayed libraries remains limited. In vivo, 20–50% of peripheral B cells undergo a process of receptor ed
Externí odkaz:
https://doaj.org/article/1a3148ad6bc644088284dab2ad0a2c77