Soft Set Theory for Decision Making in Computational Biology Under Incomplete Information

Autor: Beatriz Santos-Buitrago, Adrian Riesco, Merrill Knapp, Jose Carlos R. Alcantud, Gustavo Santos-Garcia, Carolyn Talcott

Publikováno v: IEEE Access, Vol 7, Pp 18183-18193 (2019)

The study of biological systems is complex and of great importance. There exist numerous approaches to signal transduction processes, including symbolic modeling of cellular adaptation. The use of formal methods for computational biological systems e

Externí odkaz: https://doaj.org/article/5a439512edd044d9b5624601dbc70887

Contraceptive and Infertility Target DataBase: a contraceptive drug development tool for targeting and analysis of human reproductive specific tissues†

Autor: John Pywtorak, Greg McCain, Diana L. Blithe, Peter B. Madrid, Subarna Sinha, Merrill Knapp, Toufan Parman, Stuart B. Moss, J Mark Gondek, Min S Lee, Jill Long, Colin VanDervoort, Kenneth Wingerden, Stephen E. Gerrard

Publikováno v: Biol Reprod

The long and challenging drug development process begins with discovery biology for the selection of an appropriate target for a specific indication. Target is a broad term that can be applied to a range of biological entities such as proteins, genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67de0e3318708c1afdcb0d128989408a
https://doi.org/10.1093/biolre/ioab172

DatumKB: A Database of Biological Experimental Results

Autor: Merrill Knapp, Tim McCarthy, Carolyn L. Talcott

1.ABSTRACTDatumKB is a freely accessible database of experimental results involving the function and regulation of human proteins in cultured cells. The results are manually curated from biological research literature using a shorthand language and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fc70a9d8538dea6b1a5accaa797ee2f
https://doi.org/10.1101/2021.06.25.449966

Transcriptional Response of SK-N-AS Cells to Methamidophos (Extended Abstract)

Autor: Peter Avar, Lida Parvin, Maria I. Zavodszky, Brian Michael Davis, Merrill Knapp, Mark-Oliver Stehr, Christine A. Morton, Albert-Baskar Arul, Ziad J. Sahab, Akos Vertes, Andrew R. Korte, Christopher J. Sevinsky, Andrew Poggio, Deborah I. Bunin, Denise Nishita, Carolyn L. Talcott

Publikováno v: Computational Methods in Systems Biology ISBN: 9783030313036
CMSB

Transcriptomics response of SK-N-AS cells to methamidophos (an acetylcholine esterase inhibitor) exposure was measured at 10 time points between 0.5 and 48 h. The data was analyzed using a combination of traditional statistical methods, machine learn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dfcdea11eafeb4e97fee13bc4b05d87e
https://doi.org/10.1007/978-3-030-31304-3_29

Epidermal Growth Factor Signaling towards Proliferation: Modeling and Logic Inference Using Forward and Backward Search

Autor: Adrián Riesco, Merrill Knapp, Gustavo Santos-García, Javier De Las Rivas, Carolyn L. Talcott, Beatriz Santos-Buitrago

Publikováno v: BioMed Research International, Vol 2017 (2017)
BioMed Research International
GREDOS. Repositorio Institucional de la Universidad de Salamanca
instname
Digital.CSIC. Repositorio Institucional del CSIC

In biological systems, pathways define complex interaction networks where multiple molecular elements are involved in a series of controlled reactions producing responses to specific biomolecular signals. These biosystems are dynamic and there is a n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09765bbb1a1169ecdba790c0ecb61ae
https://doaj.org/article/b16efb14015846c2b7e65c18f914f0b5