Zobrazeno 1 - 10
of 107
pro vyhledávání: '"A. Maxwell Burroughs"'
Autor:
Pratik Rajendra Patil, A. Maxwell Burroughs, Mohit Misra, Federico Cerullo, Carlos Costas Insua, Hao-Chih Hung, Ivan Dikic, L. Aravind, Claudio A.P. Joazeiro
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113100- (2023)
Summary: In ribosome-associated quality control (RQC), nascent polypeptides produced by interrupted translation are modified with C-terminal polyalanine tails (“Ala-tails”) that function outside ribosomes to induce ubiquitylation by E3 ligases Pi
Externí odkaz:
https://doaj.org/article/9f8d3f9ceb3e41d9920d13ffab44615f
Publikováno v:
Viruses, Vol 14, Iss 9, p 1977 (2022)
NAD+ and ADP-ribose (ADPr)-containing molecules are at the interface of virus–host conflicts across life encompassing RNA processing, restriction, lysogeny/dormancy and functional hijacking. We objectively defined the central components of the NAD+
Externí odkaz:
https://doaj.org/article/88c3f7e83c424f6c8aa83d93f521896c
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The origin of eukaryotes was marked by the emergence of several novel subcellular systems. One such is the calcium (Ca2+)-stores system of the endoplasmic reticulum, which profoundly influences diverse aspects of cellular function including signal tr
Externí odkaz:
https://doaj.org/article/8740205a119049539d304753d89460d9
Publikováno v:
iScience, Vol 9, Iss , Pp 192-208 (2018)
Summary: The provenance of several components of major uniquely eukaryotic molecular machines are increasingly being traced back to prokaryotic biological conflict systems. Here, we demonstrate that the N-terminal single-stranded DNA-binding domain f
Externí odkaz:
https://doaj.org/article/75e971a5937c4a4ca332a6cda8e74af6
Autor:
Robert S. Brzozowski, Mirella Huber, A. Maxwell Burroughs, Gianni Graham, Merryck Walker, Sameeksha S. Alva, L. Aravind, Prahathees J. Eswara
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Bacteria adapt to different environments by regulating cell division and several conditions that modulate cell division have been documented. Understanding how bacteria transduce environmental signals to control cell division is critical in understan
Externí odkaz:
https://doaj.org/article/2314ed69e60e4426801e98349f571187
Autor:
Lakshminarayan M. Iyer, Vivek Anantharaman, Arunkumar Krishnan, A. Maxwell Burroughs, L. Aravind
Publikováno v:
Viruses, Vol 13, Iss 1, p 63 (2021)
Jumbo phages have attracted much attention by virtue of their extraordinary genome size and unusual aspects of biology. By performing a comparative genomics analysis of 224 jumbo phages, we suggest an objective inclusion criterion based on genome siz
Externí odkaz:
https://doaj.org/article/4334188b47ed4d62bde09055c30c3722
Publikováno v:
eLife, Vol 10 (2021)
Several homologous domains are shared by eukaryotic immunity and programmed cell-death systems and poorly understood bacterial proteins. Recent studies show these to be components of a network of highly regulated systems connecting apoptotic processe
Externí odkaz:
https://doaj.org/article/c54f39a734f74d12b4fc619c2cc36e8f
Publikováno v:
eLife, Vol 9 (2020)
Social cellular aggregation or multicellular organization pose increased risk of transmission of infections through the system upon infection of a single cell. The generality of the evolutionary responses to this outside of Metazoa remains unclear. W
Externí odkaz:
https://doaj.org/article/a0f90e4cb6064018b52010f1844631b0
Publikováno v:
Annual Review of Biomedical Data Science. 5:367-391
Biological replicators, from genes within a genome to whole organisms, are locked in conflicts. Comparative genomics has revealed a staggering diversity of molecular armaments and mechanisms regulating their deployment, collectively termed biological
Publikováno v:
Viruses. 14(9)
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